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| 1 | Ansa pancreatica as a predisposing factor for recurrent acute pancreatitis显示文摘AIM To determine the non-biased prevalence and clinical significance of ansa pancreatica in patients with acute pancreatitis using magnetic resonance imaging(MRI).METHODS Our institutional review board approved this crosssectional study, which consisted of a community-based cohort of 587 consecutive participants in a whole-body health-check program, and 73 subjects with episode of acute pancreatitis(55 patients with a single episode of acute pancreatitis, and 18 patients with recurrent acute pancreatitis). All of the subjects underwent abdominal MRI including magnetic resonance cholangiopancreatography, medical examinations, and blood tests. Two board-certified, diagnostic, abdominal radiologists evaluated the images, and ansa pancreatica was diagnosed based on its characteristic anatomy on MRI.RESULTS Compared with the community group [5/587(0.85%)], patients with recurrent acute pancreatitis had a significantly higher frequency of ansa pancreatica [2/18(11.1%)](P = 0.016; OR = 14.3; 95%CI: 1.27-96.1), but not compared with patients with single-episode acute pancreatitis [1/55(1.8%)](P = 0.42; OR = 2.1; 95%CI: 0.44-19.7). Multiple logistic regression analysis using age, alcohol intake, presence of ansa pancreatica, and presence of autoimmune disease as independent covariates, revealed a significant relationship between the presence of ansa pancreatica and recurrent acute pancreatitis. The presence of autoimmune disease was also significantly associated with the onset of recurrent acute pancreatitis. On the other hand, neither age nor alcohol intake were significantly related to the onset of recurrent acute pancreatitis.CONCLUSION The present study is the first to provide robust evidence that the presence of ansa pancreatica is significantly associated with recurrent acute pancreatitis. | Takana Yamakawa Hayashi Wataru Gonoi Takeharu Yoshikawa Naoto Hayashi Kuni Ohtomo | 2016 | World Journal of Gastroenterology2016，22，40： | 2 |
| 2 | Regulation of Ca^2+ channel expression at the cell surface by the small G-protein kir/Gem显示文摘 | BEGUIN P NAGASHIMA K GONOI T | 2001 | Nature2001，411，： | 1 |
| 3 | Reconstitution of IKATP: an inward rectifier subunit plus the sulfonylurea receptor 显示文摘 | Inagaki N Gonoi T Clement J P 4th | 1995 | Science1995，270，： | 1 |
| 4 | A family of sulfonylurea receptors determines the pharmacological properties of ATP-insensitive K+ channels显示文摘 | Inagaki N Gonoi T Clement J P | 1996 | Neuron1996，16，5： | 1 |
| 5 | Reconstitution of IKATP:An inward rectifier subunit plus the sulfonylurea receptor显示文摘 | Inagaki N Gonoi T Clement J P | 1995 | Science1995，270，5239： | 1 |
| 6 | Effects of fluoroquinolones on insulin secretion and β-cell ATP-sensitive K + channels显示文摘 | Atsunori Saraya Masaaki Yokokura Tohru Gonoi Susumu Seino | 2004 | European Journal of Pharmacology2004，，1： | 1 |
| 7 | The effects of mitiglinide (KAD - 1229) ,a new anti - diabetic drug,on ATP- sensitive K channels and insulin secretion: comparison with the sulfonylureas and nateglinide 显示文摘 | Sunaga Y Gonoi T Shibasaki T | 2001 | Eur J Pharmacol2001，431，1： | 1 |
| 8 | Reconstitutlon of IK ATP: An in- wardrectifier subunit plus the sulfonylurea receptor 显示文摘 | Inagaki N Gonoi T Clement JP | 1995 | Science1995，270，5239： | 1 |
| 9 | The effects of mitiglinide (KAD 1229), a new anti- diabetic drug, on ATP- sensitive K + channels and insulin secretion: comparison with the sulfonylureas and neteglinide显示文摘 | Sunga Y Gonoi T Shibasaki T | 2001 | Eur J Pharmaeol2001，431，1： | 1 |
| 10 | A family of sulfonylurea receptors determines the pharmacological properties of ATPsensitive K^+ channels显示文摘 | Inagaki N Gonoi T Clement IV | 1996 | Neuron1996，16，： | 1 |
| 11 | A family of sulfonylurea receptors determines the pharmacological properties of ATPsensitive K+ channels显示文摘 | Gonoi T Clement JP | 1996 | Neuron1996，16，： | 1 |
| 12 | The effects of mitiglinide (KAD-1229), a new anti diabetic drug, on ATP sensitive K^+ channels and insulin secretion: compari son with the sulfonylureas and nateglinide显示文摘 | Yasuhiro Sunaga Tohru Gonoi Tadao Shibasaki | 2001 | European Journalof Pharmacology2001，431，： | 1 |
| 13 | Reconstitution of IKATP:an inward rectifier subunit plus the sulfonylures receptor显示文摘 | Inagaki N Gonoi T Clement JP | 1995 | Science1995，270，： | 1 |
| 14 | Effect of fluoro- qninolones on insulin and beta-cell ATP-sensitive K^+ channels 显示文摘 | Saraya A Yokokura M Gonoi T | 2004 | Eur J Pharmacol2004，497，1： | 1 |
| 15 | Voxel based analysis of the diffusiontensor显示文摘 | Abe O Takao H Gonoi W | 2010 | Neuroradiology2010，52，8： | 1 |
| 16 | Effects of fluoroquinolones on insulin secretion and beta-cell ATP-sensitive K+ channels显示文摘 | Yokokura M Gonoi T | 2004 | European Journal of Pharmacology2004，497，1： | 1 |
| 17 | Effects of fluoroquinolones on insulin secretion and beta-cell ATP-sensitive K+ channels显示文摘 | Saraya A Yokokura M Gonoi T | 2004 | Eur J Pharmacol2004，497，： | 1 |
| 18 | Neural network approach to the ECM problem显示文摘 | Keniti Gonoi Takakazu Kurokawa | 2001 | Systems and Computers in Japan2001，32，1： | 1 |
| 19 | The effects of mitiglinide ( KAD-1229 ) , a new anti-diabetic drug, on ATP-sensitive K + channels and insulin secretion:comparison with the sulfonylureas and nateglinide 显示文摘 | Sunaga Y Gonoi T Shibasak T | 2001 | Eur J Pharmacol2001，431，1： | 1 |
| 20 | Effects of fluoroquinolones on insulin secretion and beta-cell ATP-sensitive K+ channels显示文摘 | Yokokura M Gonoi T Sdno S | 2004 | Eur J Pharmacol2004，497，： | 1 |
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