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| 1 | Circadian rhythms in the pathogenesis of gastrointestinal diseases显示文摘The etiology of digestive pathologies such as irritable bowel syndrome(IBS), inflammatory bowel diseases(IBD) and cancer is not yet fully understood. In recent years, several studies have evidenced circadian variations in mechanisms involved in digestive health. In situations of disturbed circadian rhythms(chronodisruption) where the central clock and the peripheral clocks receive incoherent signals, the synchronicity is lost producing implications for health. This lack of coordination could alter the tissue function and cause long term damage to the organs. Life habits such as sleep, physical exercise, social interaction, and feeding times are determinants for stability and integrity of circadian rhythms. In recent years, experimental and clinical studies have consistently evidenced that the alteration of circadian rhythms is associated with the development of digestive pathologies mainly linked to dismotility or changes in microbiota composition. Likewise, it seems reasonable to deep into the importance of chronodisruption as a factor that may participate in the development of pathologies such as IBS, IBD and digestive cancers. Moreover, life habits respecting circadian rhythms should be promoted for the prevention of these diseases. Further studies will allow us a better understanding of the mechanisms acting at molecular level, and the development of new therapeutic targets. | Pilar Codonr-Franch Marie Gombert | 2018 | World Journal of Gastroenterology2018，24，38： | 7 |
| 2 | Sampling Variability of Liver Biopsy in Nonalcoholic Fatty Liver Disease显示文摘 | Vlad Ratziu Frédéric Charlotte Agnès Heurtier Sophie Gombert Philippe Giral Eric Bruckert André Grimaldi Frédérique Capron Thierry Poynard | 2005 | Gastroenterology2005，，7： | 4 |
| 3 | Antireflective transparent covers for solar devices 显示文摘 | Gombert A Glaubitt W Rose K | 2000 | Solar Energy2000，68，4： | 2 |
| 4 | Recombinant gene expres-sion in Escherichia coli cultivation using lactose as in-ducer显示文摘 | Gombert A K Kilikian B V | 1998 | Journal of Biotechnology1998，60，12： | 1 |
| 5 | The use of autoecological and environmental parameters for establishing the status of lichen vegetation in a baseline study for a long term monitoring survey显示文摘 | Gombert S Asta J Seaward M R D | 2005 | Environmental Pollution2005，135，： | 1 |
| 6 | CC chemokine ligand 18,an atopic dermatitis-associated and dendritic cell-derived chemokine,is regulated by staphylococcal products and allergen exposure显示文摘 | Gombert M eu-Nosjean MC | 2004 | J Immunol2004，173，： | 1 |
| 7 | Efficiency limiting factors of organic bulk heterojunction solar cells identified by electrical impedance spectroscopy显示文摘 | M. Glatthaar M. Riede N. Keegan K. Sylvester-Hvid B. Zimmermann M. Niggemann A. Hinsch A. Gombert | 2006 | Solar Energy Materials and Solar Cells2006，，5： | 1 |
| 8 | The relationship be- tween intravenous fluid contamination and the frequency of tubing replacement显示文摘 | Josephson A Gombert ME Sierra MF | 1985 | Infect Control1985，6，9： | 1 |
| 9 | A functionalgenomics approach using metabolomics and in silico pathwayanalysis 显示文摘 | FORSTER J GOMBERT A K NIELSEN J | 2002 | Biotechnol Bioeng2002，79，7： | 1 |
| 10 | Early quantitativeand functional deficiency of NKl-like thymocytes in the NOD mouse显示文摘 | Herbelin A Tancrede-Bohin E | 1996 | J Immunol1996，26，： | 1 |
| 11 | Net-work identification and flux quantification in the central metabolism of Saccharomyces cerevisiae under different conditions of glucose repres-sion显示文摘 | GOMBERT A K Dos SANTOS M M CHRISTENSEN B | 2001 | Journal of Bacteriology2001，183，4： | 1 |
| 12 | Impact of catalytic ozonation on the removal of a chelating agent and surfactants in aqueous solution显示文摘 | Karpel Vel Leitner N Gombert B Legube B | 1998 | Water Sci Technol1998，38，45： | 1 |
| 13 | Efficacy of thalidomide in the treatment of refractory ankylosing spondylitis显示文摘 | Breban M Gombert B Amor B | 1999 | Arthritis Rheum1999，42，： | 1 |
| 14 | A global optimization approach for metabolic flux analysis based on labeling balances显示文摘 | RIASCOS C A M GOMBERT A K PINTO J M | 2005 | Computers&Chemical Engineering2005，29，3： | 1 |
| 15 | Sampling Variability of Liver Biopsy in Nonalcoholic Fatty Liver Disease显示文摘 | Vlad Ratziu Frédéric Charlotte Agnès Heurtier Sophie Gombert Philippe Giral Eric Bruckert André Grimaldi Frédérique Capron Thierry Poynard | 2005 | Gastroenterology2005，，7： | 1 |
| 16 | 显示文摘 | Gombert JM Herbilin A Tancrede BE | 1996 | Eur J Immunol1996，26，12： | 1 |
| 17 | Analysis of flux estimates based on 13C - labelling experiments显示文摘 | Christensen B Karoly Gombert A Nielsen J | 2002 | European Journal of Biochemistry2002，269，11： | 1 |
| 18 | Phonological awareness as a predictorof recoding skills and syntactic awareness as a predictor ofcomprehension skills 显示文摘 | Demont E Gombert J E | 1996 | British Journal of EducationalPsychology1996，66，： | 1 |
| 19 | Recombinant gene expression in Escherichia coli cultivation using lactose as inducer显示文摘 | Gombert A K Kilikian B V | 1998 | J Biotech1998，60，12： | 1 |
| 20 | Role of karstic dissolution in global carbon cycle显示文摘 | Gombert P | 2002 | Global and Planetary Change2002，33，12： | 1 |
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