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| 1 | 渗透压对血管内皮细胞中NO合成酶活性的影响及其机制研究显示文摘目的 :研究非等渗压浓度对血管内皮细胞NO合成酶活性的影响 ,并探索其发生机制。方法 :使血管内皮细胞暴露于低渗 (2 0 5mOsm)或高渗透压 (4 10mOsm)培养液 ,用Griess法测定NO合成酶 (NOS)活性 ,以Northernblot ting观测细胞iNOS和eNOS基因表达的变化。 结果 :非等渗压浓度可使血管内皮细胞中NOS活性显著升高。细胞NOS活性变化具有明显的时间效应规律 ,低渗透压浓度效应产生的效应早于高渗透压浓度 ,且低渗透压浓度的影响较高渗透压浓度更为明显。Dexamethasone对这种非等渗透压诱导的NOS活性没有明显作用 ,给予cyclohex imide,不影响非等渗压诱导的这种差异。Nothernblot分析表明 :非等渗压浓度不诱导iNOS基因表达 ,而使eNOSmRNA表达增加。结论 :非等渗透压浓度诱导血管内皮细胞NOS活性升高 ,eNOS基因表达增强是其主要机制之一。 | 钱令嘉 Axel Goedecke Jungen Schrader | 2001 | 中国应用生理学杂志2001，17，2： | 3 |
| 2 | Tumor necrosis factor- acontributes to ischemia - and reperfusion - induced endothelial activation in isolated hearts显示文摘 | Kupatt C Hahazettl H Goedecke A | 1999 | Circ Res1999，84，4： | 1 |
| 3 | Tumor necrosis factor-alpha contributes to ischemia-and reperfusion-induced endothelial aetivation in isolated hearts 显示文摘 | Kupatt C Habazettl H Goedecke A | 1999 | Circ Res1999，84，4： | 1 |
| 4 | Treatment of refractory acute GVHD with third-party MSC expanded in platetet lysate-containing medium显示文摘 | von Bonin M Stolzel F Goedecke A | 2009 | Bone Marrow Transplant2009，43，3： | 1 |
| 5 | Scattering by irregular inhomogeneous particles via the digitized Green's function algorithm显示文摘 | Goedecke G H O'Brien S G | 1988 | Applied Optics1988，27，12： | 1 |
| 6 | Ultasonc Or MFL Inspection:Which Technology is Better for You?显示文摘 | Hartmut Goedecke | 2003 | Pipeline & Gas Journal2003，230，10： | 1 |
| 7 | New insights in- to myosin evolution and elassification显示文摘 | FOTH B J GOEDECKE M C SOLDATI D | 2006 | Proc Natl Acad Sci USA2006，103，10： | 1 |
| 8 | Prediction of energy expenditure from heart rate monitoring during sub- maximal exercise 显示文摘 | Keytel L R Goedecke J H Noakes T D | 2005 | J Sports Sci2005，23，3： | 1 |
| 9 | Early identification of bacterial leading to central venous catheter contamination显示文摘 | Jeske C Raedler C Goedecke AV | 2003 | Society of Cardiovascu Anes2003，97，4： | 1 |
| 10 | The development of an early extubati on algorithm for patients after cardiac surgery显示文摘 | Goedecke RS | 1996 | Heart & Lung1996，25，1： | 1 |
| 11 | Pharmacological characterization of the chemokine receptor, CCR5显示文摘 | Mueller A Mahmoud N G Goedecke M C Mckeating J A Strange P G | 2002 | Br J Pharmacol2002，135，： | 1 |
| 12 | Ultrasonie Or MFL Inspection: Which Technology is Better for You? 显示文摘 | Hartmut Goedecke | 2003 | Pipeline & Gas Journal2003，10，： | 1 |
| 13 | Early identification of bacterial leading to central venous catheter contamination 显示文摘 | Jeske C Raedler C Von Goedecke A | 2003 | Anesth Analg2003，97，4： | 1 |
| 14 | Influence of ventilation strate-gies on survival in severe controlled hemorrhagic shock 显示文摘 | Herff H Paal P von Goedecke A | 2008 | Crit CareMed2008，36，9： | 1 |
| 15 | Ultrasonic corrosion survey-what you get and what you don't get显示文摘 | GOEDECKE H | 1996 | Pipes & Pipelines International1996，41，1： | 1 |
| 16 | Mechanoinduction of lymph vessel expansion显示文摘 | Planas-Paz L Strilic B Goedecke A | 2012 | EMBO J2012，31，4： | 1 |
| 17 | Corrosion surveys with the ultraScan pig显示文摘 | GOEDECKE H | 1990 | Corrosion Prevention & Control1990，37，2： | 1 |
| 18 | Differential effect of platelet-rich plasma and fetal calf serum on bone marrow-derived human mesenchymal stromal cells expanded in vitro显示文摘 | Goedecke A Wobus M Krech M | | 0，，08： | 1 |
| 19 | Metabolic setpoint control mechanisms in different physiological systems at rest and during exercise显示文摘 | ST CLAIR GIBSON A GOEDECKE J H HARLEY Y X | 2005 | J Theor Biol2005，7236，1： | 1 |
| 20 | Prediction of energy expenditure from heart rate monitoring during submaximal exercise显示文摘 | Keytel LR Goedecke JH Noakes TD | 2005 | J Sports Sci2005，23，3： | 1 |
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