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| 1 | The roles of MAPKs in disease显示文摘印射响应许多 ligands 和房间刺激涉及大量的细胞的小径和功能的家族 ases transduce 信号。MAPK 的异常或不恰当的功能现在在从癌症到煽动性的疾病到肥胖和糖尿病的疾病被识别了。在许多房间类型, MAPK ERK1/2 被连接到细胞增殖。因为在地岬和 B-Raf 的变化,能激活 ERK1/2 串联,在许多人的肿瘤被发现, ERK1/2 被认为在一些癌症起一个作用。发信号的反常 ERK1/2 也在 polycystic 肾疾病被发现了,并且象 cardio-facio-cutaneous 症候群那样的严肃的发展混乱在 ERK1/2 串联的部件从变化产生。ERK1/2 在区分得好的房间是必要的并且在神经原并且在上皮的极性的维护被连接了到长期的 potentiation。另外, ERK1/2 为在胰腺的贝它房间的胰岛素基因抄写是重要的,它响应传播葡萄糖的增加生产胰岛素在有机体允许有效葡萄糖利用和存储。导致或镇压的营养素和荷尔蒙胰岛素分泌物以在贝它房间上反映能分泌的需求的一种方式激活或禁止 ERK1/2。在这和另外的规章的小径的骚乱可以导致对某些人的混乱的病原学的 ERK1/2 的贡献。 | Michael C Lawrence Arif Jivan Chunli Shao Lingling Duan Daryl Goad Elma Zaganjor Jihan Osborne Kathleen McGlynn Steve Stippec Svetlana Earnest Wei Chen Melanie H Cobb | 2008 | Cell Research2008，18，4： | 64 |
| 2 | On optimal filtering of GPS dual-frequency observations without using orbit information显示文摘 | Euler H Goad C C | 1991 | Bulletin Geodesique1991，65，： | 1 |
| 3 | A New Approach to Precision Airborne GPS Positioning for Photogrammetry 显示文摘 | Goad C Yang M | 1997 | Photogrammetric Engineering & Remote Sensing1997，63，9： | 1 |
| 4 | Early intensive care unit mobility therapy in the treatment of acu~ce respiratory failure显示文摘 | Morris P E Goad A Thompson C | 2008 | Crit Care Med2008，36，8： | 1 |
| 5 | Ruminal microbial and fermentative changes associated with experimentally induced subaeute acidosis in steers显示文摘 | Goad D W Goad C L | 1998 | Journal of Animal Science1998，76，1： | 1 |
| 6 | Fractionation Trends of the Nb- and Ta-bearing Oxide Minerals in the Greer Lake Pegmatitic Granite and Its Pegmatite Aureole,Southeastern Manitoba显示文摘 | CERNY P GOAD B E HAWTHORNE F C | 1986 | Amer- ican Mineralogist1986，71，34： | 1 |
| 7 | Kernel color variability of hard white and hard red winter wheat显示文摘 | WU J CARVER B F GOAD C L | 1999 | Crop Sci1999，30，： | 1 |
| 8 | Early intensive care unit mobility therapy in the treatment of acute respiratory failure 显示文摘 | Morris PE Goad A Thompson C | 2008 | Crit Care Med2008，36，8： | 1 |
| 9 | Gravimetric Tidal Loading Computed from Integrated Green's function显示文摘 | Goad C C | 1980 | J Geophys Res1980，，： | 1 |
| 10 | Early intensive care unit mobility therapy in the treatment of acute respiratory failure 显示文摘 | Morris PE Goad A Thompson C | 2008 | Crit Care Med2008，36，8： | 1 |
| 11 | Use of dietary cation anion difference for control of urolithiasis risk factors in goats显示文摘 | Jones M L Streeter R N Goad C L | 2009 | American Journal of Veterinary Research2009，70，1： | 1 |
| 12 | Use of dietary cation anion dif- ference for control of urolithiasis risk factors in goats显示文摘 | Jones M L Streeter R N Goad C L | 2009 | American Journal of Veterinary Research2009，70，1： | 1 |
| 13 | Fractionation trends of the Nb- and Ta-bearing oxid minerals in the Greer Lake pegmatitic granite and its pegmatitic aureole, southeastern Manitoba 显示文摘 | Cerny P Goad B E Hawthorne F C | 1986 | Am Miner1986，71，： | 1 |
| 14 | Early intensive care unit mob- ility therapy in the treatment of acute respiratory failure显示文摘 | Morris PE Goad A Thompson C | 2008 | Crit Care Med2008，36，8： | 1 |
| 15 | Linking teratogen- esis, growth, and DNA photodamage to artificial ultra- violet b radiation in Xenopus laevis larvae 显示文摘 | Bruggeman D J Bantle J A Goad C | 1998 | Environ- mental Toxicology and Chemistry1998，17，10： | 1 |
| 16 | Optimal Filtering of Pseucloranges and Phases from Single frequency GPS Receivers 显示文摘 | GOAD C C | 1990 | Navigation1990，37，3： | 1 |
| 17 | The effectsof dietary butylated hydroxytoluene on liver and colon tumor development in mice显示文摘 | LINDENSCHMIDT R C TRYKA A F GOAD M E | 1986 | Toxicology1986，2，38： | 1 |
| 18 | On optimal filtering of GPS dual fre- quency observations without using orbit information显示文摘 | Euler H Goad C | 1991 | Bulletin Geodesique1991，65，： | 1 |
| 19 | The effects of dietary butylated hydroxytoluene on liver and colon tumor development in mice显示文摘 | LINDENSCHMIDT R C TRYKA A F GOAD M E | 1986 | Toxicology1986，38，2： | 1 |
| 20 | On Optimal Filtering of GPS Dual Frequency Observations Without Using Orbit Information显示文摘 | Euler H Goad C | 1991 | Bull Geod1991，65，： | 1 |
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