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| 1 | The roles of MAPKs in disease显示文摘印射响应许多 ligands 和房间刺激涉及大量的细胞的小径和功能的家族 ases transduce 信号。MAPK 的异常或不恰当的功能现在在从癌症到煽动性的疾病到肥胖和糖尿病的疾病被识别了。在许多房间类型, MAPK ERK1/2 被连接到细胞增殖。因为在地岬和 B-Raf 的变化,能激活 ERK1/2 串联,在许多人的肿瘤被发现, ERK1/2 被认为在一些癌症起一个作用。发信号的反常 ERK1/2 也在 polycystic 肾疾病被发现了,并且象 cardio-facio-cutaneous 症候群那样的严肃的发展混乱在 ERK1/2 串联的部件从变化产生。ERK1/2 在区分得好的房间是必要的并且在神经原并且在上皮的极性的维护被连接了到长期的 potentiation。另外, ERK1/2 为在胰腺的贝它房间的胰岛素基因抄写是重要的,它响应传播葡萄糖的增加生产胰岛素在有机体允许有效葡萄糖利用和存储。导致或镇压的营养素和荷尔蒙胰岛素分泌物以在贝它房间上反映能分泌的需求的一种方式激活或禁止 ERK1/2。在这和另外的规章的小径的骚乱可以导致对某些人的混乱的病原学的 ERK1/2 的贡献。 | Michael C Lawrence Arif Jivan Chunli Shao Lingling Duan Daryl Goad Elma Zaganjor Jihan Osborne Kathleen McGlynn Steve Stippec Svetlana Earnest Wei Chen Melanie H Cobb | 2008 | Cell Research2008，18，4： | 64 |
| 2 | Coagulation disorders in cancer显示文摘 | Goad KE Gralnick HR | 1996 | Hematol Oncol Clin North Am1996，10，： | 1 |
| 3 | Control of in- tracellular calcium signaling as a neuroprotective strategy显示文摘 | DUNCAN RS GOAD DL GRILLO MA | 2010 | Molecules2010，15，3： | 1 |
| 4 | Resorbable calcium phosphatebone substitute显示文摘 | Knaack D Goad EB Aiolova M | 1998 | Biomed Mater Res1998，43，： | 1 |
| 5 | On optimal filtering of GPS dual-frequency observations without using orbit information显示文摘 | Euler H Goad C C | 1991 | Bulletin Geodesique1991，65，： | 1 |
| 6 | Potent and spe-cific antitumor efficacy of CMC544,a CD22-targeted immu-noconjugate of calicheamicin,against systemically disseminated B cell lymphoma显示文摘 | DiJoseph J F Goad M E Dougher M M | 2004 | Clin Cancer Res2004，10，24： | 1 |
| 7 | A New Approach to Precision Airborne GPS Positioning for Photogrammetry 显示文摘 | Goad C Yang M | 1997 | Photogrammetric Engineering & Remote Sensing1997，63，9： | 1 |
| 8 | Early intensive care unit mobility therapy in the treatment of acu~ce respiratory failure显示文摘 | Morris P E Goad A Thompson C | 2008 | Crit Care Med2008，36，8： | 1 |
| 9 | Potent and specific antitumor efficacy of CMC-544,a CD22-targeted immunoconjugate of calicheamicin,against systemically disseminated B-cell lymphoma显示文摘 | DiJoseph J F Goad M E Dougher M M | 2004 | Clin Cancer Res2004，10，24： | 1 |
| 10 | Ruminal microbial and fermentative changes associated with experimentally induced subaeute acidosis in steers显示文摘 | Goad D W Goad C L | 1998 | Journal of Animal Science1998，76，1： | 1 |
| 11 | The 220 MHz NMR spectra of phytosterols显示文摘 | RUBINSTEIN I GOAD J L CLAGUE A D H | 1976 | Phytochemistry1976，15，1： | 1 |
| 12 | Rheological Characterization of Melt Compounded Polypropylene/clay Nanocomposites 显示文摘 | Mahmoud Abdel Goad | 2011 | Composites: Part B2011，42，5： | 1 |
| 13 | Fractionation Trends of the Nb- and Ta-bearing Oxide Minerals in the Greer Lake Pegmatitic Granite and Its Pegmatite Aureole,Southeastern Manitoba显示文摘 | CERNY P GOAD B E HAWTHORNE F C | 1986 | Amer- ican Mineralogist1986，71，34： | 1 |
| 14 | Potent and specific antitumor efficacy of CMC-544, a CD22-targeted immunoconjugate of calicheamicin, against systemically disseminated B cell lymphoma 显示文摘 | Dijoseph J F Goad M E Dougher M M | 2004 | Clin Cancer Res2004，10，24： | 1 |
| 15 | Coagulation disorders in cancer显示文摘 | Goad KE Gralnick HR | 1996 | Hematol Oncol Clin North Am1996，10，27： | 1 |
| 16 | Phytosterol sidechain biosynthesis 显示文摘 | Goad LJ Lenton JR Knapp FF 1974 | 1974 | Lipids1974，9，： | 1 |
| 17 | Kernel color variability of hard white and hard red winter wheat显示文摘 | WU J CARVER B F GOAD C L | 1999 | Crop Sci1999，30，： | 1 |
| 18 | Early intensive care unit mobility therapy in the treatment of acute respiratory failure 显示文摘 | Morris PE Goad A Thompson C | 2008 | Crit Care Med2008，36，8： | 1 |
| 19 | Resorbable apatitic bone substitute material, alpha-BSMTM is associated with rapid bone regrowth in defects of rabbit tibias 显示文摘 | Aiolova M Tofighi A | 1997 | J Bone Mineral Res1997，12，1： | 1 |
| 20 | The 220 MHz NMR spectra of phytosterols显示文摘 | Goad LJ Clague ADH | 1976 | Phytocheraistry1976，15，2： | 1 |
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