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您的检索式：作者名="Giuseppe Musardo"
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| 1 | MGUS:Proposal for outpatient management显示文摘The term monoclonal gammopathy of undetermined significance(MGUS) indicates the presence of a monoclonal protein(M-protein) without features of multiple myeloma, Waldenstrom's macroglobulinemia, primary amyloidosis or malignant lymphoproliferative disorders(LPD). While several guidelines on the treatment of LPD exist, many doubts and perplexities still exist on who should treat a MGUS, when and how. Even where MGUS does not require any therapy, the risk of progression to a LPD is 1% per year. This risk does not diminish over time and persists even in patients(pts) whose condition has remained stable for decades, and a prolonged follow up is, therefore, recommended. We met primary care doctors to share and agree on criteria for the management of outpatients with MGUS. Our aim is to draw up guidelines or, at least, suggestions that may help to determine which MGUS pts could be cared for by the primary care doctor and which should be followed by the hematologist. We suggest that once a MGUS is diagnosed, the primary care physician will attend patients with M-protein < 15 g/L if Ig G and pts with M-protein< 10 g/L if Ig A or Ig M, without end-organ damage and without signs and symptoms of LPD. However, a hematological evaluation is recommended for patients with M-protein Ig G > 15 g/L, or M-protein Ig A > 10 g/L, or Ig M > 10 g/L, or any M-protein with end-organ damage(not attributable to any others causes) or with signs and symptoms of LPD, or rapidly increasing M-protein(> 5 g/L per year). | Paolo Savini Giorgio Marano Arianna Lanzi Barbara Castagnari Giuseppe Musardo Annalia Molinari Claudia Cellini Giuseppe Francesco Stefanini | 2012 | World Journal of Hematology2012，1，2： | 0 |
| 2 | Paraparesis induced by extramedullary haematopoiesis显示文摘We describe a case of worsening paraparesis induced by spinal cord compression at T6-T7 levels associated with compensatory extramedullary haematopoiesis from a compound heterozygote for haemoglobin E and for β-thalassemia.An emergency T3-T9 laminectomy was performed with excision of the masses and complete rehabilitation of the patient. | Paolo Savini Arianna Lanzi Giorgio Marano Chiara Carli Moretti Giovanni Poletti Giuseppe Musardo Francesco Giuseppe Foschi Giuseppe Francesco Stefanini | 2011 | World Journal of Radiology2011，3，3： | 0 |
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