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您的检索式：作者名="Gilbert Wunderlich"
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| 1 | Neural consequences of acting in near versus far space: a physiological basis for clinical dissociations 显示文摘 | Weiss PH Marshall JC Gilbert Wunderlich | 2000 | Brain2000，123，12： | 1 |
| 2 | AAV-based gene therapy approaches for genetic forms of tauopathies and related neurogenetic disorders显示文摘Tauopathies comprise a spectrum of genetic and sporadic neurodegenerative diseases mainly characterized by the presence of hyperphosphorylated TAU protein aggregations in neurons or glia.Gene therapy,in particular adeno-associated virus(AAV)-based,is an effective medical approach for difficult-to-treat genetic diseases for which there are no convincing traditional therapies,such as tauopathies.Employing AAV-based gene therapy to treat,in particular,genetic tauopathies has many potential therapeutic benefits,but also drawbacks which need to be addressed in order to successfully and efficiently adapt this still unconventional therapy for the various types of tauopathies.In this Viewpoint,we briefly introduce some potentially treatable tauopathies,classify them according to their etiology,and discuss the potential advantages and possible problems of AAV-based gene therapy.Finally,we outline a future vision for the application of this promising therapeutic approach for genetic and sporadic tauopathies. | MOHAMED AGHYAD AL KABBANI GILBERT WUNDERLICH CHRISTOPH KÖHLER HANS ZEMPEL | 2022 | BIOCELL2022，46，4： | 0 |
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