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1篇 您的检索式:作者名="Germana Grassi"
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1Hepatitis C virus relies on lipoproteins for its life cycle显示文摘Hepatitis C virus(HCV) infects over 150 million people worldwide. In most cases, HCV infection becomes chronic causing liver disease ranging from fibrosis to cirrhosis and hepatocellular carcinoma. Viral persistence and pathogenesis are due to the ability of HCV to deregulate specific host processes, mainly lipid metabolism and innate immunity. In particular, HCV exploits the lipoprotein machineries for almost all steps of its life cycle. The aim of this review is to summarize current knowledge concerning the interplay between HCV and lipoprotein metabolism. We discuss the role played by members of lipoproteins in HCV entry, replication and virion production.Germana Grassi Giorgia Di Caprio Gian Maria Fimia Giuseppe Ippolito Marco Tripodi Tonino Alonzi 2016World Journal of Gastroenterology2016,22,6:3
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