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| 1 | MicroRNA let-7b targets important cell cycle molecules in malignant melanoma cells and interferes with anchorage-independent growth显示文摘一幅 microRNA 表示屏幕被执行从良性的 melanocytic nevi 在 laser-microdissected 纸巾分析 157 不同 microRNAs (n = 10 ) 并且主要恶意的黑瘤(n = 10 ) ,用量的即时 PCR。微分表示被作出对有利的裁决 72 microRNAs。microRNAs 的 let-7 家庭的成员是显著地, down 作为与良性的 nevi 相比在主要黑瘤调整了,为是的这些分子的一个可能的角色暗示肿瘤在恶意的黑瘤压制 ors。有趣地,类似的调查结果为肺和结肠癌被描述了。在黑瘤房间试管内 down 的 let-7b 的 Overexpression 调整了 cyclins 的表示 D1, D3,和 A,和 cyclin 依赖的 kinase (Cdk ) 4,所有哪个被描述了在黑瘤开发起一个作用。蛋白质表示上的 let-7b 的效果由于单个 mRNAs 的 3'-untranslated 区域(3'UTRs ) 指向,为 cyclin D1 由记者基因分析例示。与它细胞周期管理者上的 down modulating 效果一致, let-7b 禁止了细胞周期前进和黑瘤细胞的抛锚无关的生长。总起来说,这些调查结果不仅指向早黑瘤开发的新规章的机制,而且可以打开大街因为未来指向了这个肿瘤的治疗。 | Julia Schultz Peter Lorenz Gerd Gross Saleh Ibrahim Manfred Kunz | 2008 | Cell Research2008，18，5： | 45 |
| 2 | 大别超高压变质带的进变质、超高压和退变质时代的准确限定:以双河大理岩中榴辉岩锆石SHRIMP U-Pb定年为例显示文摘在大别超高压变质带的双河地区存在一种特殊类型的榴辉岩,该类榴辉岩主要以似层状、条带状以及不规则透镜体赋存于大理岩中。矿物组成主要为石榴石、绿辉石以及少量的金红石、白云石、菱镁矿等。沿石榴石和绿辉石边缘常退变为角闪石+斜长石等,有的岩石完全退变为斜长角闪岩。激光拉曼和阴极发光综合分析表明,该类榴辉岩中的锆石可划分为两种类型:继承性碎屑锆石和变质锆石。继承性碎屑锆石十分少见,阴极发光图象具有明显的双层结构,即强发光的核和弱发光的边,核部和边部的包体矿物分别为Pl+Ap和Qtz+Pl。SHRIMP U-Pb定年结果表明。继承性碎屑锆石核部记录的207Pb/206Pb年龄为2701±15Ma,Th/U比值明显偏高为1.05,稀土元素配分模式显示重稀土明显富集,具有典型岩浆结晶锆石的特点;边部记录的207Pb/206Pb年龄为1801±12Ma-1753±22Ma,Th/U比值则明显偏低,为0.19-0.22之间,稀土元素配分模式显示重稀土相对平坦,具有典型变质锆石的特点。上述特征表明该类继承性碎屑锆石可能来源于太古代的基底,并经历了早元古代变质热事件的改造。新生的变质锆石无论是矿物包体还是阴极发光图象均与继承性碎屑锆石存在明显差异。有的变质增生锆石具有弱发光的核(阴极发光图象呈灰色)和强发光的边(阴极发光图象呈白色)。核部包体矿物组合为Qtz +Grt+Omp+Phe+Dol+Ap,具有典型石英榴辉岩相矿物组合特征,而边部则保存含柯石英的超高压包体矿物组合Coe+Grt +Omp+Mgs+Arg+Ap,表明该类锆石的核部和边部分别形成于俯冲进变质阶段和超高压变质阶段。另一部分变质增生锆石具有强发光的核(阴极发光图象呈白色)和弱发光的边(阴极发光图象呈黑色)。核部保存的标志性超高压包体矿物组合为Coe+Grt+Omp+Mgs+Arg+Ap,边部则保存Qtz+Cal等退变矿物组合,有的则缺乏矿物包体,表明该类锆石自超高压变质阶段开始生长,并经历了后期退变质作用的改造。从不同微区矿物包体组合的性质及其转变特征可以明显看出,自石英榴辉岩相进变质阶段到超高压峰期变质阶段存在下列转变反应:Qtz→Coe和Dol→Mgs+Arg;而自超高压峰期变质阶段到后期退变质阶段则存在下列退变反应:Coe→Qtz和Arg→Cal。SHRIMP U-Pb定年结果表明,含石英榴辉岩相矿物包体的锆石微区记录的206Pb/238U年龄为249-241Ma,加权平均值为244±4Ma,代表了深俯冲石英榴辉岩相进变质阶段的变质年龄;含柯石英等超高压矿物包体的锆石微区记录的206Pb/238U年龄为239-231Ma,加权平均值为234±3Ma,代表超高压阶段的峰期变质年龄;而含石英和方解石的退变边记录的206Pb/238U年龄为219-211Ma,加权平均值为216±6Ma,应代表后期折返阶段的角闪岩相退变质年龄。上述两类变质增生锆石微区的Th/U比值和稀土元素配分模式十分相似,Th/U比值变化于0.02- 0.18之间,稀土元素配分模式显示重稀土相对平坦,稀土元素总量明显低于继承性碎屑锆石,具有典型变质锆石的特点。根据锆石微区矿物包体的化学成分,采用Grt-Omp和Grt-Omp-Phe温压计,结合前人的变质反应实验资料的综合分析,确定榴辉岩的原岩在深俯冲过程的石英榴辉岩相进变质阶段的变质温压条件为T=588-668℃,P=1.7-1.8GPa;超高压峰期阶段的温压条件为T=784-849℃,P>5.5GPa;而构造折返过程中角闪岩相退变质阶段的温压条件为T=550-720℃,P=0.8~1.4GPa。由此可见,大别超高压变质岩的原岩——元古代(部分可能为太古代)的陆壳物质在早三叠纪发生俯冲至55- 60km深处,并经历了石英榴辉岩相变质作用。随后这些变质岩石继续深俯冲至165~175km的地幔深处,于中三叠纪发生了超高压变质作用,石英榴辉岩相矿物组合转变为超高压榴辉岩相矿物组合。最后这些超高压变质岩石发生构造折返,至晚三叠纪抬升到约30km的中下地壳深度,并经历了角闪岩相退变质作用的改造,超高压榴辉岩相矿物组合退变为角闪岩相矿物组合。由此推断,大别超高压变质带俯冲和折返速率分别为11-12km Myr-1和7.5-8.1km Myr-1。该项成果不仅确定了大别超高压变质地体的石英榴辉岩相进变质-超高压榴辉岩相峰期变质-角闪岩相退变质的年代谱系,而且对于重塑大别超高压变质地体的快速俯冲-折返的动力学模式有着重要的科学意义。 | 刘福来 薛怀民 许志琴 梁风华 Axel Gerdes | 2006 | 岩石学报2006，22，7： | 39 |
| 3 | 快速节俭启发式——基于有限理性和生态理性的简单决策规则显示文摘本文阐述了德国“马克斯 普朗克人类发展研究所”以GerdGigerenzer教授为代表的“适应行为与认知中心”简称“ABC研究中心 (组 )”关于判断、推理和决策制定简单启发式研究的理论背景、研究思路和技术路线 ,着重介绍了该研究中心在有限理性和生态理性假设基础上提出的一系列极富创意的快速节俭启发式规则 。 | 刘永芳 Gerd Gigerenzer Peter M.Todd | 2003 | 心理科学2003，26，1： | 30 |
| 4 | Increased susceptibility for intrahepatic cholestasis of pregnancy and contraceptive-induced cholestasis in carriers of the 1331T>C polymorphism in the bile salt export pump显示文摘AIM: To study the association of three common ABCB11 and ABCC2 polymorphisms (ABCB11: 1331T>C V444A; ABCC2: 3563T>A V1188E and 4544G>A C1515Y) with intrahepatic cholestasis of pregnancy (ICP) and contraceptive-induced cholestasis (CIC). METHODS: ABCB11 and ABCC2 genotyping data were available from four CIC patients and from 42 and 33 ICP patients, respectively. Allele-frequencies of the studied polymorphisms were compared with those in healthy pregnant controls and Caucasian individuals. Furthermore, serum bile acid levels were correlated with the presence or absence of the 1331 C allele.RESULTS: The ABCB11 1331T>C polymorphism was significantly more frequent in cholestatic patients than in pregnant controls: C allele 76.2% (CI, 58.0-94.4) vs 51.3% (CI 35.8-66.7), respectively (P = 0.0007); and CC allele 57.1% (CI 36.0-78.3) vs 20% (CI 7.6-32.4), respectively (P = 0.0065). All four CIC patients were homozygous carriers of the C allele. In contrast, none of the studied ABCC2 polymorphism was overrepresented in ICP or CIC patients. Higher serum bile acid levels were found in carriers of the 1331CC genotype compared to carriers of the TT genotype.CONCLUSION: Our data support a role for the ABCB11 1331T>C polymorphism as a susceptibility factor for the ←←← development of estrogen-induced cholestasis, whereas no such association was found for ABCC2. Serum bile acid and γ-glutamyl transferase levels might help to distinguish ABCB4- and ABCB11-related forms of ICP and CIC. | Yvonne Meier Tina Zodan Carmen Lang Roland Zimmermann Gerd A Kullak-Ublick Peter J Meier Bruno Stieger Christiane Pauli-Magnus | 2008 | World Journal of Gastroenterology2008，14，1： | 20 |
| 5 | Zoned Zircon from Eclogite Lenses in Marbles from the Dabie-Sulu UHP Terrane,China: A Clear Record of Ultra-deep Subduction and Fast Exhumation显示文摘摘要:在从 Dabie-Sulu 的云石的 Eclogite 透镜超离频压力(UHP ) 岩层是深深地 subducted 元沉积的岩石。在这些岩石中的锆石被用来抑制年龄与其他天体作同方并且 UHP 变态在 subduction 期间,并且以后后退变态在发掘期间。继承(由岩屑形成) 并且变形锆石根据播送轻显微镜学,阴极射线发光(CL ) 成像,踪迹元素内容和矿物质包括被区分。矿物质包括的分发与变形锆石的 CL 成像结合了使联系锆石地区(领域) 到不同变形舞台可能。域 1 由组成圆,长方形和细长纤弱的核心与黑暗光想象,并且包含石英 eclogite 外形矿物质包括集合,显示的形成在下面高压(HP ) T = 的变形条件 | LIU Fulai A. GERDES P. T. ROBINSON XUE Huaimin YE Jianguo | 2007 | Acta Geologica Sinica(English Edition)2007，81，2： | 18 |
| 6 | 纳米定位测量机操作测量结果(英文)显示文摘伊尔梅瑙工业大学过程测量和传感技术研究所研制了三维纳米定位和测量机 (NPMM ) .阿贝无偏设计使得该机器异常精确 .在整个 2 5mm× 2 5mm× 5mm的定位和测量域内 ,干涉测长系统分辨力可达 0 .1nm ,不确定度达 5~ 10nm .提供了纳米定位测量机的基本信息 ,介绍其操作模式 。 | JAGER Gerd GRUNWALD Rainer MANSKE Eberhard HAUSOTTE Tino FUβL Roland | 2004 | 纳米技术与精密工程2004，2，2： | 14 |
| 7 | High order aberration and straylight evaluation after cataract surgery with implantation of an aspheric,aberration correcting monofocal intraocular lens显示文摘·AIM: To evaluate the quality of vision in respect to high order aberrations and straylight perception after implantation of an aspheric, aberration correcting,monofocal intraocular lens(IOL).·METHODS: Twenty-one patients(34 eyes) aged 50 to83 y underwent cataract surgery with implantation of an aspheric, aberration correcting IOL(Tecnis ZCB00,Abbott Medical Optics). Three months after surgery they were examined for uncorrected(UDVA) and corrected distance visual acuity(CDVA), contrast sensitivity(CS)under photopic and mesopic conditions with and without glare source, ocular high order aberrations(HOA, Zywave II) and retinal straylight(C-Quant).· RESULTS: Postoperatively, patients achieved a postoperative CDVA of 0.0 log MAR or better in 97.1% of eyes. Mean values of high order abberations were +0.02±0.27(primary coma components) and-0.04 ±0.16(spherical aberration term). Straylight values of the C-Quant were 1.35±0.44 log which is within normal range of age matched phakic patients. The CS measurements under mesopic and photopic conditions in combination with and without glare did not show any statistical significance in the patient group observed(P ≥0.28).· CONCLUSION: The implantation of an aspherical aberration correcting monofocal IOL after cataractsurgery resulted in very low residual higher order aberration(HOA) and normal straylight. | Florian T A Kretz Tamer Tandogan Ramin Khoramnia Gerd U Auffarth | 2015 | International Journal of Ophthalmology(English edition)2015，8，4： | 14 |
| 8 | Aquaporin-8 expression is reduced in ileum and induced in colon of patients with ulcerative colitis显示文摘AIM: To study susceptibility genes which may play a potential role in the pathogenesis and etiology of inflammatory bowel disease (IBD). METHODS: To identify potential susceptibility genes we performed global gene expression profiling in patients with IBD and control specimens. For determination of an intrinsic gene expression profile in ulcerative colitis (UC) and Crohn’s disease (CD) compared to normal subjects, mucosal biopsies of non-inflamed regions of the colon and the terminal ileum were subjected to DNA microarray analysis. Real-time RT-PCR and immunohistochemistry were used for verification of selected regulated candidate genes and a genetic analysis was performed. RESULTS: We could show that aquaporin-8 (AQP8) mRNA and protein levels were significantly increased in the colon of UC patients compared to controls. Genetic analysis of the six exons and the promoter region of AQP8, however, revealed no mutations or polymorphisms in IBD patients. CONCLUSION: Our results suggest that upregulation of AQP8 in the colon of UC patients represents a secondary phenomenon which may, due to altered water exchange of the distal intestinal mucosa, disturb the physiologic colonic mucus barrier and thus lead to chronic infla- mmation and ulceration. | Alexandra Zahn Christoph Moehle Thomas Langmann Robert Ehehalt Frank Autschbach Wolfgang Stremmel Gerd Schmitz | 2007 | World Journal of Gastroenterology2007，13，11： | 13 |
| 9 | 基于双频正交光栅一维相移的相位测量偏折术研究显示文摘提出一种新的相移方法,该方法将原独立的水平和垂直一维正弦光栅集成为单幅正交正弦光栅图,再采用双频光栅相移方法,从而实现仅通过某一特定方向相移即可获取两正交相位分布,并进而计算出待测面的梯度分布并由梯度分布恢复待测表面面形。详细介绍了双频光栅相移方法,推导了相移方向与双频光栅相移的对应关系。在传统方法中,须独立投影或显示水平和垂直一维正弦光栅,且分别进行相移测量,因此共需2×N幅图像(N≥3);而在双频正交光栅相移方法中,最少需要5幅图像。当采用机械相移时,传统方法需要二维相移机构,而该方法仅需一维相移机构,因此该方法具有成本低、测量速度快、结构简单等优点。实测的眼镜片结果,验证了该方法的可行性。 | 刘元坤 Evelyn Olesch 杨征 Gerd Hausler 苏显渝 | 2015 | 中国激光2015，42，3： | 13 |
| 10 | Exogenous sphingomyelinase causes impaired intestinal epithelial barrier function显示文摘AIM: To test the hypothesis that hydrolysis of sphingomyelin to ceramide changes the composition of tight junctions (TJs) with increasing permeability of the intestinal epithelium. METHODS: Monolayers of Caco-2 cells were used as an in vitro model for the intestinal barrier. Permeability was determined by quantifi cation of transepithelialflux and transepithelial resistance. Sphingolipid-rich membrane microdomains were isolated by a discontinuous sucrose gradient and characterized by Western-blot. Lipid content of microdomains was analysed by tandem mass spectrometry. Ceramide was subcellularly localized by immunofluorescent staining.RESULTS: Exogenous sphingomyelinase increased transepithelial permeability and decreased transepithelial resistance at concentrations as low as 0.01 U/mL. Lipid analysis showed rapid accumulation of ceramide in the membrane fractions containing occludin and claudin-4, representing TJs. In these fractions we observed a concomitant decrease of sphingomyelin and cholesterol with increasing concentrations of ceramide. Immunofluorescent staining confirmed clustering of ceramide at the sites of cell-cell contacts. Neutralization of surface ceramide prevented the permeability-increase induced by platelet activating factor. CONCLUSION: Our findings indicate that changes in lipid composition of TJs impair epithelial barrier functions. Generation of ceramide by sphingomyelinases might contribute to disturbed barrier function seen in diseases such as inflammatory, infectious, toxic or radiogenic bowel disease. | Jürgen Bock Gerhard Liebisch Joachim Schweimer Gerd Schmitz Gerhard Rogler | 2007 | World Journal of Gastroenterology2007，13，39： | 11 |
| 11 | 多球果型马尾松的形态和生殖生物学特征研究显示文摘本文对多球果型马尾松和常见型马尾松在生长状态、形态结构、生殖发育等方面的差异进行研究和分析。在多球果型马尾松雌性生殖枝上 ,能够着生 4 0~ 80个球果 (大孢子叶球 ) ,有的甚至可以达到 1 93个以上。而在常见型马尾松的雌性生殖枝上 ,通常只着生有 1~ 8个球果 ,最常见的是着生 2~ 4个球果。多球果型马尾松和常见型马尾松在雌球花的芽组织结构和雌球花的分化过程中有着明显的差异。通过显微分析我们发现 :多球果型马尾松雌球花原基的发育在当年生过冬顶芽的下部 ,在它的上部 ,还发育有一系列的营养芽原基 (1 0列以上 )。而常见型马尾松雌球花原基的发育在当年生过冬顶芽的顶端。雌球花发育机理的不同 ,决定了多球果型马尾松球果的着生部位发生了变异。多球果型马尾松球果着生在春梢的下 (基 )部 ,常见型马尾松球果着生在春梢的顶部。多球果型马尾松与常见型马尾松球果 (大孢子叶球 )的发育过程和发育起始时间不相同。通过对 8~ 1 2月标本进行显微切片分析 ,多球果型马尾松球果的发育起始时间在当年的 8月 (过冬顶芽开始形成的同时 ) ,与小孢子叶球的发育起始时间同步。常见型马尾松球果的发育起始时间是当年的 1 1月 ,两种类型马尾松的大孢子叶球都是在次年 4月受粉 ,到第三年的 1 | 王孜昌 Gerd hause 邓伦秀 王宏艳 刘开跃 任志得 江艺 徐涵 | 2004 | 种子2004，23，7： | 10 |
| 12 | Ephrin-B2 is differentially expressed in the intestinal epithelium in Crohn's disease and contributes to accelerated epithelial wound healing in vitro显示文摘AIM: Eph receptor tyrosine kinases and their membrane bound receptor-like ligands, the ephrins, represent a bi-directional cell-cell contact signaling system that directs epithelial movements in development. The meaning of this system in the adult human gut is unknown. We investigated the Eph/ephrin mRNA expression in the intestinal epithelium of healthy controls and patients with inflammatory bowel disease (IBD).METHODS: mRNA expression profiles of all Eph/ephrin family members in normal small intestine and colon were established by real-time RT-PCR. In addition, differential expression in IBD was investigated by cDNA array technology, and validated by both real-time RT-PCR and immunohistochemistry. Potential effects of enhanced EphB/ephrin-B signaling were analyzed in an in vitro IEC-6 cell scratch wound model.RESULTS: Human adult intestinal mucosa exhibits a complex pattern of Eph receptors and ephrins. Beside the known prominent co-expression of EphA2 and ephrinA1,we found abundantly co-expressed EphB2 and ephrin-B1/2.Interestingly, cDNA array data, validated by real-time PCR and immunohistochemistry, showed upregulation of ephrin-B2 in both perilesional and lesional intestinal epithelial cells of IBD patients, suggesting a role in epithelial homeostasis. Stimulation of ephrin-B signaling in ephrinB1/2 expressing rat IEC-6-cells with recombinant EphB1Fc resulted in a significant dose-dependent acceleration of wound closure. Furthermore, fluorescence microscopy showed that EphB1-Fc induced coordinated migration of wound edge cells is associated with enhanced formation of lamellipodial protrusions into the wound, increased actin stress fiber assembly and production of laminin at the wound edge.CONCLUSION: EphB/ephrin-B signaling might represent a novel protective mechanism that promotes intestinal epithelial wound healing, with potential impact on epithelial restitution in IBD. | Christian Hafner Stefanie Meyer Thomas Langmann Gerd Schmitz Frauke Bataille Ilja Hagen Bernd Becker Alexander Roesch Gerhard Rogler Michael Landthaler Thomas Vogt | 2005 | World Journal of Gastroenterology2005，11，26： | 9 |
| 13 | 人非理性且难教化? 论支持自由家长主义的证据显示文摘基于心理学的研究,自由家长主义者认为人们的思维有个体难以克服的、根深蒂固的系统性缺陷,并难以通过教育来避免和消除,因此主张因势利导,仰仗外部专家的'助推'把人们的行为引导到正确方向。然而,从生态理性的角度看,人们依照自由家长主义者所谓的认知偏差做出的选择未必导致糟糕的结果,而依照自由家长主义者所推崇的理性方法做出的选择也未必导致理想的结果。本文分析了自由家长主义者用来支持助推的证据后发现:(1)它们源于一些研究者对'何为理性'的狭隘定义,误解了人类理性的本质;(2)它们对研究结果进行了选择性的报告,忽视了与这些证据相反的证据。通过这些分析,我们认为'人非理性且难教化'这一自由家长主义者的论断过于武断并有失偏颇。投入教育,教会人们如何精明老练地处理风险不仅是可行的,而且是替代助推的一个更为持久有效的解决方案。 | Gerd Gigerenzer 栾胜华 刘永芳 | 2019 | 心理学报2019，51，4： | 8 |
| 14 | Simultaneous monitoring of PCB profiles in the urban air of Dalian,China with active and passive samplings显示文摘The concentration of polychlorinated biphenyls (PCBs) in the urban air of Dalian, China was monitored from November 2009 to October 2010 with active high-volume sampler and semipermeable membrane device (SPMD) passive sampler. The concentration of PCBs (particle + gas) ( ∑ PCBs) ranged from 18.6 to 91.0 pg/m 3 , with an average of 50.9 pg/m 3 , and the most abundant dioxin-like PCB (DL-PCBs) was PCB118. The WHO-TEQ values of DL-PCBs were 3.6-22.1 fg/m3 , with an average of 8.5 fg/m 3 , and PCB126 was the maximum contributor to ∑ TEQ. There was a much larger amount of PCBs in the gas phase than in the particulate phase. The dominant PCB components were lower and middle molecular weight PCBs. With increasing chlorination level, the concentration of the PCB congeners in the air decreased. The gas-particulate partitioning of PCBs was different for the four seasons. The gas- particulate partitioning coefficients (logK p ) vs. subcooled liquid vapor pressures (logP L 0 ) of PCBs had reasonable correlations for different sampling sites and seasons. The absorption mechanism contributed more to the gas-particulate partitioning process than adsorption. Correlation analysis of meteorological parameters with the concentration of PCBs was conducted using SPSS packages. The ambient temperature and atmospheric pressure were important factors influencing the concentration of PCBs in the air. The distribution pattern of the congeners of PCBs and the dominant contributors to DL-PCBs and TEQ in active samples and SPMDs passive samples were similar. SPMD mainly sequestrated gas phase PCBs. | Qian Xu Xiuhua Zhu Bernhard Henkelmann Karl-Werner Schramm Jiping Chen Yuwen Ni Wei Wang Gerd Pfister Jun Mu Songtao Qin Yan Li | 2013 | Journal of Environmental Sciences2013，25，1： | 8 |
| 15 | 术中二维相干光断层扫描作为前节手术的一个新工具显示文摘我们测试了1310nm相干光断层扫描仪与手术显微镜前部镜头的分光镜连接后对前节手术过程中术中的非接触性成像。这项对相干光断层成像技术的新改进可完成前节手术术中角膜、巩膜的高分辨率横断面的成像与厚度测量。其在板层切开技术如深层前板层角膜移植术和小梁切除术中尤为有用。 | Gerd Geerling Maya Müller Christian Winter Hans Hoerauf Stefan Oelckers Horst Laqua Reginald Birngruber 李晓宁(译) 任泽钦(校) | 2005 | 美国医学会眼科杂志(中文版)2005，17，4： | 7 |
| 16 | INFLUENCE OF AIR HUMIDITY ON THE SUPPRESSION OF FUGITIVE DUST BY USING A WATER-SPRAYING SYSTEM显示文摘One of the main origins of fugitive dust emission arises from bulk handling in quarries or mines, in par- ticular, from bulk materials falling from a hopper or a conveyor belt. Water-spraying systems, using two-phase nozzles, are one of the methods to suppress such dust emission. In this work we tried to develop a mathematical model to cor- relate air humidity, water flux through the nozzle and the dust (in particular PM10) emission, in order to improve the ap- plication and efficiency of these systems. Sand from the Yellow River in China was dropped from a conveyor belt into a dust chamber at 1 kg?min-1, wherefrom the emitted dust was sucked off and quantified via a cascade impactor. A two-phase nozzle was installed in the dust chamber with a water flux through the nozzle of 1.2 to 3 L?h-1, whereas the relative air humidity changed between 55 and 73%. Dust emission was found to be linearly dependent on relative air humidity. Furthermore model equations were developed to describe the dependence of PM10 emission on water flux and relative air humidity. | Peter Werner Grundnig Wilhelm Hoeflinger Gerd Mauschitz Zechang Liu Guiqin Zhang Zhiqiang Wang | 2006 | China Particuology2006，4，5： | 6 |
| 17 | 复碱化混凝土孔溶液的pH值(英文)显示文摘碳化混凝土的复碱化是用碳酸钙缓冲溶液浸渍混凝土的电化学过程,目的是使混凝土孔溶液的pH值稳定在10以上,从而防止混凝土的进一步碳化.然而,该方法的实际应用表明:虽然孔溶液中已明显含有足量的碱(Na+,K+,Li+),但pH值仍降到10以下.本文通过试验提出了一个用以解释pH值随时间降低的假说,结果表明:由于混凝土孔溶液中存在溶解的硫酸盐,因此单纯提高孔溶液的碱离子(碳酸盐)相对含量,不能确保其pH值高于10.用提出的化学机理可解释混凝土电化学复碱化技术实际应用中观察到的现象,但是,由于混凝土孔溶液中溶解离子相互作用十分复杂,目前还不能在复碱化技术中对其加以考虑,因此复碱化技术尚不能被进一步推荐应用. | A. Gerdes F. H. Wittmann | 2003 | 建筑材料学报2003，6，2： | 6 |
| 18 | VACOMASS~曝气控制系统实现污水处理厂节能降耗和自动化控制显示文摘VACOMASS系统是是由德国Binder公司开发的一套污水处理厂生物池精确曝气控制系统,不但提升污水厂的自动化控制水平,而且能有效降低污水厂的能耗和运行费用,在欧洲已得到了广泛应用。为验证该系统在国内的适用性,绍兴污水处理厂联合德国Binder公司对VACOMASS系统开展了生产性对照实验测试。实验结果表明,VACOMASS曝气控制系统能有效稳定生物池的溶解氧浓度,提高了生物池的自动化控制水平:该系统使生物池的溶解氧稳定在设定值±0.3mg/l,生物池溶解氧浓度波动极小;而对照组溶解氧极不稳定,最低为1.5mg/l,最高为5.9mg/l,影响了生物池污染物的去除效率的稳定性。进一步的实验结果表明,VACOMASS曝气控制系统的应用节省了20.7%的曝气量,有力的节省了曝气能耗费用。目前,VACOMASS曝气控制系统已在绍兴污水处理厂三期得到全面应用,初步调试已于2008年8月完成,预计2008年12月完成验收。 | Gerd Rishe 蔡芝斌 尚爱安 高陆令 陶薇 | 2009 | 水工业市场2009，，3： | 6 |
| 19 | Autoantibodies against G-Protein-Coupled Receptors Modulate Heart Mast Cells显示文摘Mast cells are believed to be involved in myocardial tissue remodelling under pathophysiological conditions. We examined the effects of autoantibodies against G-protein-coupled receptors in sera of patients with heart diseases on myocardial mast cells in the cultured neonatal Sprague-Dawley rat heart cells. Cells collected at day 3 and 10 of the culture were preincubated with autoantibodies against α1-adrenoceptor and angiotensin II AT1-receptor, agonist phenylephrine and angiotensin II, and control IgG. The pretreated cultured cells were stained for selected mast cell markers tryptase, chymase and TNF-α. The cultured cells were also processed for observation with electron microscopy. The autoantibodies-treatment of the 3-day cultured cells caused both increased intensity of immunofluorescence (p < 0.05) and their enlarged diameters of the mast cells when compared to age-matched ones. In contrast, the fluorescence of preincubated 10-day-old mast cells was decreased compared with controls (p < 0.01). In control samples, the fluorescence of 10-day-old mast cells was significantly higher than that of 3-day-old ones (p < 0.001). Results of electron microscopy examination demonstrated there was an increased granulation of treated 3-day-old mast cells, while a degranulation of mast cells at day 10 of application. The results suggest the modulation effect of the autoantibodies against G-protein-coupled receptors on mast cells, indicating a potential functional link between the autoantibodies against G-protein-coupled receptors and the mast cells in progression of heart disease. | Ludmila Okruhlicova Rosemarie Morwinski Wolfgang Schulze Sabine Bartel Peter Weismann Narcisa Tribulova Gerd Wallukat | 2007 | Cellular & Molecular Immunology2007，4，2： | 6 |
| 20 | 工业粉体下落过程粉尘排放特性的实验研究显示文摘根据与维也纳工业大学化学工程研究所共同确定的实验方案,在实验室开发并设计了一套自由下落装置,研究粉体下落过程中粉尘的排放特性。通过实验主要测定下落高度、空气湿度和质量流量对粉尘排放的影响。实验结果表明,下落高度和空气湿度对粉尘排放均有影响,且空气湿度对粗粒子的排放影响较大,对细粒子影响较小;随着质量流量的增加,粉尘产生率逐渐减小,但质量流量的增加也会增加粉尘浓度,加重了对工人的危害。建立了影响因素与粉尘产生率之间的数学模型,经检验,二者之间存在显著相关,实测值与理论计算值基本一致,可以应用已建立的数学模型定量评价粉尘产生量。 | 张桂芹 刘泽常 李敏 Wilhelm Hoeflinger Gerd Mauschitz | 2006 | 环境科学与技术2006，29，11： | 6 |
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