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| 1 | 前庭康复网络干预对老年慢性头晕患者的效果:一项英国社区医疗机构开展的随机对照试验显示文摘目的前庭康复治疗对由前庭功能障碍所致的眩晕来说比较有效,但迄今为止这种康复治疗的开展还较少。本研究旨在探讨前庭康复网络干预项目在社区老年慢性头晕患者中的效果。方法本项为单中心、单盲的随机对照试验,在英格兰南部54家社区医疗机构开展。研究对象为来自这些机构的年龄≥50岁、患有眩晕并头部运动眩晕加重的患者。患者被随机分为干预组和普通治疗组。干预组给予前庭康复网络干预[平衡训练(患者通过网络学习前庭康复训练及认知行为管理策略),详细内容见http://gffzz647ebb38d6614268sqofw0n0u5nfu60xc.ffgz.tsg.suse.edu.cn],普通治疗组给予普通全科治疗。在干预前、干预3个月及6个月后,采用简明眩晕症状量表(VSS-SF)对患者的眩晕程度进行调查。干预效果的主要评估指标为干预6个月后的VSS-SF分数。结果共纳入296例患者,其中66%为女性,中位年龄为67岁。250例(84%)患者在干预3个月后完成了VSS-SF测评,230例(78%)患者在干预6个月后完成了VSS-SF测评。干预3个月后,干预组VSS-SF分数比普通治疗组低2.75分[95%CI(1.39,4.12),P<0.001];干预组眩晕残障程度分数比普通治疗组低6.15分[95%CI(2.81,9.49),P<0.001]。干预6个月后,干预组VSS-SF分数比普通治疗组低2.26分[95%CI(0.39,4.12),P=0.020];干预组眩晕残障程度分数比普通治疗组低5.58分[95%CI(1.19,10.0),P=0.010]。结论在没有临床支持的情况下,前庭康复网络干预可使社区老年慢性头晕患者眩晕及眩晕残障程度有所降低。这种康复治疗可在社区医疗机构中广泛应用。 | GERAGHTY A W A ESSERY R KIRBY S 本刊编辑部 | 2017 | 中国全科医学2017，20，28： | 10 |
| 2 | Consideration of corneal biomechanics in the diagnosis and management of keratoconus: is it important?显示文摘Keratoconus is a bilateral,non-inflammatory,degenerative corneal disease.The occurrence and development of keratoconus is associated with corneal thinning and conical protrusion,which causes irregular astigmatism.With the disruption of the collagen organization,the cornea loses its shape and function resulting in progressive visual degradation.Currently,corneal topography is the most important tool for the diagnosis of keratoconus,which may lead to false negatives among the patient population in the subclinical phase.However,it is now hypothesised that biomechanical destabilisation of the cornea may take place ahead of the topographic evidence of keratoconus,hence possibly assisting with disease diagnosis and management.This article provides a review of the definition,diagnosis,and management strategies for keratoconus based on corneal biomechanics. | FangJun Bao Brendan Geraghty QinMei Wang Ahmed Elsheikh | 2016 | Eye and Vision2016，3，1： | 8 |
| 3 | Adenomatous polyposis coli and translational medicine显示文摘 | James Geraghty | 1996 | 1996 (9025)1996，，9025： | 3 |
| 4 | A second lineage of mammalian major histocompatibility complex class I genes 显示文摘 | Bahram S Bresnahan M Geraghty DE | 1994 | Proe Natl Acad Sci USA1994，91，： | 1 |
| 5 | The clinical signi ficance of axillary lymph node micrometastases in breast cancer显示文摘 | Sakorafas GH Geraghty J Pavlakis G | 2004 | Eur J Surg Oncol2004，30，8： | 1 |
| 6 | ABCD2 score predicts severity rather than risk of early recurrent events af- ter transient ischemic attack显示文摘 | Chandratheva A Olivia C Geraghty | 2010 | Stroke2010，41，： | 1 |
| 7 | Effect of capsaicin and dihydrocapsaicin on in vitro blood coagulation and platelet aggregation显示文摘 | ADAMS M J AHUJA K D K GERAGHTY D P | | 0，，06： | 1 |
| 8 | Adenomatous polyposis coil and translational medicine显示文摘 | Geraghty J | 1996 | Lancet1996，348，9025： | 1 |
| 9 | Multiple molecular mechanisms underlying subdiagnostic variants of Marfan syndrome 显示文摘 | Montgomery RA Geraghty MT Bull E | 1998 | Am J Hum Genet1998，63，6： | 1 |
| 10 | CT-guided transthoracic needle aspiration biopsy of pulmonary nodules:needle size and pneumothorax rate显示文摘 | Geraghty P R Kee S T McFarlane G et a1 | 2003 | Radiology2003，229，2： | 1 |
| 11 | Dose reduction in pediatric CT:a rational approach 显示文摘 | Boone JM Geraghty EM Seibert JA | 2003 | Radiology2003，228，2： | 1 |
| 12 | A review and comparison of hybrid and pull-type production control strategies显示文摘 | GERAGHTY J HEAVEY C | 2005 | OR Spectrum2005，27，23： | 1 |
| 13 | A soluble form of the HLA-G antigen is encoded by a messenger ribonucleic acid containing intron 4显示文摘 | Fujii T Ishitani A Geraghty DE | 1994 | J Immunol1994，153，： | 1 |
| 14 | Evidence forUreterorenoscopy and Laser Fragmentation (URSL) for Large Renal Stones in the Modem Era显示文摘 | Geraghty R Abourmarzouk O Rai B | 2015 | Curr Urol Rep2015，16，8： | 1 |
| 15 | Abdominal aortic aneurysms: basic mechanisms and clinical implications显示文摘 | Thompson RW Geraghty PJ Lee TK | 2002 | Curr Probl Surg2002，39，： | 1 |
| 16 | Adenomatous polyposis coli and translationalmedicine显示文摘 | Geraghty J | 1996 | Lancet1996，348，： | 1 |
| 17 | HLA-F surface expression on B cell and monocyte cell lines is partially independent from tapasin and completely independent from TAP显示文摘 | Lee N Geraghty DE | 2003 | J Immunol2003，171，10： | 1 |
| 18 | Denomatous polyposis coli and translational medi- cine显示文摘 | Geraghty JA | 1996 | Lancet1996，348，9025： | 1 |
| 19 | CT-guided transthoracic necdle aspiration biopsy of pulmonary nodules:needle aisle and pneumothorax rate显示文摘 | Geraghty PR Kee ST Mcfarlane G | | 0，，02： | 1 |
| 20 | Adenomatous polyposis coli and translational medicine显示文摘 | Geraghty J | | 0，，9025： | 1 |
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