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| 1 | Prediction of atrial fibrillation development and progression:current perspectives显示文摘Atrial fibrillation(AF) is the most common arrhythmia in clinical practice. Several conventional and novel predictors of AF development and progression(from paroxysmal to persistent and permanent types) have been reported. The most important predictor of AF progression is possibly the arrhythmia itself. The electrical, mechanical and structural remodeling determines the perpetuation of AF and the progression from paroxysmal to persistent and permanent forms. Common clinical scores such as the hypertension, age ≥ 75 years, transient ischemic attack or stroke, chronic obstructive pulmonary disease, and heart failure and the congestive heart failure, hypertension, age ≥ 75 years, diabetes mellitus, stroke/transient ischemic attack, vascular disease, age 65-74 years, sex category scores as well as biomarkers related to inflammation may also add important information on this topic. There is now increasing evidence that even in patients with so-called lone or idiopathic AF, the arrhythmia is the manifestation of a structural atrial disease which has recently been defined and described as fibrotic atrial cardiomyopathy. Fibrosis results from a broad range of factors related to AF inducing pathologies such as cell stretch, neurohumoral activation, and oxidative stress. The extent of fibrosis as detected either by late gadolinium enhancement-magnetic resonance imaging or electroanatomic voltage mapping may guide the therapeutic approach based on the arrhythmia substrate. The knowledge of these risk factors may not only delay arrhythmia progression, but also reduce the arrhythmia burden in patients with first detected AF. The present review highlights on the conventional and novel risk factors of development and progression of AF. | Konstantinos Vlachos Konstantinos P Letsas Panagiotis Korantzopoulos Tong Liu Stamatis Georgopoulos Athanasios Bakalakos Nikolaos Karamichalakis Sotirios Xydonas Michael Efremidis Antonios Sideris | 2016 | World Journal of Cardiology2016，8，3： | 16 |
| 2 | Efficacy and safety of novel anticoagulants in the elderly显示文摘Atrial 纤维性颤动和静脉的 thromboembolism (VTE ) 是与有害 thrombotic 事件联系的普通混乱,特别地在老病人。Polypharmacy,合作病态,和改变的 pharmacokinetics,在这些病人经常在场,使抗凝剂的使用变为相当挑战性。新奇口头的抗凝剂(NOAC ) 最近作为维生素 K 对手(VKA ) 的选择出现了并且主要因为他们的更少药和食物相互作用和容易使用,逐渐地正在增加他们的流行。他们的有效性和安全在一般人口是生长得很好的但是在利益和伤害在之间的平衡老仍然是不清楚的。在这些病人的平淡的使用是不平常的。积累的数据证明了 NOAC 的利益在所有年龄组之中是一致的,展示在阻止 thrombotic 事件的相等或更大的功效。过量流血与与 VKA 相比的 NOAC 是更低的,但是为模式放血在他们之中并且面对面是迥异的比较不是可得到的。在老人口的新奇抗凝剂的功效和安全上的现在的评论热点。 | Nikolaos Karamichalakis Stamatis Georgopoulos Konstantinos Vlachos Ioarmis Liatakis Michael Efremidis Antonios Sideris Konstantinos P Letsas | 2016 | Journal of Geriatric Cardiology2016，13，8： | 3 |
| 3 | Stochastic response surface methods for uncertainty propagation: application to environmental and biological systems 显示文摘 | Isulapalli S S Roy A Georgopoulos P G | 1998 | Risk Analysis1998，18，3： | 1 |
| 4 | Stochastic Response Surface Methods for Uncertainty Propagation: Application to Environmental and Biological System显示文摘 | Isulapalli S S Roy A Georgopoulos P G | 1998 | Risk Analysis1998，18，3： | 1 |
| 5 | Stochastic Response Surface Methods (SRSM) for Uncertainty Propagation: Application to Environmental and Biological Systems 显示文摘 | Isukapalli S S Roy A Georgopoulos P | 1998 | Risk Analysis1998，18，3： | 1 |
| 6 | Varying magnitude of GABAergic recurrent inhibition enhancement by different sedative/anesthetic agents in dorsal and ventral hippocampus 显示文摘 | Georgopoulos P Petrides T Kostopoulos G | 2008 | Brain Res2008，1207，： | 1 |
| 7 | Abolished circadian rhythm of salivary cortisol in elite artistic gymnasts 显示文摘 | Georgopoulos N A Rottstein L Tsekouras A The- odoropoulou A Koukkou E Mylonas P Polykarpou G Lampropoulou E Iconomou G Legise M Va- genakis A G Markou K B | 2011 | Steroids2011，76，5： | 1 |
| 8 | Thermoplastic polymers reinforced with fibrous agricultural residues 显示文摘 | S Th Georgopoulos P A Tarantili E Avgerinos etal | 2005 | Polymer Degradation and Stability2005，90，： | 1 |
| 9 | The short-term effect of latanoprost on intraocular pressure and pulsatile ocular blood flow显示文摘 | Georgopoulos GT Diestelhorst M Fisher R Ruokonen P Krieqlstein GK | 2002 | Acta Ophthalmol Scand2002，80，1： | 1 |
| 10 | Neuronal population coding of movement direction显示文摘 | GEORGOPOULOS A P SCHWARTZ A B KETTNER R E | 1986 | Science1986，233，4771： | 1 |
| 11 | Stochastic response sur- face methods (SRSMs) for uncertainty propagation: appli- cation to environmental and biological system显示文摘 | Isukapalli S S Georgopoulos P G | 1998 | Risk A- nalysis1998，18，3： | 1 |
| 12 | Phosphoryl- ation controls Ikaros's ability to negatively regulate the GI- S transition显示文摘 | G6mez-del Areo P Maki K Georgopoulos K | 2004 | Mol Cell Biol2004，24，7： | 1 |
| 13 | Stochastic response surface methods (SRSMs) for uncertainty propagation:application to environmental and biological systems显示文摘 | Isukapalli S S Roy A Georgopoulos P G | | 0，，03： | 1 |
| 14 | Thermoplastic polymers reinforced with fibrous agricultural residues显示文摘 | Georgopoulos S T Tarantili P A Avgerinos E | | 0，，02： | 1 |
| 15 | Stochastic re sponse surface methods for uncertainty propagation: ap plieation to environmental and biological systerns显示文摘 | Isulapalli S S Roy A Georgopoulos P G | 1998 | Risk Analysis1998，18，3： | 1 |
| 16 | Mechanistic Modeling of Emergency Events: Assessing the Impact of Hypothetical Releases of Anthrax 显示文摘 | S S IsukapaUi P J Lioy P G Georgopoulos | 2008 | Risk Analysis (S0272-4332)2008，28，3： | 1 |
| 17 | Stochastic Response Surface Methods for Uncertainty Propagation: Application to Environmental and Biological Systems 显示文摘 | Isulapalli S S Roy A Georgopoulos P G | 1998 | Risk Analysis1998，，3： | 1 |
| 18 | Gaussian Mixture Clustering and Imputation of Microarray Data显示文摘 | Ouyang M Welsh W J Georgopoulos P | 2004 | Bioinformatics2004，20，6： | 1 |
| 19 | Stochastic response surface methods for uncertainty propagation: application to environmental and biological systems 显示文摘 | Isulapalli S S Roy A Georgopoulos P G | 1998 | Risk Analysis1998，18，3： | 1 |
| 20 | Long - term alterations of respiratory function in adolescents wearing a brace for idiopathic scoliosis 显示文摘 | Korovessis P Filos KS Georgopoulos D | 1996 | Spine1996，17，： | 1 |
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