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89篇 您的检索式:作者名="Genzel"
    题名 作者 年代 出处 被引量
1Fatty acid composition of human milk during the 1st month after term and preterm delivery显示文摘Genzel BO Wahle J Koletzko B 1997Eur J Pediatr1997,156,:2
2基于MDCK悬浮细胞灌注培养的流感病毒生产过程开发显示文摘为了提升用MDCK悬浮细胞培养生产流感疫苗的效率,克服目前存在的产能低下问题,以期满足日益增长的流感疫苗市场需求和提升应对大流行爆发的能力。通过病毒驯化、稀释流加条件下的细胞生长和产毒能力分析、Semi-perfusion中的细胞高密度培养可行性分析以及ATF灌注反应器过程验证完成过程开发。驯化的病毒加速了其在细胞内的感染扩增,且在稀释流加培养中获得(3.57±0.17)log10(HAU/100μL)的病毒滴度。Semi-perfusion可实现细胞高密度培养至40×106 cells/mL以上,病毒产量达4 log10(HAU/100μL)以上,同时发现MOI和胰酶浓度对病毒的复制过程存在显著影响。在反应器中的ATF灌注培养过程得到了与Semi-perfusion相近的细胞密度及更高的病毒产量4.37 log10(HAU/100μL),并且通过降温措施维持了高密度下的单细胞病毒产量,克服了“细胞密度效应”。建立了基于MDCK悬浮细胞ATF灌注培养的流感病毒生产平台,通过同时提高细胞密度和单细胞病毒产率提升了流感病毒的生产效率,为基于细胞培养的流感疫苗产业化生产提供了新选择。吴熠潇 Thomas Bissinger Yvonne Genzel 刘旭平 Udo Reichl 谭文松 2020生物技术通报2020,36,10:2
3Wave microcarrier cultivation of MDCK cells for influenza virus production in serum containing and serumfree media 显示文摘Genzel Y Olmer R M Schiller B 2006Vaccine2006,24,:1
4Residual stress fields in surface- treated silicon carbide for space industry-comparison of biaxial and triaxial analysis using differebt X-ray methods显示文摘Genzel CH KLAUS M DENKS I 2005Materials Science and Engineering2005,390,:1
5A step towards the discrimination of beta-lactamase-producing clinical isolates of Enterobacteriaceae and Pseudomonas aeruginosa by MALDI-TOF mass spectrometry显示文摘SCHAUMANN R KNOOP N GENZEL GH 2012Med Sci Monit2012,18,9:1
6A step towards the dis- criminatian of heta-lactamese-produeing c/in/ca/ isolates of Enter- obacteriaceae and Pseudomonas aeruginosa by MALDI-TOF mass spectrometry显示文摘Schanmann R Knoop N Genzel GH 2012Med Sci Monit2012,18,9:1
7Occipitocervical fusion for rheumatoid arthritis using the inside-outside stabilization technique显示文摘Sandhu F A Pait T G Genzel E 2003S pine2003,28,4:1
8Optical absorption of small metallic particles 显示文摘KREIBIG U GENZEL L 1985Surface Science(S0039-6028)1985,156,2:1
9Optical absorption of small metallic particles 显示文摘KREIBIG U GENZEL L 1985Surface Sci1985,156,:1
10Residual stress analysis of diamond-coated WC-Co cutting tools:Separation of film and substrate information by grazing X-ray diffraction显示文摘Meixner M Klaus M Genzel Ch 2013J Appl Cryst2013,46,5:1
11Discrimination of En-terobacteriaceae and non-fermenting gram negative bacilli by MALDI-TOF mass spectrometry显示文摘Schaumann R Knoop N Genzel GH 0,,:1
12Hemisphere asymmtry in parasympathelic control of the heart显示文摘Wittling W Block A Genzel S 1998Neuropsychologia1998,36,:1
13A step toward a green chemistry preparation of enantiopure (S)-2-, -3-, and -4-pyridyloxirane via an epoxide hydrolase catalyzed kinetic resolution 显示文摘 Archelas A Broxterman QB 2001J Org Chem2001,66,:1
14Structure and kinematics of H20 sources in clusters of newly-formed OB stars 显示文摘GENZEL R DOWNES D MORAN J 1978A&A1978,66,:1
15Sex and modulatory menstrual cycle effects on sleep related memory consolidation 显示文摘Lisa Genzel Teresa Kiefer Lisa Renner 2012Psychoneuroendocrinology2012,37,7:1
16Model for long-wavelength optical phonon modes of mixed crystals显示文摘Genzel L Martin T P Perry C H 1974Physical Solid Status B1974,62,:1
17A new MDCK suspen- sion line cultivated in a fully defined medium in stirred - tank and wave bioreactor显示文摘LOHR V GENZEL Y BEHRENDT I 2010Vaccine2010,28,38:1
18Structure and kinematics of H2O sources in clusters of newly-formed OB stars 显示文摘Genzel R Downes D Moran J 1978A&A1978,66,:1
19Postnatal growth curves for extremely low birth weight infants with early enteral nutrition 显示文摘DIEKMANN M GENZEL BOROVICZENY O ZOPPELLI L 2005Eur J Pediatr2005,164,12:1
20In vivo osteogenesis assessment of a tricalcium phosphate paste and a tricalcium phosphate foam bone grafting materials 显示文摘LOPEZ-HEREDIA M A BARNEWITZ D GENZEL A 2014Key Engineering Materials2014,631,42:1
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