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3篇 您的检索式:作者名="Geng Mingwei"
    题名 作者 年代 出处 被引量
1One-pot formation and characterization of macrocyclic aromatic tetrasulfonates显示文摘Geng Mingwei Zhang Dechun Wu Xiangxiang 2009Org Lett2009,11,4:1
2One- pot formation and characterization of macrocyclic aromatic tetrasulfonates 显示文摘Geng Mingwei Zhang Dechun Wu Xiangxiang 2009Org Lett2009,11,4:1
3Intracerebroventricular transplanted bone marrow stem cells survive and migrate into the brain of rats with Parkinson's disease显示文摘In this study,6-hydroxydopamine was stereotaxically injected into the right substantia nigra compact and ventral tegmental area of rats to establish Parkinson's disease models.The rats then received a transplantation of bone marrow stromal cells that were previously isolated,cultured and labeled with 5-bromo-2'-deoxyuridine in vitro.Transplantation of the bone marrow stromal cells significantly de-creased apomorphine-induced rotation time and the escape latency in the Morris water maze test as compared with rats with untreated Parkinson's disease.Immunohistochemical staining showed that,5-bromo-2'-deoxyuridine-immunoreactive cells were present in the lateral ventricular wall and the choroid plexus 1 day after transplantation.These immunoreactive cells migrated to the surrounding areas of the lateral cerebral ventricle along the corpus callosum.The results indicated that bone marrow stromal cells could migrate to tissues surround the cerebral ventricle via the cerebrospinal fluid circulation and fuse with cells in the brain,thus altering the phenotype of cells or forming neuron-like cells or astrocytes capable of expressing neuron-specific proteins.Taken together,the present findings indicate that bone marrow stromal cells transplanted intracerebroventricularly could survive,migrate and significantly improve the rotational behavior and cognitive function of rats with experimentally induced Parkinson's disease.Ping Gu Zhongxia Zhang Dongsheng Cui Yanyong Wang Lin Ma Yuan Geng Mingwei Wang 2012Neural Regeneration Research2012,7,13:0
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