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| 1 | Theoretical framework of dualistic nature–social water cycle显示文摘The global climate change and intensification of human activities in recent decades have made profound changes in hydrological cycle processes and water resources,and produced serious water problems and water crisis in many areas.The main reason is that the driving force of water cycle,the structure of water cycle,and the parameters of water cycle have dualistically evolved under the influence of human activities,and consequently resulted in reduction of runoff water resources,water pollution,and degradation of natural ecosystems.In order to realize of the safety aim of water supply,water environment,and ecosystem in area which is short of water resources,scientific regulation of water resources must take basin water cycle system as the unified base,and the first scientific basis is the awareness of the internal mechanism and law of water cycle evolution under highly intensive human activities.This article discussed four aspects of dualistic water cycle evolution,including its history in China,its theory,its characteristics in a typical basin,and its description of integral structure,along with the conceptive model system to quantify it.This article can be a reference to the basic cognition of water cycle evolution in a changing environment,and the study of water resources reduction reasons in the contemporary age. | Dayong Qin Chuiyu Lu Jiahong Liu Hao Wang Jianhua Wang Haihong Li Junyin Chu Genfa Chen | 2014 | Chinese Science Bulletin2014，59，8： | 5 |
| 2 | Emodin promotes the osteogenesis of MC3T3- E1 cells via BMP-9/Smad pathway and exerts a preventive effect in ovariectomized rats显示文摘 | Xiaojing Chen Shuang Zhang Xiaoting Chen Yan Hu Jin Wu Shuyan Chen Jing Chang Genfa Wang Yanhong Gao | 2017 | Acta Biochimica et Biophysica Sinica2017，49，10： | 3 |
| 3 | Systematic review of atorvastatin for the treatment of Alzheimer's disease显示文摘OBJECTIVE:To assess the clinical efficacy and safety of atorvastatin in the treatment of Alz-heimer's disease.DATA SOURCES:Medline(1948/2011-04),Embase(1966/2011-04),Cochrane Library(Issue 3,2011),Chinese National Knowledge Infrastructure(1989/2011-04),and the Chinese Biomedical Literature Database(1979/2011-04) were searched for randomized clinical trials regardless of lan-guage.Abstracts of conference papers were manually searched.Furthermore,Current Controlled Trials(http://gffzz872f90091fd340c7hwf5v0ckwc55066uf.ffgz.tsg.suse.edu.cn),Clinical Trials.gov(http://gffzzd3f38a9638994581hwf5v0ckwc55066uf.ffgz.tsg.suse.edu.cn),and Chinese Clinical Trial Registry(http://gffzz9a58629d6cad4064hwf5v0ckwc55066uf.ffgz.tsg.suse.edu.cn) were also searched.Key words included Alzheimer disease,dementia,cognition,affection,memory dysfunction,hydroxymethylglutaryl-CoA reductase inhibitors,atorvastatin and statins.DATA SELECTION:Randomized controlled trials of grade A or B according to quality evaluation criteria of the Cochrane Collaboration were selected,in which atorvastatin and placebo were used to evaluate the effects of atorvastatin in the treatment of Alzheimer's disease.Study methodological quality was evaluated based on criteria described in Cochrane Reviewer's Handbook 5.0.1.Revman 5.1 software was used for data analysis.MAIN OUTCOME MEASURES:Clinical efficacy,safety,withdrawal from the studies,and withdrawal due to adverse effects.RESULTS:Two randomized controlled trials were included,one was scale A,and the other was scale B.All patients(n = 710,age range 50-90 years) were diagnosed as probable or possible mild to moderate Alzheimer's disease according to standard criteria and treated with atorvastatin 80 mg/d or placebo.There was no difference between the two groups in the final follow-up for Clinical Global Impression of Change scale(WMD = 0.13,95%CI:-0.15 to 0.40),the Alzheimer's Disease Assessment Scale-cognitive subscale(WMD = 1.05,95%CI:-3.06 to 6.05),Mini-Mental State Examination Scale(WMD = 0.77,95%CI:-0.57 to 2.10),and the Neuropsychiatric Instrument(WMD = 2.07,95%CI:-1.59 to 5.73).The rates of abnormal liver function,withdrawal from treatment,and withdrawal due to adverse effects were higher in the treatment group(OR = 7.86,95%CI:2.50-24.69;OR = 4.70,95%CI:2.61-8.44;and OR = 5.47,95%CI:3.01-9.94;respectively) com-pared with the placebo group.CONCLUSION:There is insufficient evidence to recommend atorvastatin for the treatment of mild to moderate Alzheimer's disease,because there was no benefit on general function,cognitive function or mental/behavior abnormality outcome measures.Efficacy and safety need to be confirmed by larger and higher quality randomized controlled trials,especially for moderate to severe Alzheimer's disease,because results of this systematic review may be limited by selection bias,implementation bias,as well as measurement bias. | Yuan Sun Genfa Wang Zhihong Pan Shuyan Chen | 2012 | Neural Regeneration Research2012，7，17： | 2 |
| 4 | A catastrophe model for water bloom prediction: a case study of China' s Lake Chaohu 显示文摘 | Chen Yunfeng Yin Fucai Lu Genfa | 2007 | Human and Ecological Risk Assessment2007，13，4： | 1 |
| 5 | Another strategy to assess sustainable development显示文摘The goal of sustainable development is to preserve sustainability and simultaneously prevent catastrophe in a man-land system. However, almost all the existing approaches to assessing sustainable development are to measure the sustainability, namely appraise from the obverse side of the sustainable development. So it seems necessary to attack the same task on the reverse, namely to measure the possibility of catastrophe. In this paper, with a case study of Tianjin, China, we employ catastrophe theory and models to integrate Tianjin’s sustainable development indicators, and then deduce the catastrophe risk index (CRI) to present the level of catastrophic possibility in the city. Applying catastrophe theory is a new strategy to assess sustainable development and shows great practical significance, especially for those developing regions or countries, who always give more priority to their economy and therefore have more obligation to make sure whether their social economic activities might bring forth any ecological environment catastrophe. Besides, being both qualitative and quantitative, the approach could be employed to explore not only static characteristics but also dynamic mechanism of man-land system. Although our work is only a maiden attempt and still calls for further effort to improve it, the case study of Tianjin in this paper would assure us the great promising future to apply catastrophe theory to sustainable development modeling. | Chen Yunfeng Lu Genfa | 2006 | Ecological Economy2006，2，2： | 1 |
| 6 | Research on regional capability constructive models of clean development mechanism显示文摘Global climate change has been identified as the first of the top ten environmental problems in the world. As climate change will have serious effects on the social and economic development and everyday living of people in the world, many of the countries and governments are taking untiring efforts to combat climate change. As one of the important mechanisms of reducing greenhouse gas (GHG) emissions in the Kyoto Protocol, Clean Development Mechanism (CDM) has not only provided chance for developed countries to fulf ill greenhouse emission reduction obligations, but also provided an opportunity for developing countries to combat climate change under the sustainable development frame. The dual objectives of developed countries' GHG emissions' reduction obligation achievement and developing countries' sustainable development will be achieved under the CDM. As a country with responsibility, China has been positively developing CDM projects and promoting energy saving and emissions reduction during the three years after the Kyoto Protocol came into force, and CDM projects development has always been in the front tank in the world. However, as the vast clime within China, notable differences occur in different regions. In order to promote the CDM development in China, it is necessary to have regional CDM capability construction in accordance with the practicality in different regions. Based on the Slat Analysis of developed CDM projects and current CDM development status in China, problems in the CDM development of China, including the inefficiency in small and medium-sized CDM Projects development, over centralization of CDM development scope and especially the differentiated provincial CDM projects developing capability are pointed out in the paper. What's more, reasons for the problems are analyzed from the leading factors, including policy orient, information asymmetry and weak CDM capability. In order to promote CDM projects development in China, a new CDM capability construction model is put forward in the paper. | Chen Leishan Liu Qingqiang Geng Jie Lu Genfa | 2009 | Ecological Economy2009，5，2： | 0 |
| 7 | Temporal Causal Relationship between Resource Use and Economic Growth in East China显示文摘现在的纸试图联合 cointegration 理论和材料流动分析途径在华东在江苏省检验在资源使用和真实 GDP 之间的原因的关系。学习从 1990 ~ 2007 考虑时期。我们为资源使用把直接材料输入用作代理变量。我们的评价显示真实 GDP 和资源使用是 cointegrated,仅仅从资源使用有单向性的长期间 Granger 诱发性跑到真实 GDP,然而并非反过来也如此。评价结果意味着资源以经济生长是一个限制因素,并且,因此,策略应该在华东为更精力旺盛的经济开发和一致资源使用被采用。而且,涉及礼品的新奇想法和方法论学习能乐意地被扩大为在资源使用和经济生长之间的关系的分析盖住另外的区域。 | Yuan Wang Jie Chen Genfa Lu | 2011 | China & World Economy2011，19，2： | 0 |
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