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6篇 您的检索式:作者名="Genís"
    题名 作者 年代 出处 被引量
1Matrix metalloproteinases:new routes to the use of MT1-MMP as a therapeutic target in angiogenesis-related disease显示文摘Arroyo AG Genís L Gonzalo P 2007Curr Pharm Des2007,13,17:1
2Geotechnical particle finite element method for modeling of soilstructure interaction under large deformation conditions显示文摘The possibilities of the particle finite element method(PFEM)for modeling geotechnical problems are increasingly evident.PFEM is a numerical approach to solve large displacement and large strain continuum problems that are beyond the capabilities of classical finite element method(FEM).In PFEM,the computational domain is reconfigured for optimal solution by frequent remeshing and boundary updating.PFEM inherits many concepts,such as a Lagrangian description of continuum,from classic geomechanical FEM.This familiarity with more popular numerical methods facilitates learning and application.This work focuses on G-PFEM,a code specifically developed for the use of PFEM in geotechnical problems.The article has two purposes.The first is to give the reader an overview of the capabilities and main features of the current version of the G-PFEM and the second is to illustrate some of the newer developments of the code.G-PFEM can solve coupled hydro-mechanical static and dynamic problems involving the interaction of solid and/or deformable bodies.Realistic constitutive models for geomaterials are available,including features,such as structure and destructuration,which result in brittle response.The solutions are robust,solidly underpinned by numerical technology including mixedfield formulations,robust and mesh-independent integration of elastoplastic constitutive models and a rigorous and flexible treatment of contact interactions.The novel features presented in this work include the contact domain technique,a natural way to capture contact interactions and impose contact constraints between different continuum bodies,as well as a new simplified formulation for dynamic impact problems.The code performance is showcased by the simulation of several soil-structure interaction problems selected to highlight the novel code features:a rigid footing insertion in soft rock,pipeline insertion and subsequent lateral displacement on over-consolidated clay,screw-pile pull-out and the dynamic impact of a free-falling spherical penetrometer into clay.Josep Maria Carbonell Lluís Monforte Matteo O.Ciantia Marcos Arroyo Antonio Gens 2022Journal of Rock Mechanics and Geotechnical Engineering2022,14,3:0
3Iron-Related Damage in Acute Ischemic Stroke显示文摘Antonio Dávalos José Manuel Fernandez-Real Wifredo Ricart Silvia Soler Albert Molins Elisa Planas David Genís 1994Stroke1994,,8:1
4Optical quality after myopic photorefractive keratectomy and laser in situ keratomileusis: Comparison using a double-pass system显示文摘Juan C. Ondategui Meritxell Vilaseca Montserrat Arjona Ana Montasell Genís Cardona José L. Güell Jaume Pujol 2012Journal of Cataract & Refractive Surgery2012,,1:1
5Allogeneic adipose stem cell therapy in acute myocardial infarction显示文摘Montserrat Rigol Núria Solanes Santiago Roura Mercè Roqué Laura Novensà Ana Paula Dantas Jaume Martorell Marta Sitges José Ramírez Antoni Bayés‐Genís Magda Heras 2014Eur J Clin Invest2014,,1:1
6Wnt genes in colonic polyposis predisposition显示文摘Much of the genetic predisposition to polyposis,and particularly to serrated polyposis(SP),remains unknown.Only germline pathogenic variants in RNF43,a tumor suppressor that exerts negative feedback in the Wnt/β-catenin signaling pathway,have been causally linked to some SP cases(<2%),a disease associated with increased risk of colorectal cancer(CRC).^(1) Most known hereditary CRC and polyposis genes affect DNA repair,BMP/TGF-β,or Wnt signaling,being the latter associated with adenomatous and serrated polyposis phenotypes.2 Based on this observation,we evaluated the presence and role of germline variants in those pathways in unsolved polyposis patients.Isabel Quintana Mariona Terradas Pilar Mur Iris B.A.Wte Paske Sophia Peters Isabel Spier Verena Steinke-Lange Claudia Maestro David Torrents Montserrat Puiggròs Romina Royo Raul Tonda Genís Parra Davide Piscia Sergi Beltrán Matilde Navarro Virginia Piñol Joan Brunet Noemi Gonzalez-Abuin Gemma Aiza Anna Sommer Yasmijn van Herwaarden Galuh Astuti Elke Holinski-Feder Nicoline Hoogerbrugge Richarda Mde Voer Stefan Aretz Gabriel Capellá Laura Valle 2023Genes & Diseases2023,10,3:0
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