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| 1 | Benzoxazole benzenesulfonamides are novel allosteric inhibitors of fructose1, 6-bisplaosphatase with a distinct binding mode 显示文摘 | yon Geldern TW Lai CQ Gum RJ | 2006 | Bioorg Med Chem Let-t2006，16，： | 1 |
| 2 | Discovery of((4R,5S) -5-amino-4- (2,4,5-trifluorophenyl) cyclohex-1-enyl) - (3- (trifluoromethyl) -5,6-dihydro- triazolo pyrazin-7 (8//) -yl methanone (ABT-341), a highly potent,selective, orally efficacious, and safe dipeptidyl peptidaseIV inhibitor for the treatment of type 2 diabetes 显示文摘 | Pei Z Von Geldern TW Madar DJ | 2006 | J MedChem2006，49，22： | 1 |
| 3 | Hepatic glucocorticoid receptor antagonism is sufficient to reduce elevated hepmic glucose output and improve glucose control in animal models of type 2 diabetes显示文摘 | Jacobson PB Geldern TW Ohman L | 2005 | J Pharrnacol Exp2005，，314： | 1 |
| 4 | Discovery and structureactivity relationships of piperidinone-and piperidine-constrained phenethylamines as novel,potent,and selective dipeptidyl peptidase IV inhibitors显示文摘 | Pei Z Li X Geldern TW | 2007 | Journal of Medicinal Chemistry2007，50，8： | 1 |
| 5 | Hepatic glucocorticoid receptor antagonism is sufficient to reduce elevated hepatic glucose output and improve glucose control in animal models of type 2 diabetes显示文摘 | Jacobson PB von Geldern TW (O)hman L | 2005 | J Pharmacol Exp Ther2005，314，： | 1 |
| 6 | Hepatic glucocorticoid receptor antagonism is sufficient to reduce elevated hepatic glucose output and improve glucose control in animal models of type 2 diabetes显示文摘 | Jacobson PB von Geldern TW Ohman L | 2005 | J Pharmacol Exp Ther2005，314，1： | 1 |
| 7 | Liver-selective glucocorticoid antagonists:a novel treatment for type 2 diabetes显示文摘 | von Geldern TW Tu N Kym PR | 2004 | J Med Chem2004，47，17： | 1 |
| 8 | Discovery of ((4R,5S)-5- amino-4-(2,4,5- trifluorophenyl)cyclohex-l-enyl)-(3- (trifluoromethyl)- 5,6-dihydro- triazolopyrazin-7(SH)-yl)methanone (ABT- 341), a highly potent, selective, orally efficacious, and safe dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes显示文摘 | Pei Z Li X von Geldern TW | 2006 | J Med Chem2006，49，22： | 1 |
| 9 | Discovery and structure activity relationships of piperidinone- and piperidine-constrained phenethylamines as novel, potent, and selective dipeptidyl peptidase Ⅳ inhibitors显示文摘 | PEI ZH LI XF GELDERN TW | 2007 | J Med Chem2007，50，8： | 1 |
| 10 | Discovery of ((4R,sS)-5-amino-4-(2,4,5- trifluorophenyl)cyclohex- 1 -enyl) -(3-(trifluoromethyl)-5,6-dihydro- triazolo pyrazin-7(SH)-yl)methanone (ABT-341), a highly potent, selective, orallyefficacious, and safe dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes显示文摘 | Pei Z Li X yon Geldern TW | 2006 | J Med Chem2006，49，22： | 1 |
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