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185篇 您的检索式:作者名="Gedde M M"
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1Hematopoietic cell transplantation for Crohn’s disease;is it time?显示文摘AIM: To review all studies in the literature that have assessed Hematopoietic cell transplantation (HCT) and Crohn’s disease (CD) with the ultimate aims of determining if this is a viable treatment option for those with CD. A secondary aim was to review the above literature and determine if the studies shed further light on the mechanisms involved in the pathogenesis of CD. METHODS: An extensive Medline search was performed on all articles from 1970 to 2005 using the ; bone marrow transplant, stem cell, hematopoietic cell, Crohn’s disease and inflammatory bowel disease. RESULTS: We identified one case in which a patient developed CD following an allogeneic HCT from a sibling suffering with CD. Evidence for transfer of the genetic predisposition to develop CD was also identified with report of a patient that developed severe CD following an allogeneic HCT. Following HCT it was found that the donor (that had no signs or symptoms of CD) and the recipient had several haplotype mismatches in HLA class Ⅲ genes in the IBD3 locus including a polymorphism of NOD2/CARD15 that has been associated with CD. Thirty three published cases of patients with CD who underwent either autologous or allogeneic HCT were identified. At the time of publication 29 of these 33 patients were considered to be in remission. The median follow-up time was seven years, and twenty months for allogeneic and autologous HCT respectively.For patients who underwent HCT primarily for treatment of their CD there have been no mortalities related to transplant complications. CONCLUSION: Overall these preliminary data suggest that both allogeneic and autologous HCT may be effective in inducing remission in refractory CD. Thissupports the hypothesis that the hematolymphatic cells play a key role in CD and that resetting of the immune system may be a critical approach in the management or cure of CD.Y Leung M Geddes J Storek R Panaccione PL Beck 2006World Journal of Gastroenterology2006,12,41:5
2Chest compression force of trained and untrained CPR rescuers显示文摘GEDDES L A BOLAND M K TALEYARKHAN P R 2007Cardiovasc Eng2007,7,:1
3Introduction: historical perspective and development of amoxicillin/clavulanate 显示文摘GEDDES A M KLUGMAN K P ROLINSON G N 2007lnt J Antimicrob Agent2007,30,2:1
4The vagcular basis of the thoracodorsal artery perforator flap显示文摘THOMAS B P GEDDES C R TANG M 2005Plast Reconstr Surg2005,116,3:1
5Bronchoscopic lung vol- ume reduction for end-stage emphysema: report on the first 98 patients显示文摘Wan I Y Toma T P Geddes D M 2006Chest2006,129,:1
6Vascular basis of intrinsic muscle flaps in the hand显示文摘TANG M THOMAS B P GEDDES C R 2008Hast Reconstr Surg2008,122,1:1
7Granular cell change in astrocytic tumors显示文摘Geddes J F Thom M Robinson S 1996Am J Surg Pathol1996,20,:1
8Microglial activation is a pharmacologically specific marker for the neurotoxic amphetamines显示文摘THOMAS D M DOWGIERT J GEDDES T J 2004Neurosci Lett2004,367,3:1
9Pole-zero cancellations and closed-loop properties of an H∞ mixed sensitivity design problem 显示文摘Tsai M C Geddes E J M Postlethwaite I 1992Automatica1992,28,3:1
10Effect of exogenous and endogenous antioxidants on 3-nitropionic acid-induced in vivo oxidative stress and striatal lesions: insights into Huntington' s disease显示文摘LA FONTAINE M A GEDDES J W BAANKS A 2000J Neurochem2000,75,:1
11Treatment of older patients with acute myeloid leukemia(AML):a Canadian consensus显示文摘Brandwein JM Geddes M Kassis J 2013Am J Blood Res2013,3,:1
120steocalcin, skeletal alkaline phosphatase, and bone mineral content in very low birth weight infants : a longitudinal assessment显示文摘Pittard W B Geddes K M Hulsey T C 1992Pediatric Research1992,31,2:1
13Degradation of poly(ethylene-co-methyl methacrylic acid )-calcium carbonate nomocomposites 显示文摘Kramer P H Raza M A Gedde U W 2007Polymer Degradation and Stability2007,,92:1
14Corona destruction: An innovative control technology for VOCS and air toxies 显示文摘Carlos M Nunez Geddes H Ramsey Wade H Ponder 1993Air & Waste Management Association1993,,43:1
15Exploring the dimensions of emotional labor显示文摘 Geddes D 2000Management Communication Quarterly2000,14,1:1
16A compact high performance W-band FMCW radar front-end based on MMIC technology 显示文摘Lamberg J R Gawronski M J Geddes J J 1999Microwave Symposium Digest1999,,4:1
17Modified lead oxide-gelatin injection technique for vascular studies 显示文摘Tang M Geddes CR Yang D 2002J Clin Anat2002,1,1:1
18Permanent focal and transient global cerebral ischemia increase glial and neuronal expression of heine oxygenase-1, but not heine oxygenase-2, protein in rat brain显示文摘Geddes J W Pettigrew L C Hohz M L 1996Neurosci Lett1996,210,3:1
19Role of listeriolysin O in cell-to-cell spread of Listeria monocytogenes 显示文摘Gedde M M Higgins D E Tilney L G 2000Infect Immun2000,4,68:1
20Electron injection and emittance control by transverse colliding pulses in a laser-plasma accelerator显示文摘Chen M Esarey E Geddes C G 2014American Physical Society2014,17,5:1
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