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| 1 | 微小RNA-1和微小RNA-29b对急性心肌梗死后不良心室重塑的诊断和预后价值显示文摘已知微小RNA(microRNAs,miRs)在急性心肌梗死(acute myocardial infarction,AMI)临床前期模型中可发挥纤维化和抗纤维化作用。为了评估miR-1,miR-21,miR-29b和miR-92a能否作为患者发生AMI后不良心室重塑(adverse ventricular remodeling,AVR)的循环生物标志物, | 刘莉 叶鹏 Grabmaier U Clauss S Gross L Klier I Franz WM Steinbeck G Wakili R Theiss HD Brenner C | 2017 | 中华高血压杂志2017，25，7： | 17 |
| 2 | Characterization of a critical role for CFTR chloride channels in cardioprotection against ischemia/ reperfusion injury显示文摘目的: 进一步描绘膀胱的纤维变性 transmembrane 传导力管理者(CFTR ) 的功能的角色在早、迟了(第二扇窗户) ischemic preconditioning (欧洲电脑生产厂商)- 并且 postconditioning (停靠港) 调停了对 ischemia/reperfusion (I/R ) 的 cardioprotection 损害。 | Sunny Yang XIANG Linda L YE Li-lu Marie DUAN Li-hui LIU Zhi-dong GE John A AUCHAMPACH Garrett J GROSS Dayue Darrel DUAN | 2011 | Acta Pharmacologica Sinica2011，32，6： | 9 |
| 3 | A systematic review and meta-analysis of clinical trials implementing aromatase inhibitors to treat male infertility显示文摘Aromatase activity has commonly been associated with male infertility characterized by testicular dysfunction with low serum testosterone and/or testosterone to estradiol ratio.In this subset of patients,and particularly in those with hypogonadism,elevated levels of circulating estradiol may establish a negative feedback on the hypothalamic–pituitary–testicular axis by suppressing follicle-stimulating hormone(FSH)and luteinizing hormone(LH)production and impaired spermatogenesis.Hormonal manipulation via different agents such as selective estrogen modulators or aromatase inhibitors to increase endogenous testosterone production and improve spermatogenesis in the setting of infertility is an off-label option for treatment.We carried out a systematic review and meta-analysis of the literature of the past 30 years in order to evaluate the benefits of the use of aromatase inhibitors in the medical management of infertile/hypoandrogenic males.Overall,eight original articles were included and critically evaluated.Either steroidal(Testolactone)or nonsteroidal(Anastrozole and Letrozole)aromatase inhibitors were found to statistically improve all the evaluated hormonal and seminal outcomes with a safe tolerability profile.While the evidence is promising,future prospective randomized placebo-controlled multicenter trials are necessary to better define the efficacy of these medications. | Francesco Del Giudice Gian Maria Busetto Ettore De Berardinis Isabella Sperduti Matteo Ferro Martina Maggi Martin S Gross Alessandro Sciarra Michael L Eisenberg | 2020 | Asian Journal of Andrology2020，22，4： | 5 |
| 4 | Endocrine radionuclide scintigraphy with fusion single photon emission computed tomography/computed tomography显示文摘AIM: To review the benefits of single photon emission computed tomography(SPECT)/computed tomography(CT) hybrid imaging for diagnosis of various endocrine disorders.METHODS: We performed MEDLINE and Pub Med searches using the terms: 'SPECT/CT'; 'functional anatomic mapping'; 'transmission emission tomography'; 'parathyroid adenoma'; 'thyroid cancer'; 'neuroendocrine tumor'; 'adrenal'; 'pheochromocytoma'; 'paraganglioma'; in order to identify relevant articles published in English during the years 2003 to 2015. Reference lists from the articles were reviewed to identify additional pertinent articles. Retrieved manuscripts(case reports, reviews, meta-analyses and abstracts) concerning the application of SPECT/CT to endocrine imaging were analyzed to provide a descriptive synthesis of the utility of this technology.RESULTS: The emergence of hybrid SPECT/CT camera technology now allows simultaneous acquisition of combined multi-modality imaging, with seamless fusion of three-dimensional volume datasets. The usefulness of combining functional information to depict the biodistribution of radiotracers that map cellular processes of the endocrine system and tumors of endocrine origin, with anatomy derived from CT, has improved the diagnostic capability of scintigraphy for a range of disorders of endocrine gland function. The literature describes benefits of SPECT/CT for ^(99m)Tc-sestamibi parathyroid scintigraphy and ^(99m)Tc-pertechnetate thyroid scintigraphy, ^(123)I- or ^(131)I-radioiodine for staging of differentiated thyroid carcinoma, ^(111)In- and ^(99m)Tclabeled somatostatin receptor analogues for detection of neuroendocrine tumors, ^(131)I-norcholesterol(NP-59) scans for assessment of adrenal cortical hyperfunction, and ^(123)I- or ^(131)I-metaiodobenzylguanidine imaging for evaluation of pheochromocytoma and paraganglioma.CONCLUSION: SPECT/CT exploits the synergism between the functional information from radiopharmaceutical imaging and anatomy from CT, translating to improved diagnostic accuracy and meaningful impact on patient care. | Ka-Kit Wong Arpit Gandhi Benjamin L Viglianti Lorraine M Fig Domenico Rubello Milton D Gross | 2016 | World Journal of Radiology2016，8，6： | 3 |
| 5 | Wegener肉芽肿病CD4^+CD28^-T细胞的免疫表型及功能的研究显示文摘目的 研究Wegener 肉芽肿病( Wegener′s granulomatosis,WG) 协同刺激分子(costimulatory molecules,CosM)CD28/CTLA4CD80/CD86 的表达以及CD4 + CD28 - T 细胞的免疫表型特征和功能。方法 CosM 的表达用FACS多参数分析测定。CD4 + CD28- T细胞与不同刺激剂共同培养后测定其增生反应的程度及细胞因子的分泌。结果 WG 外周血中CD4 + CD28 - T 细胞明显增多。它们表达CD25、CD38 、CD45RO、HLADR 以及CD86 显著增加,且对自身抗原蛋白酶3 的刺激呈明显增生反应。在抗原提呈细胞(antigen presenting cell,APC) 及抗CD3 共同作用下,CD4+CD28- T 细胞的增生活跃,但这种增生反应不能被CTLA4 Ig、抗CD80 及抗CD86 所抑制。CD4+CD28- T细胞分泌IFNγ的量明显高于CD4 + CD28 - T 细胞。另外,CD4 + CD28 - T 细胞还能诱导正常CD4 + T 细胞的活化和增生。结论 WGCD4 + CD28- T 细胞明显增多,它们可能是一类已被活化的自身? | 王国春 王晓娣 Csernok E Gross W L | 1999 | 中华风湿病学杂志1999，3，4： | 3 |
| 6 | I, 25-Dihydroxyvitarnin D3 decreases podocyte loss and podocyte hypertrophy in the subtotaUy nephrectomized rat 显示文摘 | Kuhimann A Haas S Gross L | 2004 | Am J Physiol Renal Physiol2004，286，3： | 1 |
| 7 | The antiangiogenic agent linomide inhibits the growth rate of von Hippel-Lindau paraganglioma xenografts to mice 显示文摘 | Gross D J Reibstein I Weiss L | 1999 | Clin Cancer Res1999，5，11： | 1 |
| 8 | Location Choice of Foreign Banks in the United States显示文摘 | Goldberg L G Grosse R | 1994 | Journal of Economics and Business1994，46，： | 1 |
| 9 | Ionic-liquid matrices for improved analysis of phospholipids by MALDI-TOF mass spectrometry显示文摘 | LI Y L GROSS M L HSU F | 2005 | Journal of the American Society for Mass Spectrometry2005，16，5： | 1 |
| 10 | Enzyme-catalyzed ring-opening polymerization of ω-pentadecalactone显示文摘 | Bisht K S Henderson L A Gross R A | | 0，，08： | 1 |
| 11 | Pseudomonas syringae phytotoxins:mode of action,regulation,and biosynthesis by peptide and polyketide synthetases显示文摘 | Bender C L Alarcon-Chaidez F Gross D C | | 0，，： | 1 |
| 12 | Time -frequency a- nalysis of the endocavitarian signal in paroxysmal atrial fi- brillation显示文摘 | Pagana G Galleani L Gross S | 2012 | IEEE T Bio Med Eng2012，59，10： | 1 |
| 13 | Enhanced hydrogen storage kinetics of LiBH4 in nanoporous carbon scaffolds显示文摘 | Gross A F Vajo J J Van Atta S L | 2008 | The Journal of Physical Chemistry C2008，112，14： | 1 |
| 14 | Transfer of the gene for neomycin resistance into goldfish (Carassius auratus)显示文摘 | Hallerman E M Gross M L | 1990 | Aquaculture1990，85，： | 1 |
| 15 | Develop- mental abnormalities of the gonad and abnormal sex hor- mone concentrations in juvenile alligators from contaminated and control lakes in Florida 显示文摘 | Guillette L J Gross Jr T S Masson G R | 1994 | Environmental Health Per- spectives1994，102，8： | 1 |
| 16 | Ion chromatog raphic determination of nitrate and nitrite in vegetable and fruit baby foods显示文摘 | MCMULLEN S E CASANOVA J A GROSS L K | 2005 | J AOAC Int2005，88，6： | 1 |
| 17 | Why we buy what we buy: A theory of consumption values 显示文摘 | Sheth J N Newman B I Gross B L | 1991 | Journal of business research1991，22，2： | 1 |
| 18 | Primary pulmonary paraganglioma:case report andliterature review显示文摘 | da Silva R A Gross J L Haddad F J | | 0，，： | 1 |
| 19 | Fast atom bombardment and tandem mass spectrometry of phosphatidylserine and phosphatidylcholine 显示文摘 | JENSEN N J TOMER K B GROSS M L | 1986 | Lipids1986，21，9： | 1 |
| 20 | The cell surface- localized heat shock protein 70 epitope TKD induces migration and cytolytic activity selectively in human NK cells显示文摘 | Gastpar R Gross C Rossbacher L | 2004 | J Immunol2004，172，97： | 1 |
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