|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Wegener肉芽肿病CD4^+CD28^-T细胞的免疫表型及功能的研究显示文摘目的 研究Wegener 肉芽肿病( Wegener′s granulomatosis,WG) 协同刺激分子(costimulatory molecules,CosM)CD28/CTLA4CD80/CD86 的表达以及CD4 + CD28 - T 细胞的免疫表型特征和功能。方法 CosM 的表达用FACS多参数分析测定。CD4 + CD28- T细胞与不同刺激剂共同培养后测定其增生反应的程度及细胞因子的分泌。结果 WG 外周血中CD4 + CD28 - T 细胞明显增多。它们表达CD25、CD38 、CD45RO、HLADR 以及CD86 显著增加,且对自身抗原蛋白酶3 的刺激呈明显增生反应。在抗原提呈细胞(antigen presenting cell,APC) 及抗CD3 共同作用下,CD4+CD28- T 细胞的增生活跃,但这种增生反应不能被CTLA4 Ig、抗CD80 及抗CD86 所抑制。CD4+CD28- T细胞分泌IFNγ的量明显高于CD4 + CD28 - T 细胞。另外,CD4 + CD28 - T 细胞还能诱导正常CD4 + T 细胞的活化和增生。结论 WGCD4 + CD28- T 细胞明显增多,它们可能是一类已被活化的自身? | 王国春 王晓娣 Csernok E Gross W L | 1999 | 中华风湿病学杂志1999，3，4： | 3 |
| 2 | Identification,culture,and characterization of pancreatic stellate cells in rats and humans显示文摘 | Bachem MG Schneider E Gross H | | Gastroenterology0，，： | 2 |
| 3 | Hyperglycemia-induced beta-cell,apoptosis in pancreatic islets of psammomys obesus during development of diabetes显示文摘 | Donath MY Gross DJ Cerasi E | 1999 | Diabetes1999，48，4： | 1 |
| 4 | Allelopathy of aquatic autotrophs 显示文摘 | Gross E M | 2003 | Critical Reviews in Plant Sciences2003，22，34： | 1 |
| 5 | Australian rangelands as complex adaptive systems: A conceptual model and pre- liminary results显示文摘 | Gross J E McAllister R R J Abel N | 2005 | Environmental Modeling & Software2005，9，21： | 1 |
| 6 | Key role of Teichoic acid net charge in staphylococcus aureus colonization of artificial Surface显示文摘 | GROSS M CRAMTON S E GOTZ F | 2001 | Infect Immun2001，65，： | 1 |
| 7 | Ischemic preconditioning in the intact rat heart is mediated by deltal but not mu-or kappa-opioid receptors显示文摘 | Schultz J E Hsu A K Gross G J | 1998 | Circulation1998，97，13： | 1 |
| 8 | Neurogenesis in the adult mammals:some progress and problems显示文摘 | Gould E Gross CG | 2002 | J Neurosci2002，22，3： | 1 |
| 9 | Netlib and NA-Net: Building a scientific computing community 显示文摘 | DONGARRA J GOLUB G GROSSE E | 2008 | IEEE Annals of the history of computing2008，30，2： | 1 |
| 10 | An fMRI Study of Personality Influences on Brain Reactivity to Emotional Stimuli显示文摘 | Canli T Zhao Z Desmond E J Kang E Gross J Gabrieli J D E | | 0，，01： | 1 |
| 11 | 查看详情显示文摘 | D W Yoon D E Gross V M Lynch J M Sessler B P Hay C H Lee | | 0，，： | 1 |
| 12 | Can allelopathically active submerged macrophytes stabilize clear-water states in shallow lakes?显示文摘 | HILT S GROSS E M | 2008 | Basic Appl Ecol2008，9，： | 1 |
| 13 | Zur morphologie der Bromeliaceen samen unter berucksichtig-ung systematisch-taxonomischer aspekte显示文摘 | Gross E Bromelienstudien I V | 1988 | Tropische und subtropische Pflanzenwelt1988，64，： | 1 |
| 14 | Transfer of the gene for neomycin resistance into goldfish (Carassius auratus)显示文摘 | Hallerman E M Gross M L | 1990 | Aquaculture1990，85，： | 1 |
| 15 | Discovery of synthetic penaeidin activity against antibiotic-resistant fungi显示文摘 | Cuthbertson B J Bullesbach E E Gross P S | 2006 | Chemical Biology&Drug Design2006，68，2： | 1 |
| 16 | A highly sensitive,fast and economical technique for mutation analysis in hereditary breast and ovarian cancers显示文摘 | Arnold N Gross E Schwarz-Boeger U | 1999 | Hum Mutat1999，14，： | 1 |
| 17 | Neurogenesis in the Neocortex of Adult Primates显示文摘 | Gould E Reeves AJ Graziano MSA Gross CG | 1999 | Science1999，，286： | 1 |
| 18 | Laparoscopic compared with conven-tional treatment of acute adhesive small bowel obstruction显示文摘 | Wullstein C Gross E | 2003 | Br J Stag2003，90，9： | 1 |
| 19 | Ion chromatog raphic determination of nitrate and nitrite in vegetable and fruit baby foods显示文摘 | MCMULLEN S E CASANOVA J A GROSS L K | 2005 | J AOAC Int2005，88，6： | 1 |
| 20 | Opioid-induced cardioprotection occurs via glycogen synthase kinase beta inhibition during reperfusion in intact rat hearts 显示文摘 | GROSS E R HSU A K GROSS G J | 2004 | Circ Res2004，94，7： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员