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41篇 您的检索式：作者名="GOULART P"

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	题名	作者	年代	出处	被引量
1	Use of butyrate or glutamine in enema solution reduces inflammation and fibrosis in experimental diversion colitis显示文摘AIM:To investigate whether butyrate or glutamine enemas could diminish inflammation in experimental diversion colitis.METHODS:Wistar specific pathogen-free rats were submitted to a Hartmann's end colostomy and treated with enemas containing glutamine,butyrate,or saline.Enemas were administered twice a week in the excluded segment of the colon from 4 to 12 wk after the surgical procedure.Follow-up colonoscopy was performed every 4 wk for 12 wk.The effect of treatment was evaluated using video-endoscopic and histologic scores and measuring interleukin-1β,tumor necrosis factor-alpha,and transforming growth factor beta production in organ cultures by enzyme linked immunosorbent assay.RESULTS:Colonoscopies of the diverted segment showed mucosa with hyperemia,increased number of vessels,bleeding and mucus discharge.Treatment with either glutamine or butyrate induced significant reductions in both colonoscopic(P < 0.02) and histological scores(P < 0.01) and restored the densities of collagen fibers in tissue(P = 0.015;P = 0.001),the number of goblet cells(P = 0.021;P = 0.029),and the rate of apoptosis within the epithelium(P = 0.043;P = 0.011) to normal values.The high levels of cytokines in colon explants from rats with diversion colitis significantly decreased to normal values after treatment with butyrate or glutamine.CONCLUSION:The improvement of experimental diversion colitis following glutamine or butyrate enemas highlights the importance of specific luminal nutrients in the homeostasis of the colonic mucosa and supports their utilization for the treatment of human diversion colitis.	Rodrigo Goulart Pacheco Christiano Costa Esposito Lucas CM Müller Morgana TL Castelo-Branco Leonardo Pereira Quintella Vera Lucia A Chagas Heitor Siffert P de Souza Alberto Schanaider	2012	World Journal of Gastroenterology2012，18，32：	9
2	Transmissao de Pyricularia oryzae atraves de semetes de trigo ( Triticum aestivum) 显示文摘	Goulart A C P Paiva F A	1990	Fitopatologia Brassileira1990，15，4：	1
3	Opti- mization over state feedback policies for robust control with con- straints 显示文摘	GOULART P J KERRIGAN E C MACIEJOWSK/ J M	2006	Automatica2006，42，4：	1
4	An inhibitory Ig su-perfamily protein expressed by lymphocytes and APCs is also an early marker of thymocyte positive selection显示文摘	Han P Goularte OD Rufner K	2004	J Immu-nol2004，172，：	1
5	Mathematical Programming Models and Algorithms for Engineering Design Optimization 显示文摘	Herskovits J Mappa P Goulart E	2005	Computer Methods in Applied Mechanics and Engineering (S0045-7825)2005，194，3033：	1
6	Mathematical programming models and algorithms for engineering design optimization显示文摘	Herskovits J Mappa P Goulart E	2005	Computer Methods in Applied Mechanics Engineering2005，194，3033：	1
7	An inhibitory Ig superfamily protein expressed by lymphocytes and APCs is also an early marker of thymoeyte positive selection 显示文摘	Han P Goularte O D Rufner K Wilkinson B Kaye J	2004	J Immunol2004，172，：	1
8	An inhibitory Ig superfamily protein expressed by lymphocytes and APCs is also an early marker of thymocyte positive selection显示文摘	Han P Goularte O D Rufner K	2004	J Immunol2004，172，10：	1
9	An inhibitory Ig superfamily protein expressed by lymphocytes and APCs is an early marker of thymocyte positive selection 显示文摘	Han P Goularte OD Rufner K etal	2004	J Immunol2004，172，：	1
10	An inhibitory Ig superfamily protein expressed by lymphocytes and APCs is also an earty marker of thymocyte positive selection显示文摘	Han P Goularte OD Rufner K	2004	J Immunol2004，173，5：	1
11	An inhibitory Ig superfamily protein expressed by lymphocytes and APCs is also an early marker of thymocyte positive selection显示文摘	Han P Goularte OD Rufner K	2004	J Immunol2004，172，10：	1
12	Effect of dendritic arm spacing on mechanical properties and corrosion resistance of Al-9 wt pct Si and Zn-27 wt pet Al alloys 显示文摘	OSARIO W R GOULART P R SANTOS G A NETCO C M GARCIA A	2006	Metallurgical and Materials Transactions A2006，37，：	1
13	Effect of silicon content on microstructure and electrochemical behavior of hypoeutectic Al-Si alloys 显示文摘	OSORIO W R GOULART P R GARCIA A	2008	Materials Letters2008，62，：	1
14	Mathematical programming model and algorithms for engineering design optimization显示文摘	HERSKOVITS J MAPPA P GOULART E	2005	Computer Methods in Applied Mechanics and Engineering2005，194，：	1
15	Mathematical programming model and algorithms for engineering design optimization显示文摘	HERSKOV1TS J MAPPA P GOULART E	2005	Computer Methods in Applied Mechanics and Engineering2005，194，33：	1
16	Effect of silicon content on microstructure and electrochemical behavior of hypoeutectic Al-Si alloys显示文摘	OSORIO W R GOULART P R GARCIA A	2008	Materials Letters2008，62，3：	1
17	An inhibitory Ig superfamily protein expressed by lymphocytes and APC is an early marker of thymocyte positive selection显示文摘	Han P Goularte OD Rufner K	2004	J Immunol2004，172，：	1
18	Wheat yield losses due to Pyricularia oryzae in 1988-91 period in Mato Grosso do Sul显示文摘	Goulart A C P Paiva F de A	1992	Fitopatologia Brasileira1992，17，：	1
19	An inhibitory Ig superfamily protein expressed by lymphocytes and APCs is an early marker of thymocyte positive selection显示文摘	Han P Goularte OD Rufner K	2004	Jimunol2004，172，10：	1
20	Molybdenum applied to seeds and side dressing nitrogen on irrigated common bean in cerrado soil 显示文摘	Biscaro G A Goulart Junior S A R Soratto R P	2009	Cienc Agrotec2009，33，5：	1

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