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| 1 | Overexpression of glyoxalase-1 in bovine endothelial cells inhibits intracellular advanced glycation endproduct formation and prevents hyperglycemia-induced increases in macromolecular endocytosis显示文摘 | Shinohara M Thomalley PG Giardino I | 1998 | J Clin Invest1998，101，5： | 1 |
| 2 | Detecting chlorophyll, Secchi disk depth and surface temperature in a sub-alp in-lake using Landsat imagery显示文摘 | GIARDINO C | 2001 | The Science of the Total Environment2001，268，13： | 1 |
| 3 | Urea determination in milk by a differential pH technique显示文摘 | LUZZANA M GIARDINO R | 1999 | Le Lait1999，79，： | 1 |
| 4 | Antiplatelet and an-tithrombotic activity of RWJ-53308,a novel orally active glycoprotenⅡb/ Ⅲa antagonist显示文摘 | Damiano BP Mitchell JA Giardino E | 2005 | Thromb Res2005，104，2： | 1 |
| 5 | Epithelialmesenchymal transition of tubular epithelial cells in human renal biopsies显示文摘 | Rastaldi MP Ferrario F Giardino L | 2002 | Kidney Int2002，62，1： | 1 |
| 6 | Enhanced guided bone regeneration with a resorbable chamber containing demineralized bone matrix显示文摘 | Giardino R Aldini NN Fini M | 2002 | J Trauma2002，52，5： | 1 |
| 7 | Exer- cise ventilatory inefficiency and mortality in patients with chronic obstructive pulmonary disease undergoing surgery for non-small-cell lung cancer 显示文摘 | TORCHIO R GUGLIELMO M GIARDINO R | 2010 | Eur J Cardiothorac Surg2010，38，1： | 1 |
| 8 | MRI and CT in the evaluation of congenital heart diseases 显示文摘 | Secchi F Giardino A Nardella VG | 2010 | Pediatr Med Chit2010，32，6： | 1 |
| 9 | Nerve growth factor control of neuronal expression of angiogenetic and vasoactive factors显示文摘 | Calza L Giardino L Giuliani A | 2001 | Proc Natl Acad Sci USA2001，98，7： | 1 |
| 10 | Balance between NF-κB p100 and p52 regulates T cell costimulation dependence显示文摘 | Giardino Torchia ML Conze DB Jankovic D | | 0，，02： | 1 |
| 11 | Costs of pulmonary rehabilitation and predictors of adherence in the National Emphysema Treatment Trial 显示文摘 | Fan V S Giardino N D Blough D K | 2008 | COPD2008，5，2： | 1 |
| 12 | Autologous bone marrow stromal cells loaded onto porous hydroxyapatite ceramic accelerate bone repair in critical-size defects of sheep long bones显示文摘 | Kon E Muraglia A Corsi A Bianco P Marcacci M Martin I Boyde A Ruspantini I Chistolini P Rocca M Giardino R Cancedda R Quarto R | | 0，，： | 1 |
| 13 | Histomorphometric and mechanical analysis of the hydroxyapatite-bone interface after electromagnetic stimulation:an experimental study in rabbits显示文摘 | Fini M Giavaresi G Giardino R | 2006 | J Bone Joint Surg Br2006，88，1： | 1 |
| 14 | Neural stem cells isolated from amyloid precursor proteinmutated mice for drug discovery显示文摘AIM: To develop an in vitro model based on neural stem cells derived from transgenic animals, to be used in the study of pathological mechanisms of Alzheimer's disease and for testing new molecules.METHODS: Neural stem cells(NSCs) were isolated from the subventricular zone of Wild type(Wt) and Tg2576 mice. Primary and secondary neurosphere generation was studied, analysing population doubling and the cell yield per animal. Secondary neurospheres were dissociated and plated on MCM Gel Cultrex 2D and after 6 d in vitro(DIVs) in mitogen withdrawal conditions,spontaneous differentiation was studied using specific neural markers(MAP2 and TuJ-1 for neurons, GFAP forastroglial cells and CNPase for oligodendrocytes). Gene expression pathways were analysed in secondary neurospheres, using the QIAGEN PCR array for neurogenesis, comparing the Tg2576 derived cell expression with the Wt cells. Proteins encoded by the altered genes were clustered using STRING web software.RESULTS: As revealed by 6E10 positive staining, all Tg2576 derived cells retain the expression of the human transgenic Amyloid Precursor Protein. Tg2576 derived primary neurospheres show a decrease in population doubling. Morphological analysis of differentiated NSCs reveals a decrease in MAP2- and an increase in GFAP-positive cells in Tg2576 derived cells. Analysing the branching of TuJ-1 positive cells, a clear decrease in neurite number and length is observed in Tg2576 cells.The gene expression neurogenesis pathway revealed11 altered genes in Tg2576 NSCs compared to Wt.CONCLUSION: Tg2576 NSCs represent an appropriate AD in vitro model resembling some cellular alterations observed in vivo, both as stem and differentiated cells. | Vito Antonio Baldassarro Mercedez Fernández Giulia Lizzo Michela Paradisi Luciana Giardino Laura Calzà Giulia Lizzo | 2013 | World Journal of Stem Cells2013，5，4： | 1 |
| 15 | Non-random trisomies of chromosomes 5,8 and 12 in the prolactinoma sub-type of pituitary adenomas: conventional cytogenetics and interphase FISH study 显示文摘 | Finelli P Giardino D Rizzi N | 2000 | Int J Cancer2000，86，3： | 1 |
| 16 | Respiratory sinus arrhythmia is associated with efficiency of pulmonary gas exchange in healthy humans显示文摘 | GIARDINO N D GLENNY R W BORSON S | 2003 | Am J Physiol Heart Circ Physiol2003，284，5： | 1 |
| 17 | Prenatal diagnosis of a de no-vo complex chromosome rearrangement ( CCR) mediated by sixbreakpoints,and a review of 20 prenatally ascertained CCRs 显示文摘 | Giardino D Corti C Ballarati L | 2006 | Prenat Diagn2006，26，： | 1 |
| 18 | Intestinal Giardiasis Associated with Ophthalmologic Changes显示文摘 | M. Pettoello Mantovani I. Giardino A. Magli L. di Martino S. Guandalini | 1990 | Journal of Pediatric Gastroenterology and Nutrition1990，，2： | 1 |
| 19 | Dimensions of nursecaring显示文摘 | Wolf Z Giardino E Osborne P | 1994 | J Nurs Scholarsh1994，26，2： | 1 |
| 20 | Epithelial-mesenchymal transition of tubular epithelial cells in human renal biopsies显示文摘 | Rastaldi MP FelTario F Giardino L | 2002 | Kid- ney Int2002，62，1： | 1 |
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