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| 1 | 铂和HF掺杂的H-ZSM-5分子筛催化甲苯与甲醇烷基化反应(英文)显示文摘Toluene was alkylated with methanol in a flow type reactor at temperatures between 300 and 500 °C using H-ZSM-5 zeolite, 0.2%Pt/H-ZSM-5 and hydrofluorinated 0.2%Pt/H-ZSM-5 with HF concentrations of 1.0%, 2.0%, 3.0%, or 4.0%. Pt primarily enhances toluene conversion, total xylenes production, and p-xylene relative to its thermodynamic equilibrium. As the concentration of HF increases from 1.0% to 3.0%, the catalyst activity increases because of the increase in the number of acid sites and their strength. Additionally, the surface area and Pt dispersion also increases. An advantage of increased HF doping is that the formation of voluminous trimethylbenzene (TMB) byproducts is inhibited. However, at a HF concentration of 4.0%, Al and Si are partially leached and then deposited mostly in the wider catalytic pores. This was determined by evaluating the pore volume distribution and we determined that reactivity inhibition was ob-viously present and was due to diffusion restriction. | Ahmed K. ABOUL-GHEIT Ateyya A. ABOUL-ENEIN Ahmed E. AWADALLAH Salwa A. GHONEIM Eman A. EMAM | 2010 | 催化学报2010，31，10： | 4 |
| 2 | Serum complement C4a and its relation to liver fibrosis in children with chronic hepatitis C显示文摘AIM:To evaluate serum complement C4a and its relation to liver fibrosis in children with chronic hepatitis C virus(HCV)infection.METHODS:The study included 30 children with chronic HCV infection before receiving antiviral therapy.Chronic HCV infection was defined by positive anti-HCV,a positive polymerase chain reaction for HCV-RNA for more than 6 mo with absence of any associated liver disease.A second group of 30 age-and sex-matched healthy children served as controls.Serum C4a levels were measured by enzyme-linked immunosorbent assay.Liver fibrosis stage and inflammatory grade were assessed using Ishak scoring system.Serum C4a levels were compared according to different clinical,laboratory and histopathological parameters.Statistical significance for quantitative data was tested by MannWhitney U non-parametric tests.For qualitative data,significance between groups was tested by 2test.Correlation was tested by Spearman’s test.Results were considered significant if P value≤0.05.RESULTS:The age of the patients ranged from 3.5to 18 years and that of controls ranged from 4 to 17years.C4a mean levels were merely lower in patients(153.67±18.69 mg/L)than that in the controls(157.25±11.40 mg/L)with no statistical significance(P=0.378).It did not differ significantly in patients with elevated vs those with normal transaminases(152.25±16.62 vs 155.36±21.33;P=0.868)or with different HCV viremia(P=0.561).Furthermore,there was no statistical significant difference in serum levels between those with no/mild fibrosis and those with moderate fibrosis(154.65±20.59 vs 152.97±17.72;P=0.786)or minimal and mild activity(155.1±21.93 vs 152.99±17.43;P=0.809).Though statistically not significant,C4a was highest in fibrosis score 0(F0),decreasing in F1 and F2 to be the lowest in F3.When comparing significant fibrosis(Ishak score≥3)vs other stages,C4a was significantly lower in F3 compared to other fibrosis scores(143.55±2.33 mg/L vs 155.26±19.64 mg/L;P=0.047)and at a cutoff value of less than 144.01 mg/L,C4a could discriminate F3 with 76.9%sensitivity and75%specificity from other stages of fibrosis.CONCLUSION:Serum complement C4a did not correlate with any of transaminases,HCV viremia or with the histopathological scores.Although C4a decreased with higher stages of fibrosis,this change was not significant enough to predict individual stages of fibrosis.Yet,it could predict significant fibrosis with acceptable clinical performance. | Behairy E Behairy Ghada M El-Mashad Ragab S Abd-Elghany Enas M Ghoneim Mostafa M Sira | 2013 | World Journal of Hepatology2013，5，8： | 4 |
| 3 | The Incidence of Awareness During Anesthesia: A Multicenter United States Study显示文摘 | Peter S. Sebel T. Andrew Bowdle Mohamed M. Ghoneim Ira J. Rampil Roger E. Padilla Tong Joo Gan Karen B. Domino | 2004 | Anesthesia & Analgesia2004，，3： | 3 |
| 4 | Gastrointestinal and hepatic diseases during the COVID-19 pandemic:Manifestations,mechanism and management显示文摘Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)is considered the causative pathogen of coronavirus disease 2019(COVID-19)and has become an international danger to human health.Although respiratory transmission and symptoms are still the essential manifestations of COVID-19,the digestive system could be an unconventional or supplementary route for COVID-19 to be transmitted and manifested,most likely due to the presence of angiotensin-converting enzyme 2(ACE2)in the gastrointestinal tract.In addition,SARS-CoV-2 can trigger hepatic injury via direct binding to the ACE2 receptor in cholangiocytes,antibodydependent enhancement of infection,systemic inflammatory response syndrome,inflammatory cytokine storms,ischemia/reperfusion injury,and adverse events of treatment drugs.Gastrointestinal symptoms,including anorexia,nausea,vomiting,and diarrhea,which are unusual in patients with COVID-19,and some digestive signs may occur without other respiratory symptoms.Furthermore,SARS-CoV-2 can be found in infected patients’stool,demonstrating the likelihood of transmission through the fecal-oral route.In addition,liver function should be monitored during COVID-19,particularly in more severe cases.This review summarizes the evidence for extra-pulmonary manifestations,mechanisms,and management of COVID-19,particularly those related to the gastrointestinal tract and liver. | Dina Zakaria Mohamed Mai El-Sayed Ghoneim Sally El-Sayed Abu-Risha Ramy Ahmed Abdelsalam Mohamed Abdelhalem Farag | 2021 | World Journal of Gastroenterology2021，27，28： | 2 |
| 5 | The Trauma of Awareness: History, Clinical Features, Risk Factors, and Cost显示文摘 | Mohamed Ghoneim | 2010 | Anesthesia & Analgesia2010，，3： | 2 |
| 6 | Comparison of psychologic and cognitive functions after general or regional anesthesia 显示文摘 | Ghoneim M M Hi nrichs JV O'Hara MW | 1988 | Anesthesiology1988，69，4： | 1 |
| 7 | Optic disc detection from normalized digital fundus images by means of a vessels' direction matched filter 显示文摘 | Youssif A Ghalwash A Ghoneim A | 2008 | IEEE Transactions on Medical Imaging2008，27，1： | 1 |
| 8 | Extended Radical Lymphadenectomy in patients with urothelial bladder cancer: results of a prospective multi center study显示文摘 | Leissner J Ghoneim M A Abol-Enein H | 2004 | J Urol2004，171，： | 1 |
| 9 | Optic disc detection from normalized digital fundus images by means of a vessels' direction matched filter显示文摘 | Youssif AR Ghalwash AZ Ghoneim AR | 2008 | IEEE Transactions on Medical Imaging2008，27，1： | 1 |
| 10 | Obstructive jaundice promotes intestinal-barrier dysfunction and bacterial translocation : experimental study 显示文摘 | Abdeldayem H Ghoneim E Refaei AA | 2007 | Hepatol Int2007，1，4： | 1 |
| 11 | Incorporation of density relaxation in the analysis of residual stresses in molded parts显示文摘 | H GHONEIM C A HIEBER | 1997 | Polymer Engineering and Science1997，37，1： | 1 |
| 12 | Computed tomographic evaluation of canal shape instrumented by different kinematics rotary nickel-titanium systems显示文摘 | Marzouk AM Ghoneim AG | 2013 | J Endod2013，39，7： | 1 |
| 13 | Epidermal growth factor stimulates matrix metalloproteinase-9 expression and invasion in human follicular thyroid carcinoma cells through Focal adhesion kinase显示文摘 | Rothhut B Ghoneim C Antonicelli F | 2007 | Biochimic2007，89，5： | 1 |
| 14 | Speed of recovery and side-effect profile of sevoflurane sedation compared with midazolam显示文摘 | Ibrahim AE Ghoneim MM Kharasch ED | | 0，，01： | 1 |
| 15 | Bridging long ureteral defects using theYang-Monti principle显示文摘 | Ali-El-Dein B Ghoneim Ma | | 0，，03： | 1 |
| 16 | Response of a laminar premixed flame to flow oscillations: A kinematic model and thermoacoustic instability results显示文摘 | Fleifil M Annaswamy A M Ghoneim Z A | 1996 | Combustion and Flame1996，106，4： | 1 |
| 17 | Voltammetric studies and assay of the antiiflammatory drug ketoprofen in pharmaceutical formulation and human plasma at a mercury electrode显示文摘 | GHONEIM M M TAWFI K | 2003 | Can J Chem2003，81，： | 1 |
| 18 | Sequence,characterization and localization of a cysteine proteinase cathepsin L in Schistosoma mansoni显示文摘 | Michel A Ghoneim H Resto M | 1995 | Mol Biochem Parasitol1995，73，： | 1 |
| 19 | Tuberculosis in Egyptian kidney trasplant recipients:study of clinical couse and outcome显示文摘 | el-Agroudy A E Refaie A F Moussa O M Ghoneim -M-A | 2003 | J Nephrol2003，16，3： | 1 |
| 20 | Resistance to fracture of roots obturated with novel canal-filling systems 显示文摘 | Ghoneim AG Lutfy RA Sabet NE | 2011 | J Endod2011，37，11： | 1 |
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