|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Overlapping expression of microRNAs in human embryonic colon and colorectal cancer显示文摘MicroRNAs (miRNAs ) 为调整房间区别并且维持干细胞的 pluripotent 状态是必要的。尽管特定的 miRNAs 的 dysregulation 与癌症的某些类型被联系了,到日期,没有证据连接了 miRNA 表示在胚胎并且肿瘤纸巾。我们在人的胚胎的结肠组织,并且在 colorectal 癌症估计了成熟 miRNAs 的表示并且配对正常结肠组织。重叠 miRNA 表示在胚胎的结肠的 mucosa 和 colorectal 癌症之间被检测。我们发现了 miR-17-92 聚类,调整在两个盒子中的房间增长并且它的目标, E2F1,在人的冒号开发和结肠的 carcinogenesis 展出表示的一个类似的模式。在 situ,杂交在地窟祖先分隔空间证实了 miR-17-5p 的表示的高水平。我们断定 miRNA 小径在胚胎的开发和结肠的上皮的肿瘤的转变起一个主要作用。 | Mariano Monzo Alfons Navarro Eva Bandres Rosa Artells Isabel Moreno Bemat Gel Rafael Ibeas Jose Moreno Francisco Martinez Tania Diaz Antonio Martinez Olga Balague Jesus Garcia-Foncillas | 2008 | Cell Research2008，18，8： | 32 |
| 2 | 电流强化铝合金CO_2激光焊接显示文摘介绍了一种利用电流的磁流体动力学效应强化铝合金CO2 激光焊接的方法及初步试验结果。在激光焊接过程中 ,通过一个布置于熔池前方的附加电极向熔池提供电流 ,该电流在熔池中产生磁场和电磁力 ,致使熔池运动状态及相应的热交换条件发生改变 ,从而提高激光能量的有效利用率和加工效率、控制焊缝成型。利用该方法 ,焊缝深度最高增加约 32 % ,面积增加约 2 0 % ,而焊缝宽度减小约 2 8% | 肖荣诗 左铁钏 Gnter Ambrosy Helmut Hgel | 2004 | 中国激光2004，31，3： | 22 |
| 3 | 在革新与现代主义之间:夏昌世与德国(英文)显示文摘夏昌世,中国第一代建筑师,1920年代在德国卡尔斯鲁厄留学。1932年,他在图宾根完成了博士论文之后重返祖国。1940年代后期,他在广州成为教授,1973年与妻子一同重返德国,并在那里生活直至1996年逝世。他的设计方法不仅受到那个时代欧洲现代主义运动氛围的熏陶,还来自他对中国传统景观与建筑艺术历史的研究。他是引领岭南区域形成岭南学派建筑的主导力量之一。同时,作为一建筑学教授,他在广州培养了新一代青年建筑师。 | Eduard Kgel 杨力研 | 2010 | 南方建筑2010，，2： | 15 |
| 4 | 采用填充焊丝的外加电流铝合金CO_2激光焊接显示文摘在铝合金CO2激光焊接时,通过填充焊丝向焊接熔池注入外加电流,直流电源的一极与填充焊丝相连,另一极在熔池后方与工件相连,由此构成电流回路。研究结果表明,随着外加电流的增加,焊缝熔深和面积增大,且焊缝表面成形更加均匀,鱼磷纹更加细密,即外加电流提高了焊接效率,改善了焊接过程的稳定性。进一步研究表明,外加电流的电阻热对焊接结果的影响极小。外加电流对铝合金CO2激光焊接的影响归因于电流的磁流体效应。 | 肖荣诗 左铁钏 Ambrosy G Hügel H | 2006 | 焊接学报2006，27，5： | 7 |
| 5 | Influence of Gd doping on the absolute quantum efficiency and lifetime of Eu_xGd_(1-x)(TTA)_3 phens显示文摘Absolute quantum yield(Φ) is one of the most important parameters to evaluate the potential of novel materials.Lanthanide complexes Eu_xGd_(1-x)(TTA)3phens are synthesized with the ratio of Gd^(3+) dopant concentration ranging from 10%to 90%to improve the absolute quantum yield.Eu_xGd_(1-x)(TTA)_3phens possess similar infrared and ultraviolet spectra,showing that they have similar molecular structures.The absolute emission quantum yields of Eu_xGd_(1-x)(TTA)_3phens are determined using a fluoromax-4spectrofluorometer equipped with an integrating sphere.The fluorescence lifetimes of the Eu_xGd_(1-x)(TTA)_3phens are measured in the same experiment.It was found that both absolute quantum yields and fluorescence lifetimes of Eu_xGd_(1-x)(TTA)_3phens are of quasi-periodic variation with the change of the Gd^(3+)dopant concentrations.The absolute quantum efficiency and fluorescence lifetime vary with respect to the Gd content in an opposite fashion,indicating that the rate of energy absorption by the Eu_xGd_(1-x)(TTA)_3phens and the conversion to light energy is critical for the absolute quantum efficiency.The radiative rate constant K_r and non-radiative rate constant K_(nr) are calculated.The dependence of K_r and K_(nr) on the Gd^(3+) dopant concentrations is very similar to that of absolute quantum efficiency.The radiation rate constant K_r and absolute quantum efficiency have a linear relationship. | Ting-Ting Dai Lei Liu Dong-Liang Tao Shi-Gang Li HongZhang Yu-Min Cui Yong-Zhong Wang Ji-Tang Chen Kun Zhang Wen-Zhong Sun Xiao-Yun Zhao gel Liu | 2014 | Chinese Chemical Letters2014，25，6： | 6 |
| 6 | Calcitriol analog ZK191784 ameliorates acute and chronic dextran sodium sulfate-induced colitis by modulation of intestinal dendritic cell numbers and phenotype显示文摘AIM: To investigate the effects of ZK1916784, a low calcemic analog of calcitriol on intestinal inflammation. METHODS: Acute and chronic colitis was induced by dextran sodium sulfate (DSS) according to standard procedures. Mice were treated intraperitoneally with ZK1916784 or placebo and colonic inflammation was evaluated. Cytokine production by mesenterial lymph node (MLN) cells was measured by ELISA. Immunohistochemistry was performed to detect intestinal dendritic cells (DCs) within the colonic tissue, and the effect of the calcitriol analog on DCs was investigated. RESULTS: Treatment with ZK191784 resulted in significant amelioration of disease with a reduced histological score in acute and chronic intestinal inflammation. In animals with acute DSS colitis, down- regulation of colonic inflammation was associated with a dramatic reduction in the secretion of the proinflammatory cytokine interferon (IFN)-γ and a significant increase in intereleukin (IL)-10 by MLN cells. Similarly, in chronic colitis, IL-10 expression in colonic tissue increased 1.4-fold when mice were treated with ZK191784, whereas expression of the Th1-specific transcription factor T-beta decreased by 81.6%. Lower numbers of infiltrating activated CD11c+ DCs were found in the colon in ZK191784-treated mice with acute DSScolitis, and secretion of proinflammatory cytokines by primary mucosal DCs was inhibited in the presence of the calcitriol analog. CONCLUSION: The calcitriol analog ZK191784 demonstrated significant anti-inflammatory properties in experimental colitis that were at least partially mediated by the immunosuppressive effects of the derivate on mucosal DCs. | Ulrike G Strauch Florian Obermeier Nicole Grunwald Nadja Dunger Heiko C Rath Jürgen Schlmerich A Steinmeyer U Zügel HH Herfarth | 2007 | World Journal of Gastroenterology2007，13，48： | 4 |
| 7 | Galectin-3:an open-ended story显示文摘 | DUMIC J DABELIC S FLGEL M | 2006 | Biochim Biophys Acta2006，1760，4： | 1 |
| 8 | Hierarchical crosstraining in work-in-process-constrained systems 显示文摘 | Gel E S Hopp W J Van Oyen M P | 2007 | lie Transactions2007，39，2： | 1 |
| 9 | Involvement of c-Myc in growth inhibition of Hep 3B human hepatoma cells by a vitamin K analog显示文摘 | Gel Wang Z | 2004 | J Hepatol2004，41，5： | 1 |
| 10 | Vitamin D : a growing per- spective显示文摘 | Kimball S FuleihaJ1 Gel - H Vieth R | 2008 | Crit Rev Clin Lab Sci2008，45，4： | 1 |
| 11 | Charges in heparinsulfate correlate with increased glomerular permeabilily 显示文摘 | Stevenson J Hovingh P | 1988 | Kindney Int1988，33，： | 1 |
| 12 | A retrospective analysis显示文摘 | Mandracchia VJ Sanders SM Frerichs JA The use of becaplermin (rhPDGF BB) gel for chronic no healing ulcers | 2001 | Clin Podiatr Med Surg2001，18，1： | 1 |
| 13 | Novel, anionic, ao- tiviral septapeptidcs from mosquito cells also protect monkey cells against dengue virus显示文摘 | Lausulttfipong C Kanthong N Fh'gel T W | 2013 | Antiviral Res2013，98，3： | 1 |
| 14 | Laparoscopic Approach to Colorectal Procedures in the Obese Patient: Risk Factor or Benefit?显示文摘 | Hubert Scheidbach Frank Benedix Omar Hügel Daniela Kose Ferdinand K?ckerling Hans Lippert | 2007 | Obesity Surgery2007，，1： | 1 |
| 15 | Marangoni effect in laser deep penetration welding of steel显示文摘 | T Fuhrich P Berger H Hügel | 2001 | Journal of Laser Applications2001，13，5： | 1 |
| 16 | Modulated beam confonual thera- py for head and neck tumors 显示文摘 | Boyer AL Gels P Grant W | 1997 | lnt J Radiat Oncol Biol Phys1997，39，1： | 1 |
| 17 | Modulation of porosity in apatitic cements by the use of alpha-tricalcium phosphate-calcium sulphate dihydrate mixtures 显示文摘 | Femandez E Vlad M D Gel M M | 2005 | Biomaterials2005，26，17： | 1 |
| 18 | Quality and authenticity control of fruit purées,fruit preparations and jams:a review显示文摘 | F(U)GEL R CARLE R SCHIEBER A | 2005 | Trends in Food Science & Technology2005，16，： | 1 |
| 19 | 显示文摘 | NILSSON C VIBERG P SP(E)GEL P JOERNTEN-KARLSSON M PETERSSON P NILSSON S | 2006 | Anal Chem2006，78，17： | 1 |
| 20 | Update on clinical developments with celecoxib, a new specific COX-2 inhibitor: what can we expect 显示文摘 | Gels GS | 1999 | J Rheumatol1999，56，1： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员