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| 1 | Relationship between Crohn’s disease, infection with Mycobacterium avium subspecies paratuberculosis and SLC11A1 gene polymorphisms in Sardinian patients显示文摘AIM: To study the association between Crohn’s disease (CD), Mycobacterium avium subspecies paratubercu- losis (MAP), and genetic factors by examining the role of natural resistance-associated macrophage protein 1 (NRAMP1) gene polymorphisms (now SLC11A1) in Sar dinian patients with CD and controls. METHODS: Thirty-seven CD patients and 34 controls with no inflammatory bowel disease (IBD) were recruited at the University of Sassari after giving written con sent. Six SCL11A1 polymorphisms previously reported to be the most significantly associated with IBD were searched. M. paratuberculosis was identified by IS900 PCR and sequencing. Logistic regression was used to cal culate odds ratios (OR) for the associations among CD presence of MAP, and 6 loci described above. RESULTS: For the first time, a strong association was observed between polymorphisms at NRAMP1 locus 823C/T and CD. While CD was strongly associated withboth NRAMP1 and MAP, NRAMP1 polymorphisms and MAP themselves were not correlated. CONCLUSION: Combined with previous work on the NOD2/CARD15 gene, it is clear that the interplay of ge- netic, infectious, and immunologic factors in the etiology of CD is complex. | Leonardo A Sechi Maria Gazouli Lee E Sieswerda Paola Molicotti Niyaz Ahmed John Ikonomopoulos Antonio M Scanu Daniela Paccagnini Stefania Zanetti | 2006 | World Journal of Gastroenterology2006，12，44： | 3 |
| 2 | Current insights in to the pathophysiology of irritable bowel syndrome 显示文摘 | KARANTANOS T MARKOUTSAKI T GAZOULI M | 2010 | Gut Pathog2010，132，1： | 1 |
| 3 | Effect of mono-ethylhexyl phthalate on MA-10 Leydig tumor cells 显示文摘 | Dees JH Gazouli M Papadopoulos V | 2001 | Reproductive Toxicology2001，，： | 1 |
| 4 | Effect of mono-ethylhexyl phthalate on MA-10 Leydig tumor cells显示文摘 | Dees J H Gazouli M Papadopoulos V | 2001 | Reprod Toxicol2001，15，2： | 1 |
| 5 | Role of functional polymorphisms of NRAMP1 gene for the de- velopment of Crohn' s disease 显示文摘 | Gazouli M Atsaves V Mantzaris G | 2008 | Inflamm Bowel Dis2008，14，10： | 1 |
| 6 | Gestational diabetes mellitus shares polymorphisms of genes associated with insulin resistance and type 2 diabetes in the Greek population显示文摘 | Pappa KI Gazouli M Economou K et a1 | 2011 | Gynecol Endocrinol2011，27，4： | 1 |
| 7 | Transferable class C beta-lactamases in Escherichia coli strains isolated in Greek hospitals and characterization of two enzyme variants (LAT-3 and LAT-4) closely related to Citrobacter freundii AmpC beta-lactamase 显示文摘 | Gazouli M Tzouvelekis L S Vatopoulos A C | 1998 | Antimicrob Agents Chemother1998，42，4： | 1 |
| 8 | Genetic variants in TCFTL2 and KCNJ11 genes in a Greek population with polycystic ovary syndrome显示文摘 | Christopoulos P Mastorakos G Gazouli M | 2008 | Gynecol Endocrinol2008，24，9： | 1 |
| 9 | Expression of microRNAs, miR-21, miR-31, miR-122, miR-145, miR-146a, miR- 200c, miR-221, miR-222, and miR-223 in patients with hepatocellu- lar carcinoma or intrahepatic cholangiocarcinoma and its prognostic sig- nificance 显示文摘 | Karakatsanis A Papaconstantinou I Gazouli M | 2013 | Mol Carcinog2013，52，4： | 1 |
| 10 | 5 - HT2A receptor gene polymorphisms and irritable bowel syndrome 显示文摘 | Markoutsaki T Karantanos T Gazouli M | 2011 | J Clin Gastroenterol2011，45，6： | 1 |
| 11 | Survivin-31G/C promoterpolymorphism and sporadic colorectal cancer显示文摘 | Gazouli M Tzanakis N Rallis G | | 0，，02： | 1 |
| 12 | A review on the role of microRNA in biology, diagnosis, and treatment of pancreatic adenocarcinoma 显示文摘 | Papaconstantinous IG Lykoudis PM Gazouli M | 2012 | Pancreas2012，41，： | 1 |
| 13 | Effect of mono- ethylhexyl phthalate on MA-10 Leydig tumor cells显示文摘 | Dees JH Gazouli M Papadopoulos V | 2001 | Reprod Toxicol2001，15，2： | 1 |
| 14 | Vascular endothelial growth factor polymorphisms in gastric cancer development, prognosis and survival显示文摘 | Tzanakis N Gazouli M Rallis G | 2006 | J Surg Oncol2006，94，7： | 1 |
| 15 | Transferable cefoxitin resistance in enterobacteria from Greek hospitals and characterization of a plasmid- mediated group 1 beta- lactamase (LAT- 2)显示文摘 | Gazouli M Tzouvelekis L S Prinarakis E | 1996 | Antimicrob Agents Chemother1996，40，7： | 1 |
| 16 | Sequence of the gene encoding a plasmid-mediated cefotaxime-hydrolyzing classA β-lactamase (CTX-M-4): involvement of serine 237 in cephalosporin hydrolysis显示文摘 | Gazouli M Tzelepi E Sidorenko SV | 1998 | Antimicrob Agents Chemother1998，42，5： | 1 |
| 17 | Polymo- rphisms of caspase 8 and caspase 9 gene and colorectal cancer susceptibility and prognosis 显示文摘 | Theodoropoulos GE Gazouli M Vaiopoulou A | 2011 | Int J Colorectal Dis2011，26，9： | 1 |
| 18 | Effect of mono-ethylhexyl phthalate on MA-10 |eydig tumor cells显示文摘 | DEES J H GAZOULI M PAPADOPOULOS V | 2001 | Reproductive Toxicology2001，，15： | 1 |
| 19 | Comparative evaluation of the inhibitory activities of the novel penicillanic acid sulfone Ro 48- 1220 against β- lactamases that belong to groups 1,2b,and 2be显示文摘 | Tzouvelekis L S Gazouli M Poinarakis E E | 1997 | Antimicrob Agents Chemother1997，41，2： | 1 |
| 20 | Transferable cefoxitin resistance in enterobacteria from Greek hospitals and characterization of a plasmid-mediated group1 β-lactamase (LAT-2)显示文摘 | Tzouvelekis LS Prinarakis E | 1996 | Antimicrob Agents Chemother1996，40，： | 1 |
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