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| 1 | Rapid human melanoma cell deathinduced by sanguinarine throughoxidative stress显示文摘 | Burgeiro A Bento AC Gajate C | 2013 | Eur J Pharmacol2013，705，13： | 1 |
| 2 | A transduetive neu- to-fuzzy controller: application to a drilling process显示文摘 | GAJATE A HABER RE VEGA PI | 2010 | IEEE Trans Neural Netw2010，21，7： | 1 |
| 3 | Inflammatory pseudotmnor of mediastinum treated with tomotherapy and monitored with FDG-PET/CT: case report and literature review 显示文摘 | Alongi F Bolognesi A Samanes Gajate AM | 2010 | Tumori2010，96，2： | 1 |
| 4 | Involvement of mitochondria and caspase-3 in ET-18-OCH3 induced apoptosis of human leukemia cells显示文摘 | Gajate C Santos Beneit AM Macho A | 2000 | Int J Cancer2000，86，2： | 1 |
| 5 | Involvement of mitochondria and caspase- 3 in ET- 18 - OCH3 - induced apoptosis of human leukemic cells 显示文摘 | Gajate C Santos- Beneit AM Macho A | 2000 | Int J Cancer2000，86，2： | 1 |
| 6 | Intemal model control based ona neurofuzzy system for network applications,a case studyon the high-performance drilling process显示文摘 | Gajate A M Guerra R E H | 2009 | IEEE Transactionson Automation Science and Engineering2009，6，2： | 1 |
| 7 | Rapid human melanoma cell death induced by sanguinarine through oxidative stress 显示文摘 | Burgeiro A Bento A C Gajate C | 2013 | EurJ Pharmacol2013，705，13： | 1 |
| 8 | Inflammatory pseudotumor of mediastinum treated with tomotherapy and monitored with FDG-PET/CT:case report and literature review显示文摘 | Alongi F Bolognesi A Gajate AM | | 0，，02： | 1 |
| 9 | Involvement of mitochondria and Caspase-3 in ET-18-OCH3 induced apoptosis of human leukemia cells显示文摘 | Gajate C Santos Benecit AM Macho A | 2000 | Int J Cancer2000，86，2： | 1 |
| 10 | Induction of apoptosis in human mitogen-activated peripheral blood T-lymphocytes by the ether phospholipid ET-18-OCH3:involvement of the Fas receptor/ligand system显示文摘 | Gajate C Macho A | 1999 | Br J Pharmacol1999，127，4： | 1 |
| 11 | Involvement of mitochondria and caspase-3 in ET-18-OCH(3)-induced apoptosis of human leukemic cells 显示文摘 | Gajate C Santos Beneit AM Macho A | 2000 | Int J Cancer2000，86，： | 1 |
| 12 | Inflammatory pseudotu- mor of mediastinum treated with tomotherapy and monitored with FDG-PET/CT: case report and literature review 显示文摘 | Alongi F Bolognesi A Gajate AM | 2010 | Tumori2010，96，2： | 1 |
| 13 | Involvement of mitochondria and caspase-3 in ET-18-OCH3-induced apoptosis of human leukemic cells显示文摘 | Gajate C SantosBeneit AM Macho A | 2000 | Int J Cancer2000，86，2： | 1 |
| 14 | Involvement of mitochondria and Caspase-3 in ET-18-OCH(3)-induced apoptosis of human leukemic cells显示文摘 | Gajate C Santos-Beneit A M Macho A | 2000 | Int J Cancer2000，86，2： | 1 |
| 15 | Involvement of mitochondria and Caspase 3 in ET-18-OCH3-induced apoptosis of human leukemia cells显示文摘 | Gajate C Santos-Beneit AM Macho A | 2000 | Int J Cancer2000，86，： | 1 |
| 16 | Inflammatory pseudotumor of mediastinum treated with tomotherapy and monitored with FDG-PET/CT:case report and literature review显示文摘 | Alongi F Bolognesi A Gajate AM | 2010 | Tumori2010，96，2： | 1 |
| 17 | Health-related quality of life and stress-related disorders in COVID-19 ICU survivors:Are they worse than with other causes of ARDS?显示文摘Background:There are insufficient data regarding the impact of acute respiratory distress syndrome related to coronavirus disease 2019(C-ARDS)–caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)–on health-related quality of life(HRQoL)and the occurrence of stress-related disorders in coronavirus disease 2019(COVID-19)intensive care unit(ICU)survivors.The aim of this study is to assess HRQoL and the occurrence of stress-related disorders(acute stress disorder[ASD]and post-traumatic stress disorder[PTSD])in C-ARDS ICU survivors at 1 and 6 months following hospital discharge.Methods:This prospective observational study included 90 patients treated for C-ARDS between March and May 2020 in the ICU and discharged alive from the hospital.All patients included in the study were contacted by telephone 1 month and 6 months post-hospital discharge to assess the presence of symptoms of stress-related disorders and HRQoL using the 8-item Treatment Outcome Post-traumatic Stress Disorder scale(TOP-8)and 36-item Short Form survey(SF-36).We performed univariate analyses to evaluate differences between patients who developed stress and those who did not.We also compared SF-36 scores in our sample with data from the general Spanish population and from cohorts of non–C-ARDS and severe acute respiratory syndrome coronavirus-1(SARS-CoV-1)survivors.Results:There are 24.1%of patients showed symptoms of ASD;in 13.5%of cases the symptoms persisted 6 months later.Risk factors for the development of symptoms of ASD and PTSD are younger age,female sex,obesity,a previously diagnosed psychiatric disease and disease severity at ICU admission(P<0.05).HRQoL was greatly affected by C-ARDS;however,there was improvement on all scales of the SF-36 at the 6-month follow-up(P<0.05).The mean SF-36 score of our sample was higher than those previously reported in non–C-ARDS survivors(P<0.05)for physical functioning(78.0 vs.52.0),role functioning/physical(51.0 vs.31.0),bodily pain(76.1 vs.57.0),vitality(58.6 vs.48.0),social function(72.6 vs.63.0)and role emotional(77.4 vs.55.0),except on the general health scale.C-ARDS survivors also scored better than SARS-CoV-1 survivors on all scales except for body pain(P<0.05).Conclusions:The impact of C-ARDS on HRQoL is substantial,with frequent occurrence of PTSD symptoms.Patients are heavily affected in all areas of health in the first month of post-hospital discharge but show a dramatic improvement within 6 months,especially in terms of physical health. | Diego Gil Carlos Tiscar Maria Gómez Javier Felices Luis Gajate Patricia Fernandez David Pestaña Tommaso Bardi | 2022 | Journal of Intensive Medicine2022，2，2： | 0 |
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