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1Maize-soybean strip intercropping: Achieved a balance between high productivity and sustainability显示文摘Intercropping is one of the most vital practice to improve land utilization rate in China that has limited arable land resource. However, the traditional intercropping systems have many disadvantages including illogical field lay-out of crops, low economic value, and labor deficiency, which cannot balance the crop production and agricultural sustainability. In view of this, we developed a novel soybean strip intercropping model using maize as the partner, the regular maize-soybean strip intercropping mainly popularized in northern China and maize-soybean relay-strip intercropping principally extended in southwestern China. Compared to the traditional maize-soybean intercropping systems, the main innovation of field lay-out style in our present intercropping systems is that the distance of two adjacent maize rows are shrunk as a narrow strip, and a strip called wide strip between two adjacent narrow strips is expanded reserving for the growth of two or three rows of soybean plants. The distance between outer rows of maize and soybean strips are expanded enough for light use efficiency improvement and tractors working in the soybean strips. Importantly, optimal cultivar screening and increase of plant density achieved a high yield of both the two crops in the intercropping systems and increased land equivalent ratio as high as 2.2. Annually alternative rotation of the adjacent maize-and soybean-strips increased the grain yield of next seasonal maize, improved the absorption of nitrogen, phosphorus, and potasium of maize, while prevented the continuous cropping obstacles. Extra soybean production was obtained without affecting maize yield in our strip intercropping systems, which balanced the high crop production and agricultural sustainability.DU Jun-bo HAN Tian-fu GAI Jun-yi YONG Tai-wen SUN Xin WANG Xiao-chun YANG Feng LIU Jiang SHU Kai LIU Wei-guo YANG Wen-yu 2018Journal of Integrative Agriculture2018,17,4:34
2Evaluation of the suitability of a partially defatted black soldier fly (Hermetia illucens L.) larvae meal as ingredient for rainbow trout (Oncorhynchus mykiss Walbaum) diets显示文摘Background: Two trials were performed to evaluate a partially defatted Hermetia illucens(HI) larvae meal as potential feed ingredient in rainbow trout(Oncorhynchus mykiss Walbaum) diets. In the first trial, 360 trout(178.9 ± 9.8 g of mean initial body weight) were randomly divided into three experimental groups(4 tanks/treatment, 30 fish/tank). The fish were fed for 78 days with isonitrogenous, isolipidic and isoenergetic diets containing increasing levels of HI, on as fed basis: 0%(HI0, control diet), 25%(HI25) and 50%(HI50) of fish meal substitution, corresponding to dietary inclusion levels of 0, 20% and 40%. In the second trial, 36 trout(4 tanks/treatment, 3 fish/tank) were used to evaluate the in vivo apparent digestibility coefficients(ADC) of the same diets used in the first trial.Results: Survival, growth performance, condition factor, somatic indexes, and dorsal fillet physical quality parameters were not affected by diet. The highest dietary inclusion of HI larvae meal increased dry matter and ether extract contents of trout dorsal fillet. The use of HI larvae meal induced a decrease of valuable polyunsaturated fatty acids(PUFA) even if differences were only reported at the highest level of HI inclusion. The insect meal worsened the lipids health indexes of the same muscle. Dietary inclusion of insect meal did not alter the villus height of the fish. No differences were found among treatments in relation to ADC of ether extract and gross energy, while ADC of dry matter and crude protein were higher in HI25 if compared to HI50.Conclusions: The obtained results showed that a partially defatted HI larvae meal can be used as feed ingredient in trout diets up to 40% of inclusion level without impacting survival, growth performance, condition factor, somatic indexes, dorsal fillet physical quality parameters, and intestinal morphology of the fish. However, further investigations on specific feeding strategies and diet formulations are needed to limit the observed negative effects of the insect meal on the FA composition of dorsal muscle.M. Renna A. Schiavone F. Gai S. Dabbou C. Lussiana V. Malfatto M. Prearo M. T. Capucchio I. Biasato E. Biasibetti M. De Marco A. Brugiapaglia I. Zoccarato L. Gasco 2017Journal of Animal Science and Biotechnology2017,8,4:32
3Black soldier fly defatted meal as a dietary protein source for broiler chickens:Effects on growth performance,blood traits,gut morphology and histological features显示文摘Background: The present study has evaluated the effects of different inclusion levels of a partially defatted black soldier fly(Hermetia illucens L.; HI) larva meal on the growth performance, blood parameters and gut morphology of broiler chickens. A total of 256 male broiler chickens(Ross 308) were reared from d 1 to d 35 and assigned to4 dietary treatments(8 replicates/treatment and 8 birds/replicate). HI larva meal was included at increasing levels(0, 5%, 10% and 15%; HI0, HI5, HI10 and HI15, respectively) in isonitrogenous and isoenergetic diets formulated for 3 feeding phases: starter(1–10 d), growing(10–24 d) and finisher(24–35 d). Two birds per pen were slaughtered at d 35 and morphometric investigations and histopathological alterations were performed.Results: The live weight(LW) showed linear and quadratic responses to increasing HI larva meal(maximum for HI10 group). Average daily gain(ADG) showed a linear and quadratic responses to HI meal(maximum for HI10 group) during starter and growing periods. A linear decrease was observed for ADG during the finisher period. The daily feed intake(DFI) showed a linear and quadratic effect during the starter period(maximum for HI10 group).Linear and quadratic responses were observed for the feed conversion ratio(FCR) in the growing period and for the whole period of the experiment. The FCR showed a linear response in the finisher period(maximum for HI15).No significant effects were observed for the blood and serum parameters, except for the phosphorus concentration,which showed linear and quadratic responses as well as glutathione peroxidase(GPx) activity, the latter of which showed a linear response. The HI15 birds showed a lower villus height, a higher crypt depth and a lower villus height-to-crypt depth ratio than the other groups.Conclusions: Increasing levels of dietary HI meal inclusion in male broiler chickens may improve the LW and DFI during the starter period, but may also negatively affect the FCR and gut morphology, thus suggesting that low levels may be more suitable. However, no significant effects on the haematochemical parameters or histological findings were observed in relation to HI meal utilization.Sihem Dabbou Francesco Gai Ilaria Biasato Maria Teresa Capucchio Elena Biasibetti Daniela Dezzutto Marco Meneguz Iveta Plachà Laura Gasco Achille Schiavone 2018Journal of Animal Science and Biotechnology2018,9,4:34
4Main controlling factors and enrichment area evaluation of shale gas of the Lower Paleozoic marine strata in south China显示文摘The Lower Paleozoic shale in south China has a very high maturity and experienced strong tectonic deformation. This character is quite different from the North America shale and has inhibited the shale gas evaluation and exploration in this area. The present paper reports a comprehensive investigation of maturity, reservoir properties,fluid pressure, gas content, preservation conditions, and other relevant aspects of the Lower Paleozoic shale from the Sichuan Basin and its surrounding areas. It is found that within the main maturity range(2.5 %3.5 %) is considered a high risk for shale gas exploration. Taking the southern area of the Sichuan Basin and the southeastern area of Chongqing as examples of uplifted/folded and faulted/folded areas, respectively, geological models of shale gas content and loss were proposed.For the uplifted/folded area with a simple tectonic deformation, the shale system(with a depth >2000 m) has largely retained overpressure during uplifting without a great loss of gas, and an industrial shale gas potential is generally possible. However, for the faulted/folded area with a strong tectonic deformation, the sealing condition of the shalesystem was usually destroyed to a certain degree with a great loss of free gas, which decreased the pressure coefficient and resulted in a low production capacity. It is predicted that the deeply buried shale(>3000 m) has a greater gas potential and will become the focus for further exploration and development in most of the south China region(outside the Sichuan Basin).Xian-Ming Xiao Qiang Wei Hai-Feng Gai Teng-Fei Li Mao-Lin Wang Lei Pan Ji Chen Hui Tian 2015Petroleum Science2015,12,4:27
5Nutritional value of a partially defatted and a highly defatted black soldier fly larvae (Hermetia illucens L.) meal for broiler chickens: apparent nutrient digestibility,apparent metabolizable energy and apparent ileal amino acid digestibility显示文摘Background: The study aimed to determine the apparent total tract digestibility coefficients(ATTDC) of nutrients, the apparent metabolizable energy(AME and AMEn) and the amino acid(AA) apparent ileal digestibility coefficients(AIDC)of a partially defatted(BSFp) and a highly defatted(BSFh) black soldier fly larvae meal. The experimental diets were: a basal diet and two diets prepared by substituting 250 g/kg(w/w) of the basal diet with BSFp or BSFh, respectively.Results: Significant differences were found between BSFp and BSFh meals for ATTDC of the nutrients: BSFp resulted more digestible than BSFh, except for ATTDC of CP which did not differed between meals, while a statistical trend was observed for ATTDC of DM and EE. The AME and AMEn values were significantly(P < 0.05) different between the two BSF meals, with higher levels for BSFp(16.25 and 14.87 MJ/kg DM, respectively). The AIDC of the AA in BSFp ranged from 0.44 to 0.92, while in BSFh they ranged from 0.45 to 0.99. No significant differences were observed for the AA digestibility(0.77 and 0.80 for BSFp and BSFh, respectively), except for glutamic acid, proline and serine that were more digestible in the BSFh meal(P < 0.05).Conclusions: Defatted BSF meals can be considered as an excellent source of AME and digestible AA for broilers with a better efficient nutrient digestion. These considerations suggested the effective utilization of defatted BSF larvae meal in poultry feed formulation.Achille Schiavone Michele De Marco Silvia Martínez Sihem Dabbou Manuela Renna Josefa Madrid Fuensanta Hernandez Luca Rotolo Pierluca Costa Francesco Gai Laura Gasco 2017Journal of Animal Science and Biotechnology2017,8,4:27
6Kinetics of the leaching of TiO_2 from Ti-bearing blast furnace slag显示文摘Ti-bearing blast furnace slag is a valuable secondary resource containing about 24 percent of TiO2.In this paper a process of leaching Ti-bearing blast furnace slag with sulfuric acid to recover TiO2,and the kinetics of that reaction,are described.Under laboratory conditions the rate is controlled by a chemical reaction.The leaching reaction is in accord with a shrinking unre- acted-core model.The apparent reaction order of the leaching reaction was 1.222 and the apparent activation energy was 87.01 kJ/mol.The model fits the observed data well until 90%of the TiO2 has be leached from the particles.The model disagrees with observations during later periods of the reaction because the solution becomes supersaturated with Ti ions,which precipitate as H2TiO4.The assumptions of constant reactant concentration and that there is no effect from the product layer on diffusion,also cause the model to deviate from the actual values.LIU Xiao-hua GAI Guo-sheng YANG Yu-fen SUI Zhi-tong LI Li FU Jian-xia 2008Journal of China University of Mining and Technology2008,18,2:22
7Inheritance and Gene Mapping of Resistance to Soybean Mosaic Virus Strain SC14 in Soybean显示文摘大豆马赛克病毒(SMV ) 是世界范围的最广泛地分布式的疾病之一。它在大豆(甘氨酸最大(L.) Merr ) 引起严重收获损失和种子质量缺乏。从山西省孤立的 SMV 紧张 SC14,中国,是最新识别的剧毒的紧张并且能感染 Kefeng 号码 1,有宽光谱抵抗的来源。在现在的学习,大豆就职, PI96983, Qihuang 号码 1 和 Qihuang 号码 22 被识别是抵抗(R) andNannong 1138-2, Pixianchadou 易受影响的(S) 到 SC14。PI96983 x Nannong1138-2 的分离分析显示了那单个显性基因(指定了为 RSC14 ) 控制了抵抗到 SC14at V2 和 R1 发育阶段。一样的结果为 QihuangNo 的十字被获得。在 PI96983 x ,在 V2stage ,但是在 R1 的 Nannong 1138-2 上演的 1 个 x Nannong 1138-2 和 Qihuang 号码 22 x Nannong 1138-2 , F1 作为坏死(除马赛克以外的易受影响的症状)表现了,在 1R:2N:1S 的比率的 F2segregated ,并且坏死的(N) F2 个人的子孙在 R , N 和 S 也分离了。它显示了那单个基因(指定了为 RSC14Q,与那 ofPI96983 不同) 控制了抵抗到 SC14,它的优势与在 PI96983 x Nannong1138-2 一样(没有症状) 在 V2,在 R1 的舞台和并非一样上演。紧连接的 co-dominantsimple 顺序重复(SSR ) 标记 Satt334 显示所有异质接合的乐队完全相应于坏死的 F2 个人,否则所有坏死的 F2 个人是异质接合体。坏死力量由于在 SMV 紧张,抵抗基因,抵抗基因的遗传背景,和植物发展舞台之中的相互作用,这被推断。而且, SSR 标记的 bulked segregant 分析(BSA ) 被进行印射抵抗基因。在 PI96983 x Nannong 1138-2 的 F2,五个 SSR 标记, Sat_297, Sat_234, Sat_154, Sct_033 andSat_120,被发现仔细连接了到 RSC14 与 14.5 厘米, 11.3 厘米, 4.3 厘米, 3.2cM 和 6 厘米的遗传距离,分别地。在 Qihuang 号码 1 x Nannong 1138-2,三个 SSR 标记, Sat_234, Satt334 和 Sct_033 的 F2,紧分别地与 7.2 厘米, 1.4 厘米和 2.8 厘米的遗传距离连接了到 RSC14Q。由 Cregan 等基于综合联合地图。(1999 ) , RSC14 和 RSC14Q 与大豆的组 F 在 Sat_234 和 Sct_033 之间位于连接,分别地与他们在一样的方面的距离 fromSct_033 是 3.2 厘米和 2.8 厘米。因此, RSC14 和 RSC14Q 可能在一个一样的地点上。获得的信息在引起抵抗基因的节目并且好印射并且基于地图的克隆的大豆为抵抗基因的帮助标记的选择提供基本知识……Hai-Chao Li Hai-Jian Zhi Jun-Yi Gai Dong-Quan Guo Yan-Wei Wang Kai Li Li Bai Hua Yang 2006Journal of Integrative Plant Biology2006,48,12:19
8Partially defatted black soldier fly larva meal inclusion in piglet diets: effects on the growth performance, nutrient digestibility,blood profile, gut morphology and histological features显示文摘Background:The aim of this trial was to investigate the effects of different inclusion levels of a partially defatted black soldier fly (BSF,Hermetia illucens L.) larva meal on the growth performance,nutrient digestibility,blood profile,gut morphology and histological features of piglets.A total of 48 newly weaned piglets were individually weighed (initial body weight (IBW):6.1 ± 0.16 kg) and randomly allocated to 3 dietary treatments (4 boxes as replicates/treatment and 4 animals/box).BSF larva meal was included at increasing levels (0% [BSF0],5% [BSFS] and 10% [BSF10]) in isonitrogenous and isoenergetic diets formulated for two feeding phases:Ⅰ (from d 1 to d 23) and Ⅱ (from d 24 to d 61).The weight gain (WG),average daily gain (ADG),average daily feed intake (ADFI) and feed conversion ratio (FCR) were calculated for each feeding phase and for the whole trial.The haematochemical parameters and nutrient digestibility of the piglets were also evaluated.A total of 3 piglets per box were slaughtered on d 61 and the slaughtered piglets were submitted to morphometric investigations and histopathological examinations.Results:No overall significant differences were observed for growth performance (P > 0.05),except for the ADFI of phase Ⅱ,which showed a linear response to increasing BSF meal levels (P < 0.05,maximum for the BSF10 group).Dietary BSF meal inclusion did not significantly influence the blood profile,except as far as monocytes and neutrophils are concerned,and these showed a linear and quadratic response,respectively,to increasing BSF meal levels (P < 0.05,maximum for the BSF10 and BSF5 groups,respectively).On the other hand,the nutrient digestibility,gut morphology and histological features were not affected by dietary BSF meal inclusion (P > 0.05).Conclusions:The obtained results show that a partially defatted BSF larva meal can be used as a feed ingredient in diets for weaned piglets without negatively affecting their growth performance,nutrient digestibility,blood profile,gut morphology or histological features.Ilaria Biasato Manuela Renna Francesco Gai Sihem Dabbou Marco Meneguz Giovanni Perona Silvia Martinez Ana Cristina Barroeta Lajusticia Stefania Bergagna Luca Sardi Maria Teresa Capucchio Enrico Bressan Andrea Dama Achille Schiavone Laura Gasco 2019Journal of Animal Science and Biotechnology2019,10,3:19
9OSCILLATION CRITERIA FOR SECOND ORDER NONLINEAR DIFFERENTIAL EQUATIONS OF NEUTRAL TYPE显示文摘In this paper,the oscillation criteria for the solutions of the nonlinear differential equations of neutral type of the forms:[x(t)+p(t)x(σ(t))]″+q(t)f(x(τ(t)))g(x′(t))=0and[x(t)+p(t)x(σ(t))]″+q(t)f(x(t),x(τ(t)))g(x′(t))=0are obtained.Gai Mingjiu Shi Bao Zhang DecunDept.ofBasicSciences,NavalAeronauticalEngineeringAcademy,Yantai264001.* Correspondingauthor,e-mail:baoshi@public.ytptt.sd.c 2001Applied Mathematics(A Journal of Chinese Universities)2001,16,2:18
10Transplantation of autologous adipose-derived stem cells ameliorates cardiac function in rabbits with myocardial infarction显示文摘背景脂肪质导出干细胞(ADSC ) 能够在 vitro 区分进 cardiomyogenic 和 endothelial 房间。我们测试了假设那移植进心肌的疤的 ADSC 可以改革 infracted 心肌层并且恢复心脏的 function.Methods ADSC 从新西兰白人兔子的丰满的组织被孤立并且在 Iscove 的家有教养修改 dulbecco 的媒介。在兔子的左前面的下降冠的动脉的结扎以后的三个星期,也未经治疗的 ADSC 的接枝(UASC, n=14 ) , 5-azacytidine-pretreated ADSC (AASC, n=13 ) ,或磷酸盐缓冲区盐(n=13 ) 被注入梗塞区域。在在文化的房间 transplantation.Results ADSC 表明了像成纤维细胞的外观并且表示了 CD29, CD44 和 CD105 以后, Transmural 疤尺寸,心脏的功能,和 immunohistochemistry 5 个星期被执行。在房间移植以后的五个星期,在植入 AASC 的心的 transmural 疤尺寸比另外的 hearts.Many ADSC 的被区分进 cardiomyocytes 的小。在 prescar 的 AASC 出现了更多的象 myotube 一样。相反,在疤和 UASC 的中间的 AASC 糟糕被区分。一些 ADSC 被区分进 endothelial 房间并且参予像容器的结构形成。所有植入 ADSC 的心比的在梗塞区域有更大的毛状的密度控制心。统计分析在左室的喷射部分,心肌的表演索引,结束心脏舒张的压力,和山峰 +dP/dt 揭示了重要改进,在相对控制心的二组植入 ADSC 的心。有的更高的山峰 -dP/dt 比确实控制珍视的植入 AASC 的心,更高的喷射部分和山峰 +dP/dtvalues 比移植进心肌的疤织物的植入 UASC 的 hearts.Conclusions ADSC 形成了心脏的岛和像容器的结构,导致了 angiogenesis 并且改善心脏的功能。在培植前的 5-Azacytidine 预告的处理为扩充 myogenesis 是合乎需要的。进心肌的疤的 5-azacytidine-treated ADSC 的移植是比在心脏的功能的保藏的未经治疗的 ADSC 的更有效的。ZHANG Duan-zhen GAI Lu-yue LIU Hong-wei JIN Qin-hua HUANG Jian-hua ZHU Xian-yang 2007Chinese Medical Journal2007,,4:18
11Retrospective epidemiological study of thyroid nodules by ultrasound in asymptomatic subjects显示文摘Sharen Gaowa Zhang Bo Zhao Ruina Sun Jie Gai Xiaorong Lou Huiping 2014Chinese Medical Journal2014,,9:17
12Transposable elements play an important role during cotton genome evolution and fiber cell development显示文摘Transposable elements(TEs)usually occupy largest fractions of plant genome and are also the most variable part of the structure.Although traditionally it is hallmarked as'junk and selfish DNA',today more and more evidence points out TE’s participation in gene regulations including gene mutation,duplication,movement and novel gene creation via genetic and epigenetic mechanisms.The recently sequenced genomes of diploid cottons Gossypium arboreum(AA)and Gossypium raimondii(DD)together with their allotetraploid progeny Gossypium hirsutum(At At Dt Dt)provides a unique opportunity to compare genome variations in the Gossypium genus and to analyze the functions of TEs during its evolution.TEs accounted for 57%,68.5%and67.2%,respectively in DD,AA and At At Dt Dt genomes.The 1,694 Mb A-genome was found to harbor more LTR(long terminal repeat)-type retrotransposons that made cardinal contributions to the twofold increase in its genome size after evolution from the 775.2 Mb D-genome.Although the 2,173 Mb At At Dt Dt genome showed similar TE content to the A-genome,the total numbers of LTR-gypsy and LTR-copia type TEs varied significantly between these two genomes.Considering their roles on rewiring gene regulatory networks,we believe that TEs may somehow be involved in cotton fiber cell development.Indeed,the insertion or deletion of different TEs in the upstream region of two important transcription factor genes in At or Dt subgenomes resulted in qualitative differences in target gene expression.We suggest that our findings may open a window for improving cotton agronomic traits by editing TE activities.Kun Wang Gai Huang Yuxian Zhu 2016Science China(Life Sciences)2016,59,2:15
13Four-year clinical outcome in asymptomatic patients undergoing coronary computed tomography angiography显示文摘ZHANG Kai-yi GAI Lu-yue GAI Jing-jing HE Bin GUAN Zhi-wei 2013Chinese Medical Journal2013,,9:14
14Association of KIR Genotypes and Haplotypes with Susceptibility to Chronic Hepatitis B Virus Infection in Chinese Han Population显示文摘Killer immunoglobulin-like receptor (KIR) genes can regulate the activation of NK and T cells upon interaction with HLA class I molecules. Hepatitis B virus (HBV) infection has been regarded as a multi-factorial disorder disease. Previous studies revealed that KIRs were involved in HCV and HIV infection or clearance. The aim of this study was to explore the possibility of the inheritance of KIR genotypes and haplotypes as a candidate for susceptibility to persistent HBV infection or HBV clearance. The sequence specific primer polymerase chain reaction (SSP-PCR) was employed to identify the KIR genes and pseudogenes in 150 chronic hepatitis B (CHB) patients, 251 spontaneously recovered (SR) controls, and 412 healthy controls. The frequencies of genotype G, M, FZ1 increased in CHB patients compared with healthy control subjects. The frequency of genotype AH was higher in SR controls than that in both CHB patients and healthy controls. The carriage frequencies of genotype G and AH were higher; while, the frequencies of AF and AJ were lower in SR controls than those in healthy control subjects. The frequency of A haplotype was lower, whereas, the frequency of B haplotype was higher in CHB patients and SR controls than those in healthy controls. In healthy controls, haplotype 4 was found lower compared with that in CHB patients and SR controls and the frequency of haplotype 5 was higher in SR controls than that in other two groups. Based on these findings, it seems that the genotypes M and FZ1 are HBV susceptive genotypes; AH, on the other hand, may be protective genotypes that facilitate the clearance of HBV. It appears that the haplotype 4 is HBV susceptive haplotype, whereas, haplotype 5 may be the protective haplotype that facilitates the clearance of HBV.Zhiming Lu Bingchang Zhang Shijun Chen Zhongtao Gai Zhaolei Feng Xiangdong Liu Yiqing Liu Xin Wen Li Li Yulian Jiao Chunyan Ma Song Shao Xiangfa Cui Guojian Chen Jianfeng Li Yneran Zhao 2008Cellular & Molecular Immunology2008,5,6:13
15Identification, Genetic Analysis and Mapping of Resistance to Phytophthora sojae of Pm28 in Soybean显示文摘Phytophthora sojae Kanfman and Gerdemann (P. sojae) is one of the most prevalent pathogens and causes Phytophthora root rot, which limits soybean production worldwide. Development of resistant cultivars is a cost-effective approach to controlling this disease. In this study, 127 soybean germplasm were evaluated for their responses to Phytophthora sojae strain Pm28 using the hypocotyl inoculation technique, and 49 were found resistant to the strain. The hypocotyl of P1, P2, F1, and F2:3 of two crosses of Ludou 4 (resistant)×Youchu 4 (susceptible) and Cangdou 5 (resistant)×Williams (susceptible) were inoculated with Pm28, and were used to analyze the inheritance of resistance. The population derived from the cross of Ludou 4×Youchu 4 was used to map the resistance gene (designated as Rps9) to a linkage group. 932 pairs of SSR primers were used to detect polymorphism, and seven SSR markers were mapped near the resistance gene. The results showed that the resistance to Pm28 in Ludou 4 and Cangdou 5 was controlled by a single dominant gene Rps9, which was located on the molecular linkage group N between the SSR markers Satt631 (7.5 cM) and Sat_186 (4.3 cM).WU Xiao-ling ZHANG Bao-qiang SUN Shi ZHAO Jin-ming YANG Feng GUO Na GAI Jun-yi XING Han 2011Agricultural Sciences in China2011,10,10:13
16Ovarian Damages Produced by Aerosolized Fine Particulate Matter (PM2.5) Pollution in Mice: Possible Protective Medications and Mechanisms显示文摘Hui-Fang Gai Jian-Xiong An Xiao-Yan Qian Yong-Jie Wei John P Williams Guo-Lan Gao 2017Chinese Medical Journal2017,,12:13
17mTOR/miR-145-regulated exosomal GOLM1 promotes hepatocellular carcinoma through augmented GSK-3b/MMPs显示文摘Golgi membrane protein 1(GOLM1/GP73)is a serum marker of hepatocellular carcinoma(HCC).We have previously shown that mTOR promoted tumorigenesis of HCC through stimulating GOLM1 expression.In this study,we demonstrated that the mammalian target of rapamycin(mTOR)was a negative regulator of microRNA-145(miR-145)expression.miR-145 inhibited GOLM1 expression by targeting a coding sequence of GOLM1 gene.GOLM1 and miR-145 were inversely correlated in human HCC tissues.GOLM1-enriched exosomes activated the glycogen synthase kinase-3β/matrix metalloproteinases(GSK-3β/MMPs)signaling axis of recipient cells and accelerated cell proliferation and migration.In contrast,miR-145 suppressed tumorigenesis and metastasis.We suggest that mTOR/miR-145/GOLM1 signaling pathway should be targeted for HCC treatment.Xiaochen Gai Bufu Tang Fangming Liu Yuting Wu Fang Wang Yanling Jing Fuqiang Huang Di Jin Ling Wang Hongbing Zhang 2019Journal of Genetics and Genomics2019,46,5:13
18Comparison of symptom and risk assessment methods among patients with chronic obstructive pulmonary disease显示文摘Zhang Rongbao Tan Xingyu He Quanying Chen Qing Gai Jun Wei Jing'an Wang Yan 2014Chinese Medical Journal2014,,14:12
19Nutritional effects of the dietary inclusion of partially defatted Hermetia illucens larva meal in Muscovy duck显示文摘Background: The present work is aimed at evaluating the effect of different inclusion levels of a partially defatted black soldier fly(Hermetia illucens,L.;HI) larva meal for ducks.A total of 192 female 3-day-old Muscovy ducklings(Cairina moschata domestica,Canedins R71 L White,Grimaud Freres Selection,France) were divided into 4 groups,assigned 4 different dietary treatments(6 replicates/treatment and 8 birds/replicate) and reared from 3 to 50 days of age.HI larva meal was included at increasing levels(0,3%,6% and 9%,HI0,HI3,HI6 and HI9,respectively) in isonitrogenous and isoenergetic diets formulated for 3 feeding phases: starter(3–17 days of age),grower(18–38 days of age) and finisher(39–50 days of age).The growth performance and apparent total tract digestibility were evaluated during the trial using titanium dioxide as an inert marker(0.3% of inclusion).At 51 days of age,two birds per pen were slaughtered and histomorphological investigations were performed.Results: The live weight and average daily gain showed a quadratic response to increasing HI meal in the grower period(minimum corresponding to the HI6 group).No effects of dietary inclusion levels were observed for the daily feed intake or feed conversion ratio.The apparent dry matter and organic matter digestibility were not affected by the dietary treatment.A linear decrease was observed for the crude protein apparent digestibility in the starter period(minimum for the HI9 groups).The ether extract apparent digestibility increased linearly during the grower and finisher periods(minimum for the HI0 group).The morphometric indices were not influenced by the dietary treatments.Conclusions: The inclusion of up to 9% of HI partially defatted larva meal in the diet of ducks did not cause any effect on growth performance,as well as the apparent digestibility.Moreover,dietary HI inclusion preserved the physiological intestinal development.Marta Gariglio Sihem Dabbou Ilaria Biasato Maria Teresa Capucchio Elena Colombino Fuensanta Hernandez Josefa Madrid Silvia Martinez Francesco Gai Christian Caimi Sara Bellezza Oddon Marco Meneguz Angela Trocino Riccardo Vincenzi Laura Gasco Achille Schiavone 2019Journal of Animal Science and Biotechnology2019,10,3:12
20Echinacoside induces rat pulmonary artery vasorelaxation by opening the NO-cGMP-PKG-BKca channels and reducing intracellular Ca2+ levels显示文摘Xiang-yun GAI Yu-hai WEI Wei ZHANG Ta-na WUREN Ya-ping WANG Zhan-qiang LI Shou LIU Lan MA Dian-xiang LU Yi ZHOU Ri-li GE 2015Acta Pharmacologica Sinica2015,36,5:11
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