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| 1 | Research advances on the multiple uses of Moringa oleifera: a sustainable alternative for socially neglected population显示文摘Moringa oleifera Lam(Moringaceae) is a plant with high nutritional and medicinal value. Native to India, it is now widely distributed throughout tropical and subtropical regions of the world. Its different parts are sources of proteins, vitamins and minerals and present different pharmacological and biotechnological potential. Moreover, M. oleifera seeds are widely used in water and effluent treatment, for their coagulation, flocculation and sedimentation properties, their ability of improving water quality, by reducing organic matter and microbial load, with special applicability in intensive animal production systems, such as aquaculture. In addition, due to its high nutritional value and several medicinal properties, this tree may act as a nutritional and medical alternative for socially neglected populations. In this context, this review gathers information on M. oleifera, emphasizing its chemical constituents, nutritional, pharmacological and antimicrobial properties, applications in the treatment of water effluents, and ecological and social aspects. | Raimunda Samia Nogueira Brilhante Jamille Alencar Sales Vandbergue Santos Pereira Débora de Souza Collares Maia Castelo-Branco Rossana de Aguiar Cordeiro Célia Maria de Souza Sampaio Manoel de Araújo Neto Paiva Joao Bosco Feitosa dos Santos JoséJúlio CostaSidrim Marcos Fábio Gadelha Rocha | 2017 | Asian Pacific Journal of Tropical Medicine2017，10，7： | 10 |
| 2 | Occlusion of the anterior cerebral artery after head trauma显示文摘Intracranial arterial occlusion is rarely encountered in association with head injury.Only six cases of traumatic occlusion of the anterior cerebral artery(ACA) have previously been reported.In this paper,the authors describe a case of a posttraumatic occlusion of ACA.A 35-year-old male presented to the emergency room with severe head injury.Computed tomography(CT) scan displayed diffuse brain swelling with multiple skull fractures.Follow up CT scan showed extensive cerebral infarction in the territory of ACA.The patient underwent CT angiography that demonstrated occlusion of the ACA by a fracture of the anterior fossa.He died after 3 d.ACA traumatic occlusion is a rare condition,with poor prognosis.In this case,fracture was responsible for dissection and direct obstruction of the artery. | Wellingson Silva Paiva Almir Ferreira de Andrade Matheus Schmidt Soares Robson Luis Amorim Eberval Gadelha Figueiredo Manoel Jacobsen Teixeira | 2013 | World Journal of Radiology2013，5，5： | 7 |
| 3 | Characterization of goat whey proteins and their bioactivity and toxicity assay显示文摘Goat whey is an industry-discarded dairy by-product that has interesting nutritional value and a nutrient composition with important functional potential,where proteins have a high biological value and play an important role in the organism’s physiology.Therefore,the aim of this study was to identify,quantify,concentrate and investigate the capacity of goat whey proteins to perform different biological activities and to evaluate their acute toxicity.Concentrated proteins were quantified and identified by Bradford,Kjehdal and SDS-PAGE methods.Antibacterial activity was performed against Listeria monocytogenes,Salmonella spp.,Staphylococcus aureus,Pseudomonas aeruginosa and Escherichia coli microorganisms and showed MIC ranging from 15 to 120μg mL-1,with the highest inhibition for L.monocytogenes growth.Antiproliferative activity was performed against human malignant melanoma cells and their proliferation inhibition was up to 66.8%within 72 h of exposure.The highest antioxidant capacity was obtained at concentration 2 mg that showed 29.69%of inhibition of DPPH radical oxidation.The acute toxicity test was performed using Artemia franciscana larvae in which whey proteins were able to preserve larval survival throughout exposure.Thus,we can conclude that goat’s whey has proteins that can play a positive effect on health,with antimicrobial activity and without toxicity.The present study highlights the great potential of goat’s whey to be developed as a safe biopreservative or as a functional ingredient in the food industry. | Maria Isabel Ferreira Campos Paula Perazzo de Souza Barbosa Laura Junqueira Camargo Luciano Da Silva Pinto Bianca Mataribu Catarina Serr˜ao Luis Fernando Marques-Santos Jos´e Hon´orio Lopes Julia Mariano Caju de Oliveira Carlos Alberto de Almeida Gadelha Tatiane Santi-Gadelha | 2022 | Food Bioscience2022，46，2： | 2 |
| 4 | Correlation of p53 status with outcome of neoadjuvant chemotherapy using paclitaxel and doxorubicin in stage ⅢB breast cancer显示文摘 | Anelli A Brentani R R Gadelha A P | 2003 | Ann Oncol2003，14，3： | 1 |
| 5 | Prevalence of the metabolic syndrome and its components in Brazilian women with polycystic ovary syndrome显示文摘 | Soares EMM Azevedo GD Gadelha RGN | 2008 | Fertil Steril2008，89，3： | 1 |
| 6 | Prevalence of the metabolic syndrome and its components in Brazil- ian women with polycystic ovary syndrom显示文摘 | Som'es EM Azevedo GD Gadelha RG | 2008 | Fertil Steril2008，89，： | 1 |
| 7 | Discovery of novel inter- mediate forms redefines the fungal tree of life 显示文摘 | Jones M D M Forn I Gadelha C | 2011 | Nature2011，474，7350： | 1 |
| 8 | Quantification and comparison of telovelar and transvermian approaches to the fourth ventricle 显示文摘 | Vivek R Deshmukh E Gadelha F | 2006 | Neurosurgery2006，58，2： | 1 |
| 9 | The evaluation of a semiautomated computer method to determine the effects of DMSO on Giardia lamblia-intestinal cell interaction显示文摘 | Gadelha AP Travassos R Monteiro-Leal LH | 2007 | Parasitol Res2007，101，5： | 1 |
| 10 | Correlation of p53status with outcome of neoadjuvant chemotherapy using paclitaxel and doxorubicin in stage ⅢB breast cancer 显示文摘 | Anelli A Brentani RR Gadelha AP | 2003 | Ann Oncol2003，14，3： | 1 |
| 11 | Prevalence of the metabolic syndrome and its components in Brazilian women with polycystic ovary syndrome显示文摘 | Soares EMM Azevedo GD Gadelha RGN | 2008 | Fertil Steril2008，89，3： | 1 |
| 12 | Role of the NO/cGMP/K (ATP) pathway in the protective effects of sildenafil against ethanol- induced gastric damage in rats显示文摘 | Medeiros JV Gadelha GG Lima SJ | 2008 | Br J Pharmaeol2008，153，4： | 1 |
| 13 | A novel role for BRCA1 in regulating breast cancer cell spreading and motility显示文摘 | Coene ED Gadelha C White N | 2011 | J Cell Biol2011，192，11： | 1 |
| 14 | Peripheral interleu-kin- 2 level is associated with negative symptoms and cogni-tive performance in schizophrenia显示文摘 | Asevedo E Rizzo LB Gadelha A | 2014 | Physiol Behav2014，129，： | 1 |
| 15 | JAK2V617 F mutation in patients with splanchnic vein thrombosis 显示文摘 | Xavier SG Gadelha T Pimenta G | 2010 | Dig Dis Sci2010，55，6： | 1 |
| 16 | Correlation of p53 status with outcome of neoadjuvant chemotherapy using paclitaxel and doxorubicin in stage Ⅲ B breast cancer 显示文摘 | Anelli A Brentani RR Gadelha AP | 2003 | Ann Oncol2003，14，3： | 1 |
| 17 | Correlation ofp53 status with outcome of neoadjuvant chemotherapy usingpaciitaxel and doxorubicin in stage ffl B breast cancer 显示文摘 | A Anelli RR Brentani? AP Gadelha | 2003 | Ann Oncol ’2003，14，： | 1 |
| 18 | Clinical significance of a negative D-dimer level in patients with confirmed venous thromboembolism, findings from the RIETE registry显示文摘 | Soto MJ Grau E Gadelha T | 2011 | J Thromb Haemost2011，9，2： | 1 |
| 19 | The growth hormone(GH)-axis of GH receptor/binding protein gene-desrupted and metallothionein-human GH-releasing hormone transgenic mice:Hypothalamic neuropeptide and pituitary receptor expression in the absence and presence of GH feedback显示文摘 | PENG X D PAKR S GADELHA M R | 2001 | Endocrinology2001，142，3： | 1 |
| 20 | Circulating levels of sTNFR1 as a marker of severe clinical course in schiz- ophrenia显示文摘 | NOTO C GADELHA A BELANGERO SI | 2013 | J Psychiatr Res2013，47，4： | 1 |
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