维普中文期刊产品整合服务
24篇 您的检索式:作者名="G Pottle"
    题名 作者 年代 出处 被引量
1Calcium signaling and T-type calcium channels in cancer cell cycling显示文摘Regulation of intracellular calcium is an important signaling mechanism for cell proliferation in both normal and cancerous cells. In normal epithelial cells, free calcium concentration is essential for cells to enter and accomplish the S phase and the M phase of the cell cycle. In contrast, cancerous cells can pass these phases of the cell cycle with much lower cytoplasmic free calcium concentrations, indicating an alternative mechanism has developed for fulfilling the intracellular calcium requirement for an increased rate of DNA synthesis and mitosis of fast replicating cancerous cells. The detailed mechanism underlying the altered calcium loading pathway remains unclear; however, there is a growing body of evidence that suggests the T-type Ca2+ channel is abnormally expressed in cancerous cells and that blockade of these channels may reduce cell proliferation in addition to inducing apoptosis. Recent studies also show that the expression of T-type Ca2+ channels in breast cancer cells is proliferation state dependent, i.e. the channels are expressed at higher levels during the fast-replication period, and once the cells are in a non-proliferation state, expression of this channel isminimal. Therefore, selectively blocking calcium entry into cancerous cells may be a valuable approach for preventing tumor growth. Since T-type Ca2+ channels are not expressed in epithelial cells, selective T-type Ca2+ channel blockers may be useful in the treatment of certain types of cancers.James T Taylor Xiang-Bin Zeng Jonathan E Pottle Kevin Lee Alun R Wang Stephenie G Yi lennifer A S Scruggs Suresh S Sikka Ming Li 2008World Journal of Gastroenterology2008,14,32:12
2Wireless integrated network sensors显示文摘Pottle G J Kaiser W J 2000Communications of the ACM2000,43,5:1
3Wireless integrated network sensors显示文摘Pottle G J Kaiser WJ 2004Communications of the ACM2004,43,5:1
4Wireless integrated network sensors显示文摘Pottle G J Kaiser W J 2000Communications of the ACM2000,43,5:1
5Wireless integrated network sensors显示文摘Pottle G J Kaiser W J 2000Communications of the ACM2000,43,5:1
6Wireless Integrated Network Sen- sors显示文摘POTTLE G KAISER W 2000Communications of the ACM2000,43,5:1
7Wireless sensor networks显示文摘Pottle G Kaiser W 2000Communications of the Association for Computing Machinery2000,43,5:1
8Wireless integrated network sensors显示文摘POTTLE G J KAISER W J 2000Commun ACM2000,43,5:1
9Integrated Low-Power Communication System Design for Wireless Sensor Networks 显示文摘Lin T-H Kaiser W J Pottle G J 2004IEEE Communications Magazine2004,42,12:1
10Wireless integrated network sensors显示文摘Pottle G J Kaiser W J 2000Communications of the ACM2000,43,5:1
11Wireless sensor networks显示文摘Pottle G Kaiser W 2000Commu-nications of the ACM2000,43,5:1
12Wireless integrated network sensors 显示文摘Pottle G Kaiser W 2000Comm ACM2000,43,5:1
13Wireless integrated network sensors 显示文摘POTTLE G J KAISER W J 2000Communications of the ACM2000,43,5:1
14Wireless integrated network sensors 显示文摘POTTLE G J KAISER W J 2000Communications of theACM2000,3,5:1
15Instrumenting the world with wireless sensor networks 显示文摘D Estrin L Girod G Pottle M Srivastava 2001ICASSP Salt Lake City UT2001,2001,:1
16Wireless integrated network sensors 显示文摘Pottle G Kaiser W 2000Communications of ACM2000,43,5:1
17Wireless integrated network sensors显示文摘Pottle G J Kaiser W J 2000Communications of the ACM2000,43,5:1
18Operational characteristics of a Lager wind-farm utility-system with a controllable ac/dc/ac inverter显示文摘 Arun G Phadke Christopher pottle 1988IEEE Transactions on Power Systems1988,3,1:1
19Integrated low-power communication system design for wireless sensor networks 显示文摘Lin Tsung-hsien Kaiser W J Pottle G J 2004Communications Magazine IEEE2004,42,12:1
20Wireless integrated newtork sensors显示文摘Pottle G J Kaiser W J 2000Communications of the ACM2000,43,5:1
返回顶部 每页显示:
共2页 首页 上一页 第1页 下一页 末页 /2 跳转

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1 渝公网安备 50019002500403号 违法和不良信息举报中心

互联网出版许可证 新出网证(渝)字10号 全国400电话 - 免长途话费