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| 1 | Challenge of liver disease in systemic lupus erythematosus:Clues for diagnosis and hints for pathogenesis显示文摘Systemic lupus erythematosus(SLE) encompass a broad spectrum of liver diseases. We propose here to classify them as follows:(1) immunological comorbilities(overlap syndromes);(2) non-immunological comorbilities associated to SLE; and(3) a putative liver damage induced by SLE itself, referred to as 'lupus hepatitis'. In the first group, liver injury can be ascribed to overlapping hepatopathies triggered by autoimmune mechanisms other than SLE occurring with higher incidence in the context of lupus(e.g., autoimmune hepatitis, primary biliary cirrhosis). The second group includes non-autoimmune liver diseases, such as esteatosis, hepatitis C, hypercoagulation state-related liver lesions, hyperplasic parenchymal and vascular lesions, porphyria cutanea tarda, and drug-induced hepatotoxicity. Finally, the data in the literature to support the existence of a hepatic disease produced by SLE itself, or the occurrence of a SLE-associated prone condition that increases susceptibility to acquire other liver diseases, is critically discussed. The pathological mechanisms underlying each of these liver disorders are also reviewed. Despite the high heterogeneity in the literature regarding the prevalence of SLE-associated liver diseases and, in most cases, lack of histopathological evidence or clinical studies large enough to support their existence, it is becoming increasingly apparent that liver is an important target of SLE. Consequently, biochemical liver tests should be routinely carried out in SLE patients to discard liver disorders, particularly in those patients chronically exposed to potentially hepatotoxic drugs. Diagnosing liver disease in SLE patients is always challenging, and the systematization of the current information carried out in this review is expected to be of help both to attain a better understanding of pathogenesis and to build an appropriate work-up for diagnosis. | Ferno Bessone Natalia Poles Marcelo G Roma | 2014 | World Journal of Hepatology2014，6，6： | 7 |
| 2 | A mechanism for transition-metal nanoparticle self-assembly显示文摘 | Besson C Finney E E Finke R G | 2005 | J Am Chem Soc2005，127，22： | 1 |
| 3 | Knowledge-aided covariance matrix estimation and adaptive detection in compound-Gaussian noise显示文摘 | Bandiera F Besson O and Ricci G | 2010 | IEEE Transactions on Signal Processing2010，58，10： | 1 |
| 4 | Structure de la bacillomycine L, antibiotique de Bacillus subtilis显示文摘 | Besson F Peypoux F Michel G | 1977 | Europ Biochem1977，77，： | 1 |
| 5 | Characterisation of iturin A in antibiotics from various strains of Bacillus subtilis显示文摘 | Besson F Peypoux F Michel G | 1976 | J Antibiot1976，29，10： | 1 |
| 6 | Action of the antibiotics of the iturin group on artificial membranes显示文摘 | Besson F Michel G | 1984 | J Antibiot(Tokyo)1984，37，6： | 1 |
| 7 | Identification and developmental expression of a Bombyx mori α-tubulin gene显示文摘 | Hachouf-Gherras S Besson M T Bosquet G | 1998 | Gene1998，208，： | 1 |
| 8 | Catalytic wet-air oxidation of industrial effluents: Total mineralization of organics and lumped kinetic modelling显示文摘 | Pintar A Bercic G Besson M | 2004 | Appl Catal B2004，47，3： | 1 |
| 9 | Effects of the analgesic agent tramadol in normal and arthritic rats:comparison with the effects of different opioids,including tolerance and cross-tolerance to morphine显示文摘 | Kayser V Besson JM Guildbaud G | 1991 | Euopean Journal of Pharmacology1991，195，： | 1 |
| 10 | Pitting of aluminium in non-aqueous chloride media显示文摘 | Bessone J B | 1999 | Corrosion Science1999，41，： | 1 |
| 11 | Catalytic Wet-Air oxidation of Indust rial Effluent s: Total Mineralizationof Organics and Lumped Kinetic Modelling显示文摘 | PINTAR A BERCIC G BESSON M | 2004 | Appl Catal2004，47，3： | 1 |
| 12 | Isolation and characterization of new i- turins: iturin D and iturin E显示文摘 | BESSON F MICHEL G | 1987 | Journal of Antibiotics1987，40，： | 1 |
| 13 | Increased risk for cervicaldisease progression of French women infected with the human pap-illomavirus type 16 E6350G variant 显示文摘 | Grodzki M Besson G Clavel C | 2006 | Cancer Epidemiol Biomark-ers Prev2006，15，6： | 1 |
| 14 | Neurological aspects of Fabry's disease显示文摘 | Clavelou P Besson G Elziere C | 2006 | Rev Neurol(Paris)2006，162，5： | 1 |
| 15 | Increased Risk for Cervical Disease Progression of French Women Infected with the Human Papillomavirus Type 16E6 -350G Variant 显示文摘 | Grodzki M Besson G Clavel C | 2006 | Cancer Epidem Biomar2006，15，4： | 1 |
| 16 | Influence of alloying elements and microstructure on aluminum sacrificial anode performance:Case of Al-Zn显示文摘 | Salinas D R Garcia S G Bessone J B | 1999 | Journal of Applied Electrochemistry1999，29，9： | 1 |
| 17 | CT image reconstruction from fan-parallel data 显示文摘 | G Besson | 1999 | Med Phys1999，26，： | 1 |
| 18 | Early clinical diagnosis of stroke subtypes显示文摘 | Bogousslavsky J Regli F Besson G | 1993 | Cerebrovasc Dis1993，3，： | 1 |
| 19 | 查看详情显示文摘 | Klotz S Besson J M Hamel G Nelmes R J Loveday J S Mar-shallW G Wilson R M | | 0，，： | 1 |
| 20 | CT image reconstruction from fan-parallel data显示文摘 | Besson G | 1999 | Medical Physics1999，26，： | 1 |
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