| 1 | Vapor-Phase Precise-Synthesis of 2D Inorganic Materials for Optoelectronics显示文摘Comprehensive Summary 2D materials have attracted intensive attention due to their unique electrical and optical properties associated with their strictly defined low dimensionalities.They provide a wide range of basic building blocks for future electronics and optoelectronics.The chemical vapor deposition(CVD)has been proposed to be efficient to realize the controllable thickness,scalable size,which are necessary for both industrial applications and fundamental researches.Herein,we share our research works to realize the controllable growth of 2D materials.We found that stable growth microenvironment can regulate the growth of 2D materials.Thus,we developed near-steady source supply,space-confined,and additive-assisted passivated growth methods to solve the problem of unstable growth environment caused by uneven source and mass transfer.Then,we developed several strategies to precisely control the parity,separation,and transport of the carriers in 2D materials including fabricating defect-free interface via van der Waals dielectrics,modulating the parity of carriers via ferroelectric-field,and the separation of carriers via band engineering.Toward future development,we highlight the opportunities and challenges inthis field. | Xing Zhou Fuwei Zhuge Han Wang Tianyou Zhai | 2023 | Chinese Journal of Chemistry2023，41，7： | 0 |
| 2 | Discharge heart rate and 1-year clinical outcomes in heart failure patients with atrial fibrillation显示文摘Background: The association between heart rate and 1-year clinical outcomes in heart failure (HF) patients with atrial fibrillation (AF), and whether this association depends on left ventricular ejection fraction (LVEF), are unclear. We investigated the relationship between discharge heart rate and 1-year clinical outcomes after discharge among hospitalized HF patients with AF, and further explored this association that differ by LVEF level.Methods: In this analysis, we enrolled 1760 hospitalized HF patients with AF from the China Patient-centered Evaluative Assessment of Cardiac Events Prospective Heart Failure study from August 2016 to May 2018. Patients were categorized into three groups with low (<65 beats per minute [bpm]), moderate (65-85 bpm), and high (≥86 bpm) heart rate measured at discharge.Cox proportional hazard models were employed to explore the association between heart rate and 1-year primary outcome, which was defined as a composite outcome of all-cause death and HF rehospitalization.Results: Among 1760 patients, 723 (41.1%) were women, the median age was 69 (interquartile range [IQR]: 60-77) years, median discharge heart rate was 75 (IQR: 69-84) bpm, and 934 (53.1%) had an LVEF <50%. During 1-year follow-up, a total of 792 (45.0%) individuals died or had at least one HF hospitalization. After adjusting for demographic characteristics, smoking status, medical history, anthropometric characteristics, and medications used at discharge, the groups with low (hazard ratio [HR]: 1.32, 95% confidence interval [CI]: 1.05-1.68,P = 0.020) and high (HR: 1.34, 95% CI: 1.07-1.67,P = 0.009) heart rate were associated with a higher risk of 1-year primary outcome compared with the moderate group. A significant interaction between discharge heart rate and LVEF for the primary outcome was observed (P for interaction was 0.045). Among the patients with LVEF ≥50%, only those with high heart rate were associated with a higher risk of primary outcome compared with the group with moderate heart rate (HR: 1.38, 95% CI: 1.01-1.89,P = 0.046), whereas there was no difference between the groups with low and moderate heart rate. Among the patients with LVEF <50%, only those with low heart rate were associated with a higher risk of primary outcome compared with the group with moderate heart rate (HR: 1.46, 95% CI: 1.09-1.96,P = 0.012), whereas there was no difference between the groups with high and moderate heart rate.Conclusions: Among the overall HF patients with AF, both low (<65 bpm) and high (≥86 bpm) heart rates were associated with poorer outcomes as compared with moderate (65-85 bpm) heart rate. Among patients with LVEF ≥50%, only a high heart rate was associated with higher risk;while among those with LVEF <50%, only a low heart rate was associated with higher risk as compared with the group with moderate heart rate.Trail Registration: Clinicaltrials.gov;NCT02878811. | Fuwei Xing Xin Zheng Lihua Zhang Shuang Hu Xueke Bai Danli Hu Bing Li Jing Li | 2022 | Chinese Medical Journal2022，，1： | 0 |
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