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| 1 | Environmental magnetic studies of lacustrine sediments显示文摘In recent decades, environmental magnetism has become an important method for studying past global climatic and environmental changes. For an environmental magnetic study, it is important to understand the magnetic properties of various magnetic minerals in lacustrine sediments and the processes involved in the formation, transport, and preservation of these magnetic minerals. The magnetic response of lacustrine sediments to climatic change may vary widely from lake to lake. To reconstruct the processes contributing to paleoclimatic and paleoenvironmental change, it is, therefore, necessary to derive a complete understanding of the potential origin of the magnetic signal observed. | HU Shouyun, DENG Chenglong, E. Appel & K. L. VerosubNanjing Institute of Geography and Limnology, Nanjing 210008, China Institute of Geology and Geophysics, Beijing 100101, China Institut fur Geologic, Universitat Tubingen, 72076 Tubingen, Germany Departm | 2002 | Chinese Science Bulletin2002，47，7： | 18 |
| 2 | SYNTHESIS OF INTERMETALLICS BY MECHANICAL ALLOYING显示文摘SYNTHESISOFINTERMETALLICSBYMECHANICALALLOYINGF.H.(Sam)Froes;C.Suryanarayana;andD.Mukhopadhyay(InstituteforMaterialsandAdvance... | F. H.(Sam) Froes C. Suryanarayana and D. Mukhopadhyay (Institute for Materials and Advanced Processes (IMAP), University of Idaho,Moscow, ID 83844-3026, USA)C-G. Li(BlM, P.O. Box 81 , Beijing, 100095, P.R. CHINA)K. Brand(On leave from Institut fur Werkst | 1995 | Acta Metallurgica Sinica(English Letters)1995，8，Z1： | 10 |
| 3 | Comparative Study on the Long-term Effect of Permanent Embolization of Hepatic Artery with Bletilla Striata in Patients with 显示文摘ComparativeStudyontheLong-termEffectofPermanentEmbolizationofHepaticArterywithBletillaStriatainPatientswithPrimaryLiverCancer... | FENG Gansheng Cramann B ZHENG Zhuansheng et al(Department of Radiology,Xiehe Hospital, Tongji Medical University,Wuhan 430030 Abteilung fur Radio-Diagnostik,Universitatsklinik,Homburg/Saar,Deutschland) | 1996 | Journal of Huazhong University of Science and Technology(Medical Sciences)1996，16，2： | 8 |
| 4 | Determination of Elastic and Creep Properties of Thin-film Systems from indentation Experiments显示文摘Based on the detailed computer .simulation of the indentation testing on the thin-film systems, the present paper explores the detailed procedure of determining elastic properties (elastic modulus E(f) and Poisson ratio v(f) ) and creep parameters (CCREEP (f) and nCREEP (f)) for a simple Norton law (ε=CCREEP (f)σnCREEP(f), where ε is creep strain rate, and σ is the stress) material for a thin film coated on a creep substrate, whose elastic properties(E(s) and v(s)) and creep properties (CCREEP(s) and nCREEP(s) ) of the substrate are known, from indentation elastic and creep testing, respectively. The influences of the thickness of the thin-film and the size of the indenter on the indentation behavior have been discussed. It is shown that the boundary between the thin film and the substrate has great influence on the indentation creep behavior. The relative sizes of indentation systems are chosen so that the behavior of the indentation on the film is influenced by the substrate. The two elastic parameters E(f) and v(f) of the film are coupled on the influence of the elastic behavior of indentation. With the two different size indenters, the two elastic parameters E(f) and v(f) of the film can be uniquely determined by the indentation experimental slopes of depth to applied net section stress results. The procedure of determining of the two Norton law parameters CCREEP (f) and nCREEP(f) includes the following steps by the steady indentation rate d. The first step to calculate the creep indentation rate on certain loads of the two different sizes of indenters on a set of assumed values of CCREEP (f) and nCREEP (f). Then to build relationship between the creep indentation rate and the assumed CCREEP(f) and nCREEP(f). With the experimental creep indentation rate to intersect two sets of CCREEP (f) and nCREEP(f), which have the same values of d. The last step is to build the CCREEP(f) and nCREEP(f)curves from the intersection points for the two indenters.These two curves CCREEP and nCREEP(f) will intersect at one point. The axial values of the point are what we want. The procedure presented in the paper to determine the elastic parameters and creep parameters from the indentation experiments can be applied to any material systems. | Z.F.Yue and G.Eggeler (Institut fur Werkstoffe, Ruhr-Universitat Bochum, 44 801 Bochum, Germany) | 2000 | Journal of Materials Science & Technology2000，16，6： | 8 |
| 5 | NaAlSi_3O_8-hollandite and other high-pressure minerals in the shock melt veins of the Suizhou meteorite显示文摘The Suizhou L6 chondrite contains a few very thin shock melt veins of 0.02-0.09 mm in width. In spite of small width of the veins, shock-induced high-pressure phases, such as coarse-grained NaAlSi3O8-hollandite, ringwoodite, majorite and fine-grained matrix majorite-pyropess have been discovered in these veins. NaAlSi3O8-hollandite, the high-pressure phase of plagioclase, in Suizhou shock veins occurs as a single phase mineral, no silicate glassy phase, such as albitic glass, was incorporated with it. The presence of above-mentioned high-pressure phases constrains the high pressure (up to 23-24 GPa) and high temperature (up to 1900-2000℃) regime in Suizhou shock veins, and indicates that the duration of high-pressure regime in the veins should be long enough (a few seconds) for phase transformation and crystallization of minerals under pressure. The discovery of the first natural single-phase crystalline NaAlSi3O8- holland-ite in Suizhou meteorite is of important significance in understanding the Earth’ | XIE Xiande, CHEN Ming, WANG Deqiang & El Goresy A.1.Guangzhou Institute of Geochemistry, Chinese Academy of Sciences, Guangzhou 510640, China 2. Max-Planck-Institute fur Chemie, 55128 Mainz, Germany | 2001 | Chinese Science Bulletin2001，46，13： | 8 |
| 6 | Dietary advanced glycation end-products aggravate non-alcoholic fatty liver disease显示文摘AIM To determine if manipulation of dietary advanced glycation end product(AGE), intake affects nonalcoholic fatty liver disease(NAFLD) progression and whether these effects are mediated via RAGE. METHODS Male C57Bl6 mice were fed a high fat, high fructose, high cholesterol(HFHC) diet for 33 wk and compared with animals on normal chow. A third group were given a HFHC diet that was high in AGEs. Another group was given a HFHC diet that was marinated in vinegar to prevent the formation of AGEs. In a second experiment, RAGE KO animals were fed a HFHC diet or a high AGE HFHC diet and compared with wildtype controls. Hepatic biochemistry, histology, picrosirius red morphometry and hepatic mR NA were determined. RESULTS Long-term consumption of the HFHC diet generated significant steatohepatitis and fibrosis after 33 wk. In this model, hepatic 4-hydroxynonenal content(a marker of chronic oxidative stress), hepatocyte ballooning, picrosirius red staining, α-smooth muscle actin and collagen type 1A gene expression were all significantly increased. Increasing the AGE content of the HFHC diet by baking further increased these markers of liver damage, but this was abrogated by pre-marination in acetic acid. In response to the HFHC diet, RAGE-/-animals developed NASH of similar severity to RAGE+/+ animals but were protected from the additional harmful effects of the high AGE containing diet. Studies in isolated Kupffer cells showed that AGEs increase cell proliferation and oxidative stress, providing a likely mechanism through which these compounds contribute to liver injury. CONCLUSION In the HFHC model of NAFLD, manipulation of dietary AGEs modulates liver injury, inflammation, and liver fibrosis via a RAGE dependent pathway. This suggests that pharmacological and dietary strategies targeting the AGE/RAGE pathway could slow the progression of NAFLD. | Christopher Leung Chandana B Herath Zhiyuan Jia Sof Andrikopoulos Bronwyn E Brown Michael J Davies Leni R Rivera John B Furness Josephine M Forbes Peter W Angus | 2016 | World Journal of Gastroenterology2016，22，35： | 7 |
| 7 | Glutathione Peroxidase Revisited—Simulation of the Catalytic Cycle by Computer-Assisted Molecular Modelling显示文摘Glutathione peroxidase, the first example of selenoproteins identified in mammals, was subjected to force field calculations and molecular dynamics in order to enable a clearer comprehension of enzymatic selenium catalysis. Starting from the established X-ray structure of bovine GPX, all kinetically defined intermediates and enzyme substrate complexes were modelled. The models thus obtained support the hypothesis that the essential steps of the catalysis are three distinct redox changes of the active site selenium which, in the ground state, presents itself at the surface of selenoperoxidases as the center of a characteristic triad built by selenocysteine, glutarnine and tryptophan. In GPX, four arginine residues and a lysine residue provide an electrostatic architecture which, in each reductive step, directs the donor substrate GSH towards the catalytic center in such a way that 1ts sulfhydryl group must react with the selenium moiety. To this end, different equally efficient modes of substrate binding appear possible. The models are consistent with substrate specificity data, kinetic pattern and other functional characteristics of the enzyme. Comparison of molecular models of GPX with those of other members of the GPX superfamily reveals that the cosubstrate binding mechanisrns are unique for the classical type of cytosolic glutathione peroxidases but cannot operate e. g. in plasma GPX and phospholipid hydroperoxide GPX. The structural differences between the selenoperoxidases, shown to be relevant to their specificities, are discussed in terms of functional diversification within the GPX | K. -D. AUMANN N. BEDORF R. BRIGELIUS-FLOHED D. SCHOMBURG AND L. FLOHE(Gesellschaft fur Biotechnologische Forschung mbH (GBF) Mascheroder Weg 1, D-38124 Braunschweig, Germany Deutsches Institut fur Ernahrungsforschung (DIfE) Arthur-Scheunert-Allee 114 | 1997 | Biomedical and Environmental Sciences1997，10，2： | 6 |
| 8 | IMPROVING EIGENVECTORS IN ARNOLDI'S METHOD显示文摘The Ritz vectors obtained by Arnoldi’s method may not be good approxima- tions and even may not converge even if the corresponding Ritz values do. In order to improve the quality of Ritz vectors and enhance the efficiency of Arnoldi type algorithms, we propose a strategy that uses Ritz values obtained from an m-dimensional Krylov subspace but chooses modified approximate eigenvectors in an (m + 1)-dimensional Krylov subspace. Residual norm of each new approximate eigenpair is minimal over the span of the Ritz vector and the (m+1)th basis vector, which is available when the m-step Arnoldi process is run. The resulting modi- fied m-step Arnoldi method is better than the standard m-step one in theory and cheaper than the standard (m + 1)-step one. Based on this strategy, we present a modified m-step restarted Arnoldi algorithm. Numerical examples show that the modified m-step restarted algorithm and its version with Chebyshev acceleration are often considerably more efficient than the standard (m+ 1)-step restarted ones. | Zhong-xiao Jia (Department of Applied Mathematics, Dalian University of Technology, Dalian 116024, China) Ludwig Elsner (Fakultat fur Mathematik, University Bielefeld, Postfach 100131, 33501 Bielefeld,Germany) | 2000 | Journal of Computational Mathematics2000，18，3： | 4 |
| 9 | High concentration of calcium ions in Golgi apparatus显示文摘The interphase NIH3T3 cells were vitally fluorescentstained with calcium indicator fluo-3 and Glogi probe C6NBD-ceramide, and then the single cells were examined by laser scanning confocal microscopy (LSCFM) for subcellular distributions of Ca2+ and the location of Golgi apparatus. In these cells, the intracellular Ca2+ were found to be highly concentrated in the Golgi apparatus. The changes of distribution of cytosolic high Ca2+ region and the Golgi apparatus coincided with the cell cycle phase.In calcium free medium, when the plasma membrane of the cells which had been loaded with fluo-3/AM were permeated by digitonin, the fluorescence of the Golgi region decreased far less than that of the cytosol. Our results indicated that the Glogi lumen retained significantly high concentration of free calcium. | XUE SHAOBAI M. RoBERT NICOUD JIE CUI D.J.ARNDT JOVIN(Depariment of Biology, Beijing Normal University, Beijing 100875, China)(Max-Planck-Institute fur Biophysikalische Chemie,Gottingen, Germany) | 1994 | Cell Research1994，4，1： | 3 |
| 10 | Raman Spectroscopic Study of Silicon Nanopowders显示文摘Vibrational properties of silicon nanopowders are discussed with reference to Raman spectroscopic measurements. The powders were produced in a low pressure rf plasma from the cluster induced agglomeration of positive ions formed during the dissociation of silane. Influence of thermal treatment and the crystallization phenomena of the powder were studied. Raman spectroscopic measurements reveal size quantization effects for the particles as well as the existence of partially ordered regions in the apparently amorphous primary particles. The crystalline and amorphous volume fraction in the material were calculated from the relative spectraI intensities. The results obtained in these experiments are consistent with the observations from recent high resolution transmission electron microscopy studies of these | S.M.Scholz J.Dutta and H.Hofmann(Lab. de Technologie des Poudres, Departement de Materiaux, Ecole Polytechnique Federale de Lausanne,1015 Lausanne, Switzerland)H.Hofmeister (Max-Planck-Institut fur Mikrostrukturphysik, Weinberg 2, D-06120 Halle, Germany) | 1997 | Journal of Materials Science & Technology1997，13，4： | 3 |
| 11 | Sensitive Monoclonal Antibody‐based Sandwich ELISA for the Detection of Porcine Skeletal Muscle in Meat and Feed Products显示文摘 | LihuaLiu Fur‐ChiChen Jodee LDorsey Yun‐Hwa PeggyHsieh | 2006 | Journal of Food Science2006，，1： | 2 |
| 12 | Effects of protein deprivation and re-feeding on P2X_2 receptors in enteric neurons显示文摘AIM:To investigate the effects of malnutrition and refeeding on the P2X2 receptor,nitric oxide synthase(NOS),calretinin,calbindin and choline acetyltransferase(ChAT) in neurons of the rat ileum.METHODS:We analyzed the co-localization,numbers and sizes of P2X2-expressing neurons in relation to NOS-immunoreactive(IR),calbindin-IR,ChAT-IR,and calretinin-IR neurons of the myenteric and submucosal plexus.The experimental groups consisted of:(1) rats maintained on normal feed throughout pregnancy until 42 d post-parturition(N);(2) rats deprived of protein throughout pregnancy and 42 d post-parturition(D);and(3) rats undernourished for 21 d post-parturition and then given a protein diet from days 22 to 42(DR).The myenteric and submucosal plexuses were evaluated by double labeling by immunohistochemical methods for P2X2 receptor,NOS,ChAT,calbindin and calretinin.RESULTS:We found similar P2X2 receptor immunoreactivity in the cytoplasm and surface membranes of myenteric and submucosal neurons from the N,D and DR groups.Double labeling of the myenteric plexus demonstrated that approximately 100% of NOS-IR,calbindin-IR,calretinin-IR and ChAT-IR neurons in all groups also expressed the P2X2 receptor.In the submucosal plexus,the calretinin-IR,ChAT-IR and calbindin-IR neurons were nearly all immunoreactive for the P2X2 receptor.In the myenteric plexus,there was a 19% increase in numbers per cm2 for P2X2 receptor-IR neurons,64% for NOS-IR,84% for calretinin-IR and 26% for ChAT-IR neurons in the D group.The spatial density of calbindin-IR neurons,however,did not differ among the three groups.The submucosal neuronal density increased for calbindin-IR,calretinin-IR and ChAT-IR neurons.The average size of neurons in the myenteric plexus neurons in the D group was less than that in the controls and,in the re-fed rats;there was a 34% reduction in size only for the calretinin-IR neurons.CONCLUSION:This work demonstrates that expression of the P2X2 receptor is present in inhibitory,intrinsic primary afferent,cholinergic secretomotor and vasomotor neurons.Undernutrition affected P2X2 receptor expression in the submucosal plexus,and neuronal and size.These changes were rescued in the re-fed rats. | Rúbia Misawa Priscila Azevedo Girotti Márcia Sanae Mizuno Edson Aparecido Liberti John Barton Furness Patricia Castelucci | 2010 | World Journal of Gastroenterology2010，16，29： | 2 |
| 13 | Influence of pesticides and alfalfa on soilbiological properties显示文摘Several biochemical parameters, such as respiration rate (RIP) , biomass - C oxygen demand , andATP reflecting microorganism biomass and activities were determined. All soil samples were incubated at22℃ , 14. 5 ℃ for 60, 192 and 480h, respectively. All th | Ma Ruixia Sun Sien(Research Center for Eco Environmental Sciences , Chinese Academy of Sciences . Beijing 100085 , China) R. Hantschel, F. Beese(GSF - Institut fur the ecologic, Ingolstter Landstraβe 1 , D-8042 Neuherberg, Germany) | 1995 | Journal of Environmental Sciences1995，7，2： | 2 |
| 14 | THE INTEGRAL OF THE INVERSE FUNCTION OF φ FOR AN ANALYTICAL SOLUTION TO THE COMPRESSION OF A THIN WORKPIECE显示文摘An analytical solution of the unit pressure on a thin workpiece under compression has been obtained by using the inverse function of φ to the integral integral from 0 to x φ dx. Its result is basically the same as the prevailing numerical formula integral from 0 to x φdx=∑√1-Δx1. However, the new integral is simpler and more convenient to use. | Zhao, Dewen Northeast University of Technology, Shenyang 110006, China Fang, Youkang Institute fur Angewandte Mathematik Albert-Ludwigs Universitat, Hemann-Henter Str 10 7800 Freihurg.1. Br. BRD, Germany | 1993 | 中国有色金属学会会刊:英文版1993，3，1： | 2 |
| 15 | The Balser plate with ligament sllture:A dependable method of stabilizing the acromiocla vicular joint显示文摘 | Klinik fur Unfallchirurgie Plastische | 2000 | Unfa Uchirurg2000，103，9： | 1 |
| 16 | The pharmacology of apoptosis 显示文摘 | KINLOCH R A TREHRNE J M FURNESS L M | 1999 | Trends in Pharmacological Sciences1999，20，： | 1 |
| 17 | miR--96 regulates the progression of differentiation in mammalian cochlear in- ner and outer hair cells显示文摘 | Kuhn S Johnson SL Furness DN | 2011 | Proc Natl Acad Sci USA2011，108，： | 1 |
| 18 | Peripheral benzodiazepine binding sites:effect of PK 11195,1-2-chlorophenyl-N -methyl-N -(1-methylpropyl) -3-isoquinolinecarboxamide显示文摘 | Le Fur G Perrier M I Vaucher N | 1983 | Life Sci1983，32，16： | 1 |
| 19 | The enteric nervous system and regulation of intestinal motility 显示文摘 | Kunze W A Furness J B | 1999 | Annu Rev Physiol1999，61，： | 1 |
| 20 | Role of fine-needle aspiration biopsy and frozen section in the management of papillary thyroid carcinoma subtypes 显示文摘 | Fur Bedard YC Rosen IB | 2004 | World J Surg2004，28，9： | 1 |
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