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| 1 | Post-operative computed tomography scan – reliable tool for quality assessment of complete mesocolic excision显示文摘BACKGROUND Quality control in colon cancer surgery is an ongoing debate ever since standardization proved to be highly efficient in improving survival in rectal cancer. Complete mesocolic excision(CME) is widely acclaimed as the new goldstandard in colon cancer resections, thus it is imperative to establish quality criteria of CME in order to make it easily understood and verified by surgeons worldwide. One simple and reproducible tool could be the measurement of arterial stumps postoperatively and a straightforward way to test its reliability is to test it in a comparative study between CME and non-CME surgery.AIM To validate arterial stump measurement as a surgical quality tool by comparing CME with conventional radical colectomies.METHODS This was a retrospective study, carried out on a prospective database. We collected data from two groups of patients, divided according to standard CME with D2 central vascular ligation(group A) and non-standardized surgery(group B). The two groups were compared with regard to the arterial stump length after right-and left-sided colectomies for colon cancer. The actual stump lengths of the ileocolic artery(ICA) and inferior mesenteric artery(IMA) were compared with their theoretical best D2 position of predicted ligation levels(D2 PLLs) for calculating the potential for improvement. Measurements on follow-up computed tomography scans were carried out by three observers. Pathological data were recorded(specimen length, lymph node yield) and correlated with stump length.RESULTS We analysed 58 colectomies. The stump lengths(mean ± SD) in group A were16.97 ± 4.77 mm for ICA and 31.70 ± 15.71 mm for IMA, whereas group B had 49.93 ± 20.29 mm for ICA and 67.24 ± 28.71 mm for IMA. Shorter lengths were obtained in group A, by a mean difference of 35.66 mm(χ~2 = 27.38, P < 0.001),which was significant for all types of colectomies. Except for a 5.85 ± 4.71 mm difference for right colectomies, all the ligations from group A significantly reached their potential height(0.26 ± 12.18 mm from D2 PLL; χ~2 = 0.005, P = 0.944).Apart from three left colectomies, group B failed to reach D2 PLL, by a mean difference of 32.14 ± 26.15 mm(χ~2 = 21.77, P < 0.001). The calculated improvement potentials were significantly shorter in group A than in group B, by a mean of 31.88 mm(χ~2= 22.13, P < 0.001). The large spread of results in group B showed that there is significant variability(P = 0.004) when compared to standard surgery. Significant correlations were found between stump length, specimen length and number of lymph nodes(P = 0.018 and P = 0.008 respectively). No statistical difference was found between observers' measurements(P = 0.866).CONCLUSION Arterial stump monitoring is a significant step in defining surgical quality, as longer stumps contain residual mesocolic tissue and correlate with major prognostic factors. | Cristian Livadaru Stefan Morarasu Tudor Cristian Frunza Florina A Ghitun Elena Florina Paiu-Spiridon Florina Sava Cristina Terinte Dan Ferariu Sorinel Lunca Gabriel Mihail Dimofte | 2019 | World Journal of Gastrointestinal Oncology2019,11,3: | 2 |
| 2 | Perineural invasion in head and neck eaneers-a review显示文摘 | Frunza A Slavescu D Lascar I | 2014 | J Med Life2014,7,2: | 1 |
| 3 | Advantages and Barriers of Formative Assessment in the Teaching-learning Activity显示文摘 | Frunza V | 2014 | Procedia-Social and Behavioral Sciences2014,,114: | 1 |
| 4 | Some aspects of energy distribution in rotary forming processes 显示文摘 | CANTA T FRUNZA 0 SABADUS 0 TINTELECAN C | 1998 | Journal of Materials Processing Technology1998,8081,: | 1 |
| 5 | Mobius transformations in infinite dimension显示文摘 | Frunza M | 1991 | Rev Roumaine Math Pures Appl1991,36,: | 1 |
| 6 | Friction-assisted pressing of PM components显示文摘 | CANTA T FRUNZA D | 2003 | Journal of Materials Processing Technology2003,,: | 1 |
| 7 | Predictive markers of response to neoadjuvant therapy in rectal cancer显示文摘 | Luis Joaquín García-Flórez Guillermo Gómez-álvarez Ana Madalina Frunza Luis Barneo-Serra Carmen Martínez-Alonso Manuel Florentino Fresno-Forcelledo | 2014 | Journal of Surgical Research2014,,: | 1 |
| 8 | Removal of reactive black 5 azo dye from aqueous solutions by catalytic oxidation using CuO/ Al2O3 and NiO/Al2O3显示文摘 | Bradu C Frunza L Mihalche N | 2010 | Applied Catalysis B:Environmental2010,96,34: | 1 |
| 9 | The embedding of chiral salen manganese(Ⅲ) complex into mesoporous silicates显示文摘 | FRUNZA L KOSSLICK H LANDNESSER H | 1997 | J Mol Catal A:Chemicals1997,123,23: | 1 |
| 10 | Perineural invasion in head and neck cancers-a review显示文摘 | Frunza A Slavescu D Lascar I | 2014 | J Med Life2014,7,2: | 1 |
| 11 | BiOx clusters occluded in a ZSM-5 matrix:preparation,characterization,and catalvtic behavior in liquid-phase oxidation of hydrocarbons显示文摘 | Dumitriu D Barjega R L Frunza D | 2003 | Journal of Catalysis2003,219,2: | 1 |
| 12 | Exploiting the systematic review protocol for classification of medical abstracts显示文摘 | Frunza O Inkpen D Matwin S | 2011 | Artificial Intelligence in Medicine2011,51,1: | 1 |
| 13 | Dynamic factor analysis of carbon allowances prices: From classic Arbitrage Pricing Theory to Switching Regimes显示文摘 | Frunza M C Gu e gan D Lassoudiere A | 2010 | 2010,,: | 1 |
| 14 | Some aspects of energy distribution in rotary forming processes 显示文摘 | CANTA T FRUNZA D SABADUS D TINTELECAN C | 1998 | Journal of Materials Processing Technology1998,8081,: | 1 |
| 15 | Derivative Pricing and Hedging on Carbon Market显示文摘 | Marius- Cristian Frunza Dominique Guegan | 2010 | Working Paper Series2010,,: | 1 |
| 16 | Msbius transformations in infinite dimensions 显示文摘 | Frunza M | 1991 | Rev Roumaine Math Pures Appl1991,36,: | 1 |
| 17 | Preparation and characterisation of PZT films by RF-magnetron sputtering显示文摘 | FRUNZA R RICINSCHI D GHEORGHIU F | 2011 | J Alloys Compd2011,509,21: | 1 |
| 18 | Mobius transformations in infinite dimensions显示文摘 | FRUNZA M | 1991 | Rev Roumaine Math Pures Appl1991,36,: | 1 |
| 19 | J Mol Catal A : Chem 显示文摘 | Frunza L Kosslick H Landnesserect H | 1997 | 123 : 1791997,123,: | 1 |
| 20 | BiOx clusters occluded in a ZSM-5 matrix: preparation, characterization, and catalytic behavior in liquid- phase oxidation of hydrocarbons 显示文摘 | Dumitriu D Bhrjega R Frunza L | 2003 | Journal of catalysis2003,219,2: | 1 |