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| 1 | Bismuth(Ⅲ)-and antimony(Ⅴ)-based ceramics with anion-deficient fluorite structure 显示文摘 | Champarnaud-Mesjard C Maniet M Frit B | 1992 | J Alloys Compd1992，188，： | 1 |
| 2 | The crystal chemistry and dielectric properties of the Aurivillius family of complex bismuth oxides with perovskite-like layered structures 显示文摘 | FRIT B MERCURIO J P | 1992 | J Alloy Compd1992，188，19： | 1 |
| 3 | The crystal chemistry and dielectric properties of the aurivillius family of complex bismuth oxide with perovskite-like layered structures 显示文摘 | Frit B Mercurio J P | 1992 | J Alloys Compds1992，188，： | 1 |
| 4 | Sol-gel synthesis, sintering and properties of a potassium-substituted cordierite显示文摘 | Thomas P Mercurio J P Frit B | 1989 | J Mater Sci Lett1989，8，1： | 1 |
| 5 | Percutaneous Coronary Intervention of Functionally Nonsignificant Stenosis显示文摘 | Nico H.J. Pijls Pepijn van Schaardenburgh Ganesh Manoharan Eric Boersma Jan-Willem Bech Marcel van't Veer Frits B?r Jan Hoorntje Jacques Koolen William Wijns Bernard de Bruyne | 2007 | Journal of the American College of Cardiology2007，，21： | 1 |
| 6 | The crystal chemistry and dielectric properties of the aurivillius family of complex bismuth oxides with perovskite-like layered structure显示文摘 | MERCURIO J P | 1992 | J Alloys Compd1992，188，： | 1 |
| 7 | The DNA repair complex DNA-PK,a pharmacological target in cancer chemotherapy and radiotherapy显示文摘 | SALLES B CALSOU P FRIT P | 2006 | Pathol Biol (Paris)2006，54，4： | 1 |
| 8 | The crystal chemistry and dielectric proper- ties of the Aurivillius family of complex oxides with perovskite- like layered structures 显示文摘 | Frit B Mercurio J P | 1992 | J Alloys Compd1992，188，： | 1 |
| 9 | High serum-free light chain levels and their rapid reduction in response to therapy define an aggressive multiple myeloma subtype with poor prognosis显示文摘 | FRITS V R VANESSA B KLAUS H | 2007 | Blood2007，110，： | 1 |
| 10 | The DNA repair complex DNA-PK, a pharmacological target in cancer chemotherapy and radiotherapy 显示文摘 | SALLES B CALSOU P FRIT P | 2006 | Pathol Biol ( Paris )2006，54，4： | 1 |
| 11 | The crystal chemistry and dielectric properties of the aurivillius family of complex bismuth oxide with perovskite-like layered structures 显示文摘 | FRIT B MERCURIO J P | 1992 | J Alloy Compound1992，188，： | 1 |
| 12 | The crystal chemistry and dielectric properties of the aurivillius family of complex bismuth oxide with perovskite-like layered structures 显示文摘 | FRIT B MERCURIO J P | 1992 | J Alloy Compound1992，188，19： | 1 |
| 13 | Global epidemiology of HIV infection in men who have sex with men显示文摘 | Chris B Baral SD Frits VG | 2012 | Lancet2012，380，1647： | 1 |
| 14 | The crystal chemistry and dielectric properties of the aurivillius family of complex bismuth oxides with perovskite-like layered structures 显示文摘 | FRIT B MERCURIO P J | 1992 | J Alloy Compd1992，188，： | 1 |
| 15 | Endoscopic Retroperitoneal Adrenalectomy: Lessons Learned From 111 Con secutive Cases显示文摘 | Jaap B Vera S Frits J et a l | 2000 | Ann Surgery2000，232，： | 1 |
| 16 | Bismuth (Ⅲ) - and antimony (V) - based ceramics with anion- deficient fluorite structure显示文摘 | Champarnaud - Mesjard J C Maniet M Frit B | 1992 | J Alloys Compd1992，188，： | 1 |
| 17 | DNA fingerprinting of vibrio cholerae strains with a novel insertion sequence element: a tool tl identify epidemic strains 显示文摘 | Elisabeth M B Richard D G Frits R M | 1996 | J Clin Microbiol1996，34，6： | 1 |
| 18 | The crystal chemistry and dielectric properties of the Aurivillius family of complex busmuth oxides with perovskite-like layered structures显示文摘 | Mercurio J P | 1992 | J Alloys Comp1992，188，： | 1 |
| 19 | Consumption of gluten with gluten-degrading enzyme by celiac patients: A pilot-study显示文摘AIM:To assesses the safety and efficacy of Aspergillus niger prolyl endoprotease(AN-PEP)to mitigate the im-munogenic effects of gluten in celiac patients.METHODS:Patients with initial diagnosis of celiac disease as confirmed by positive serology with subtotal or total villous atrophy on duodenal biopsies who adhere to a strict gluten-free diet(GFD)resulting in normalised antibodies and mucosal healing classified as Marsh 0 orⅠwere included.In a randomised double-blind placebo-controlled pilot study,patients consumed toast(approximately 7 g/d gluten)with AN-PEP for 2 wk(safety phase).After a 2-wk washout period with adherence of the usual GFD,14 patients were randomised to gluten intake with either AN-PEP or placebo for 2 wk(efficacy phase).Measurements at baseline included complaints,quality-of-life,serum antibodies,immunophenotyping of T-cells and duodenal mucosa immunohistology.Furthermore,serum and quality of life questionnaires were collected during and after the safety,washout and efficacy phase.Duodenal biopsies were collected after the safety phase and after the efficacy phase.A change in histological evaluation according to the modified Marsh classification was the primary endpoint.RESULTS:In total,16 adults were enrolled in the study.No serious adverse events occurred during the trial and no patients withdrew during the trial.The mean score for the gastrointestinal subcategory of the celiac disease quality(CDQ)was relatively high throughout the study,indicating that AN-PEP was well tolerated.In the efficacy phase,the CDQ scores of patients consuming gluten with placebo or gluten with AN-PEP did not significantly deteriorate and moreover no differences between the groups were observed.During the efficacy phase,neither the placebo nor the AN-PEP group developed significant antibody titers.The IgA-EM concentrations remained negative in both groups.Two patients were excluded from entering the efficacy phase as their mucosa showed an increase oftwo Marsh steps after the safety phase,yet with undetectable serum antibodies,while 14 patients were considered histologically stable on gluten with AN-PEP.Also after the efficacy phase,no significant deterioration was observed regarding immunohistological and flow cytometric evaluation in the group consuming placebo compared to the group receiving AN-PEP.Furthermore,IgA-tTG deposit staining increased after 2 wk of gluten compared to baseline in four out of seven patients on placebo.In the seven patients receiving AN-PEP,one patient showed increased and one showed decreased IgA-tTG deposits.CONCLUSION:AN-PEP appears to be well tolerated.However,the primary endpoint was not met due to lack of clinical deterioration upon placebo,impeding an effect of AN-PEP. | Greetje J Tack Jolanda MW van de Water Maaike J Bruins Engelina MC Kooy-Winkelaar Jeroen van Bergen Petra Bonnet Anita CE Vreugdenhil Ilma Korponay-Szabo Luppo Edens B Mary E von Blomberg Marco WJ Schreurs Chris J Mulder Frits Koning | 2013 | World Journal of Gastroenterology2013，19，35： | 1 |
| 20 | The hypolipidemic action of bezafibrate therapy in hypertriglyceridemia is mediated by upregulation of lipoprotein lipase: no effects on VLDL substrate affinity to lipolysis or LDL receptor binding显示文摘 | FEMKE D B ARNOUD V D L | 2000 | Atherosclerosis2000，153，2： | 1 |
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