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| 1 | High glucose suppresses human islet insulin biosynthesis by inducing miR-133a leading to decreased polypyrimidine tract binding protein-expression 显示文摘 | Fred RG Bang-Berthelsen CH Mandrup-Poulsen T | 2010 | PLoS One2010，5，10： | 1 |
| 2 | High glucose suppresses human islet insulin biosynthesis by inducing miR-133a leading to decreased polypyrimidine tract binding protein- expression显示文摘 | Fred RG Bang-Berthelsen CH Mandrup-Poulsen T | 2010 | PLoS One2010，5，10： | 1 |
| 3 | 上海天文馆显示文摘上海天文馆坐落于滴水湖畔,总面积约3.8万m^(2)作为上海科技馆分馆,是全球规模最大的天文学主题博物馆。其致力于营造沉浸式体验,让游客可以与各种天文现象直接互动,并通过对比例、形态以及光线的细致处理,提升人们对于太阳和地球轨道运动之间的基本关系的认知。 | 无 V.Guy Maxwell Grace Chen Wei Wei Kuang Charles Wolf Anthony Guaraldo Jorge Arias Margarita Calero Michael Caton Christina Ciardullo Eugene Colberg Regina Jiang Jörg Kiesow Aidan Kim Stefan Knust Xinya Li Francelle Lim Xiaoyun Mao David Monnar Nikita Payusov James Rhee Yong Kyun Roh Miya Ruan Na Sun Eric Tsui Stephanie Tung Charles Wong David Yu Fred Zhang | 2022 | 建筑实践2022，，5： | 1 |
| 4 | 浩瀚宇宙的秘密 上海天文馆显示文摘上海天文馆由Ennead建筑设计事务所设计合伙人Thomas J.Wong设计。其方案致力于营造沉浸式体验,让游客可以与各种天文现象直接互动,并通过对比例、形态以及光线的细致处理,提升人们对于太阳和地球轨道运动这一基本关系的认知。作为上海科技馆分馆,全新的上海天文馆占地38000 m^(2),为全球规模最大的天文学主题博物馆。 | 无 V.Guy Maxwell(设计) 陈昕昉(设计) 邝薇薇(设计) Charles Wolf(设计) Anthony Guaraldo(设计) Jorge Arias(设计) Margarita Calero(设计) Michael Caton(设计) Christina Ciardullo(设计) Eugene Colberg(设计) Regina Jiang(设计) Jörg Kiesow(设计) Aidan Kim(设计) Stefan Knust(设计) 李欣亚(设计) Francelle Lim(设计) Xiaoyun Mao(设计) David Monnar(设计) Nikita Payusov(设计) James Rhee(设计) Yong Kyun Roh(设计) 阮玲丽(设计) Na Sun(设计) 徐震(设计) Stephanie Tung(设计) 黄泽修(设计) 于乐川(设计) Fred Zhang(设计) | 2021 | 室内设计与装修2021，，9： | 1 |
| 5 | The Hi-receptor antagonist cetiri- zine protects partially against cytokine-and hydrogen peroxide-in- duced 15-TC6 cell death in vitro 显示文摘 | Anvari E Fred RG Welsh N | 2014 | Pancreas2014，43，4： | 1 |
| 6 | Natural DNA variation at candidate loci is associated with potato chip color, tuber starch content, yield and starch yield显示文摘 | Li Li Maria-Jo?o Paulo Josef Strahwald Jens Lübeck Hans-Reinhard Hofferbert Eckhart Tacke Holger Junghans J?rg Wunder Astrid Draffehn Fred Eeuwijk Christiane Gebhardt | | 0，，： | 1 |
| 7 | Plasma Aldosterone Is Independently Associated With the Metabolic Syndrome显示文摘 | Murielle Bochud Jürg Nussberger Pascal Bovet Marc R. Maillard Robert C. Elston Fred Paccaud Conrad Shamlaye Michel Burnier | 2006 | Hypertension2006，，2： | 1 |
| 8 | Dynamics and functions of E‑cadherin complexes in epithelial cell and tissue morphogenesis显示文摘Cell–cell adhesion is at the center of structure and dynamics of epithelial tissue.E-cadherin–catenin complexes mediate Ca^(2+)-dependent trans-homodimerization and constitute the kernel of adherens junctions.Beyond the basic function of cell–cell adhesion,recent progress sheds light the dynamics and interwind interactions of individual E-cadherin–catenin complex with E-cadherin superclusters,contractile actomyosin and mechanics of the cortex and adhesion.The nanoscale architecture of E-cadherin complexes together with cis-interactions and interactions with cortical actomyosin adjust to junctional tension and mechano-transduction by reinforcement or weakening of specific features of the interactions.Although post-translational modifications such as phosphorylation and glycosylation have been implicated,their role for specific aspects of in E-cadherin function has remained unclear.Here,we provide an overview of the E-cadherin complex in epithelial cell and tissue morphogenesis focusing on nanoscale architectures by super-resolution approaches and post-translational modifications from recent,in particular in vivo,studies.Furthermore,we review the computational modelling in E-cadherin complexes and highlight how computational modelling has contributed to a deeper understanding of the E-cadherin complexes. | Na Zhang Matthias Häring Fred Wolf Jörg Großhans Deqing Kong | 2023 | Marine Life Science & Technology2023，5，4： | 1 |
| 9 | Environmental determinants of access to shared sanitation in informal settlements:a cross-sectional study in Abidjan and Nairobi显示文摘Background Universal access to basic sanitation remains a global challenge,particularly in low-and middle-income countries.Efforts are underway to improve access to sanitation in informal settlements,often through shared facilities.However,access to these facilities and their potential health gains—notably,the prevention of diarrheal diseases—may be hampered by contextual aspects related to the physical environment.This study explored associations between the built environment and perceived safety to access toilets,and associations between the latter and diarrheal infections.Methods A cross-sectional study was carried out between July 2021 and February 2022,including 1714 households in two informal settlements in Abidjan(Côte d’Ivoire)and two in Nairobi(Kenya).We employed adjusted odds ratios(aORs)obtained from multiple logistic regressions(MLRs)to test whether the location of the most frequently used toilet was associated with a perceived lack of safety to use the facility at any time,and whether this perceived insecurity was associated with a higher risk of diarrhea.The MLRs included several exposure and control variables,being stratified by city and age groups.We employed bivariate logistic regressions to test whether the perceived insecurity was associated with settlement morphology indicators derived from the built environment.Results Using a toilet outside the premises was associated with a perceived insecurity both in Abidjan[aOR=3.14,95%confidence interval(CI):1.13–8.70]and in Nairobi(aOR=57.97,95%CI:35.93–93.53).Perceived insecurity to access toilets was associated with diarrheal infections in the general population(aOR=1.90,95%CI:1.29–2.79 in Abidjan,aOR=1.69,95%CI:1.22–2.34 in Nairobi),but not in children below the age of 5 years.Several settlement morphology features were associated with perceived insecurity,namely,buildings’compactness,the proportion of occupied land,and angular deviation between neighboring structures.Conclusions Toilet location was a critical determinant of perceived security,and hence,must be adequately addressed when building new facilities.The sole availability of facilities may be insufficient to prevent diarrheal infections.People must also be safe to use them.Further attention should be directed toward how the built environment affects safety. | Vitor Pessoa Colombo Jérôme Chenal Fred Orina Hellen Meme Jeanne d’Arc Amoin Koffi Brama Koné Jürg Utzinger | 2023 | Infectious Diseases of Poverty2023，12，2： | 0 |
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