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您的检索式：作者名="FrancoisSchiele"
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| 1 | Early local intracoronary platelet activation after drug-eluting stent placement显示文摘在冠的干预以后的背景早本地的血小板激活在尖锐 stent 血栓(著名计算机生产厂商) 的增加的风险识别病人。然而,早在跟随 drug-eluting stent ( DES )培植的冠的循环在血小板激活变化从来没是在 26 连续选任的马厩的未来的研究的 reported.Methods 咽峡炎病人,血小板激活被在 DES 或赤裸的金属 stent ( BMS )的培植前后测量可溶的 glycoprotein V ( sGPV )和 P-selectin ( CD62P )分析。所有病人是有 clopidogrel (300 mg 装载剂量) 和阿司匹林的 pretreated (75 mg 口头上地) 在过程前的日子。血样品从冠的口被拉并且 10 -对与更低的基线一致的损害 site.Results 远侧的 20 公里临床的风险, CD62P 和 sGPV 的层次在正常参考以内范围,两个在冠的口并且对在 CD62P 和 sGPV 的 procedure.The 层次没显著地改变的经皮的冠的干预(打印机控制语言)前的损害远侧( CD62P :(31.1 他们区域比率(1.13he 瘤是穿正常白人衣服的 evaluated.With creatinine | Ailiman Mahemuti Nicolas Meneveau Marie-France Seronde FrancoisSchiele Mariette Mercier Evelyne Racadotand Jean-Pierre Bassand | 2007 | Chinese Medical Journal2007，，22： | 3 |
| 2 | Clinical outcome of patients with left anterior descending artery ostial lesions treated with percutaneous coronary intervention; case-matched comparison with bypass surgery显示文摘Objective To assess the immediate and late clinical outcome of left anterior descending artery ostial lesions treated with percutaneous coronary intervention.Methods Seventeen patients (6 females and 11 males) treated with percutaneous coronary intervention for ostial left anterior descending artery stenoses have had clinical follow-ups over 12 months. Clinical events were defined as an occurrence of death, myocardial infarction, recurrent angina, and reguiring repeat revascularization (either by angioplasty or by surgery). A matched population treated with coronary bypass surgery was selected based on the similarities in age, left ventricular ejection fraction and the number of diseased vessels. Kaplan-Meier event-free survival curves were generated and the matched comparison was done using the Chi-square test (Mc Neimar method).Results In the catheter-based angioplasty group, the patients' mean age was 63±8 years. One patient was treated with directional atherectomy plus balloon, 6 with rotational atherectomy plus balloon, 7 with stent and 3 with rotational atherectomyplus stent. Glycoprotein Ⅱb/Ⅲa antagonist was used in 4 cases. Initial procedural success without major complications was achieved in all cases. The mean reference diameter was 2.90±0.48 mm. The minimum lumen diameter increased from 1.05±0.30 mm to 2.40±0.45 mm, and the diameter stenosis decreased from 64%±7% to 8%±13%. During the follow-up period, adverse events reguiring repeat revascularization occurred in 8 patients. The event-free probability was 0.42±0.14 in a two-year period. In a matched population treated with bypass surgery (single mammary graft), only one event occurred, and the difference in event-free survival in two-year period between the two patient groups was significant.Conclusions Percutaneous coronary intervention for left coronary descending artery ostial lesion is technically feasible and safe, leading to an optimal early success rate,but has a higher risk of late restenosis and greater need for repeat revascularization than coronary bypass surgery. | 刘品明 张少玲 FrancoisSchiele NicolasMeneveau Jean-PierreBassand | 2003 | Chinese Medical Journal2003，，6： | 0 |
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