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4篇 您的检索式:作者名="Francesca Aquila"
    题名 作者 年代 出处 被引量
1猪精子细胞中胰岛素诱导产生的一氧化氮自由基促进精子获能显示文摘近期,胰岛素被证实具有诱导猪精子获能的能力。在不同的哺乳动物中,精子获能被认为与一氧化氮信号通路相关;因此,本研究使用荧光激活细胞分选技术探究经胰岛素处理的猪精子中一氧化氮水平。在同一样本中,用金霉素染色、蛋白质酪氨酸磷酸化模式和顶体状态来评估精子获能。结果显示经胰岛素处理的精子内一氧化氮水平及三种评价精子获能的指标均有显著提高;相反,用一氧化氮合成酶抑制剂(N-硝基-L-精氨酸甲酯)或抗胰岛素受体β抗体预处理的精子中胰岛素相关的作用全被逆转。这些结果表明胰岛素具有增强猪精子细胞内一氧化氮浓聚的能力并且提示胰岛素可能通过一氧化氮促进精子获能。Saveria Aquila Francesca Giordano Carmela Guido Vittoria Rago Amalia Carpino 2013Asian Journal of Andrology2013,15,6:2
2Acute left-sided malignant colonic obstruction:Is there a role for endoscopic stenting?显示文摘The therapy of left-sided malignant colonic obstruction continues to be one of the largest problems in clinical practice.Numerous studies on colonic stenting for neoplastic colonic obstruction have been reported in the last decades.Thereby the role of self-expandable metal stents(SEMS)in the treatment of malignant colonic obstruction has become better defined.However,numerous prospective and retrospective investigations have highlighted serious concerns about a possible worse outcome after endoscopic colorectal stenting as a bridge to surgery,particularly in case of perforation.This review analyzes the most recent evidence in order to highlight pros and cons of SEMS placement in left-sided malignant colonic obstruction.Salvatore Russo Rita Conigliaro Francesca Coppini Emanuela Dell'Aquila Giuseppe Grande Flavia Pigò Santi Mangiafico Marinella Lupo Margherita Marocchi Helga Bertani Silvia Cocca 2023World Journal of Clinical Oncology2023,14,5:0
3A peptide-based assay discriminates individual antibody response to SARS-CoV-2显示文摘SARS-CoV-2 virus is responsible for the current worldwide coronavirus disease 2019 (COVID-19) pandemic, infecting millions of people and causing hundreds of thousands of deaths. Understanding the antibody response to SARS-CoV-2 is crucial for the development of vaccines, therapeutics and public health interventions. However, lack of consistency in methods used to monitor antibody response to SARS-CoV-2 leaves some uncertainty in our fine understanding of the human antibody response mounted following SARS-CoV-2 infection. We developed a peptide-based enzyme-linked immunosorbent assay (ELISA) by selecting 7 synthetic peptides from the spike, membrane, and nucleocapsid protein sequences of SARS-CoV-2, which effectively detects the antibody response mounted by all COVID-19 convalescent tested. Strikingly, the assay shows a profound difference in antibody response among individual subjects, which may have a significant impact on disease severity. Together, our results define an efficient and specific serological assay to consistently measure the antibody response following SARS-CoV-2 infection, as well as help the design of vaccine and therapeuticals for prevention and treatment of COVID-19.Immacolata Polvere Serena Voccola Gaetano Cardinale Maurizio Fumi Francesca Aquila Alfredina Parrell Jessica Raffaella Madera Romania Stilo Pasquale Vito Tiziana Zotti 2022Genes & Diseases2022,9,1:0
4The Subtle Sound of Learning: What Are the Roles of the Self-esteem, Decision-Making, and Social Skills in Adolescents' Academic Performance?显示文摘Pina Filippello Luana Sorrentit Francesca CuzzocreaUniversity of Messina Messina Antonella NuzzaciUniversity of L'Aquila, L'Aquila Rosalba LarcanUniversity of Messina,Messina, Italy 2014US-China Education Review(B)2014,4,2:0
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