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| 1 | Clinical outcomes of compensated and decompensated cirrhosis: A long term study显示文摘AIM: To study these characteristics and prognostic patterns in a Greek patient population.METHODS: We analyzed a large cohort of cirrhotic patients referred to the department of Gastroenterology and Hepatology and the outpatient clinics of this tertiary hospital, between 1991 and 2008. We included patients with established cirrhosis, either compensated or decompensated, and further decompensation episodes were registered. A data base was maintained and updated prospectively throughout the study period.We analyzed differences in cirrhosis aetiology, time to and mode of decompensation, hepatocellular carcinoma(HCC) occurrence and ultimately patient survival.RESULTS: Five hundreds and twenty-two patients with median age 67(range, 29-91) years and average follow up 9 years-10 mo(range, 1-206 mo) were studied. Commonest aetiology was hepatitis C virus(HCV, 41%) followed by alcohol(31%). The median survival time in compensated cirrhotics was 115 mo(95%CI: 95-133), whereas in decompensated patients was 55 mo(95%CI: 36-75). HCV patients survived longer while HBV patients had over twice the risk of death of HCV patients. The median time to decompensation was 65 mo(95%CI: 51-79), with alcoholics having the highest risk(RR = 2.1 vs HCV patients). Hepatitis B virus(HBV) patients had the highest risk of HCC, alcoholics the lowest. Leading causes of death: liver failure, hepatorenal syndrome, sepsis and HCC progression. CONCLUSION: Cirrhosis aetiology and decompensation at presentation were predictors of survival. Alcoholics had the highest decompensation risk, HBV cirrhotics the highest risk of HCC and HCV cirrhotics the highest decompensation-free time. | Dimitrios N Samonakis Mairi Koulentaki Constantina Coucoutsi Aikaterini Augoustaki Chryssavgi Baritaki Emmanuel Digenakis Nikolaos Papiamonis Maria Fragaki Erminia Matrella Elias A Kouroumalis Maria Tzardi | 2014 | World Journal of Hepatology2014，6，7： | 4 |
| 2 | Comparison of effectiveness of ranolazine plus amiodarone versus amiodarone alone for conversion of recent-onset atrial fibrillation显示文摘 | Fragakis N Koskinas KC Katritsis DG | 2012 | Am J Cardiol2012，110，5： | 1 |
| 3 | Reversion and maintenance of sinus rhythm in patients with permanent atrial fibrillation by internal cardioversion by biatrial pacing 显示文摘 | Fragakis N Shakepeare CF Lloyd G | 2002 | PACE2002，25，： | 1 |
| 4 | Brugada type electrocardiographic changes induced by concomitant use of lithium and propafenone in patient with Wolff-Parkinson-White syndrome显示文摘 | Fragakis N Iliadis I Papanastasiou S | 2007 | Pacing Clin Electrophysiol2007，30，6： | 1 |
| 5 | Comparison of effectiveness of ranolazine plus amiodarone versus amiodarone alone for conversion of recent-on- set atrial fibrillation显示文摘 | Fragakis N Koskinas KC Katritsis DG | 2012 | Am J Cardiol2012，110，： | 1 |
| 6 | Trimetazidine administration minimizes myocardial damage and improves left ventricular function after percutaneous coronary intervention显示文摘 | Labrou A Giannoglou G Zioutas D Fragakis N | | 0，，02： | 1 |
| 7 | Efcacy and safety of ibutilide for cardioversion of atrial flutter and fibrillation in Patients receiving amiodarone or propafenone显示文摘 | Fragakis N Papadopoulos N Papanastasiou S | 2005 | Pacing Clin Electrophysiol2005，28，9： | 1 |
| 8 | Reversion and maintenance of sinus rhythm in patients with permanent atrial fibrillation by internal cardioversion by biatrial pacing 显示文摘 | Fragakis N Shakepeare CF Lloyd G | 2002 | PACE2002，25，： | 1 |
| 9 | Conditions for aggregation of CHP plants in the UK electricity market and exploration of plant size显示文摘 | FRAGAKI A ANDERSEN A N | | 0，，11： | 1 |
| 10 | Reversion and maintenance of sinus rhythm in patients with permanent atrial fibrillation by internal cardioversion followed by biatrial pacing显示文摘 | Shakespeare CF Lloyd G | 2002 | PACE2002，25，3： | 1 |
| 11 | Efficacy and safety of ibutilide for cardioversion of atrial flutter and fibrillation in patients receiving amiodarone or propafenone显示文摘 | Fragakis N Papadopoulos N Papanastasiou S | | 0，，09： | 1 |
| 12 | Efficacy and safety of ibtilide for cardivoversion of atrial flutter and fibrillation in patients receiving amiodarone or propafenone 显示文摘 | Fragakis N Papadopoulos N Papanastasion S | 2005 | Pacing Clin Electrophysiol2005，28，9： | 1 |
| 13 | Exploration of e-conomical sizing of gas engine and thermal store for combined heat and power plants in the UK 显示文摘 | Fragaki A Andersen A N Toke D | 2008 | Ener- gy2008，33，11： | 1 |
| 14 | Conditions for aggregation of CHP plants in the UK electricity market and exploration of plant size 显示文摘 | AiKaterini Fragaki Anders N Andersen | 2011 | Applied Energy2011，88，11： | 1 |
| 15 | Reversion and maintenance of sinus rhythm in patients with permanent atrial fibrillation by internal cardioversion by biatrial pacing 显示文摘 | Fragakis N Shakepeare CF Lloyd G | 2007 | PACE2007，25，： | 1 |
| 16 | Acute beta-adrenoceptor blockade improves efficacy of ibutilide in conversion of atrial fibrillation with a rapid ventricular rate 显示文摘 | Fragakis N Bikias A Delithanasis I | 2009 | Europace2009，11，1： | 1 |
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