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| 1 | Comparative outcome of stapled trans-anal rectal resection and macrogol in the treatment of defecation disorders显示文摘AIM:To prospectively assess the eff icacy and safety of stapled trans-anal rectal resection(STARR) compared to standard conservative treatment,and whether preoperative symptoms and findings at defecography and anorectal manometry can predict the outcome of STARR.METHODS:Thirty patients(Female,28;age:51 ± 9 years) with rectocele or rectal intussusception,a defecation disorder,and functional constipation were submitted for STARR.Thirty comparable patients(Female,30;age 53 ± 13 years),who presented with symptoms of rectocele or rectal intussusception and were treated with macrogol,were assessed.Patients were interviewed with a standardized questionnaire at study enrollment and 38 ± 18 mo after the STARR procedure or during macrogol treatment.A responder was def ined as an absence of the Rome Ⅲ diagnostic criteria for functional constipation.Defecography and rectoanal manometry were performed before and after the STARR procedure in 16 and 12 patients,respectively.RESULTS:After STARR,53% of patients were responders;during conservative treatment,75% were responders.After STARR,30% of the patients reported the use of laxatives,17% had intermittent anal pain,13% had anal leakage,13% required digital facilitation,6% experienced defecatory urgency,6% experienced fecal incontinence,and 6% required re-intervention.During macrogol therapy,23% of the patients complained of abdominal bloating and 13% of borborygmi,and 3% required digital facilitation.No preoperative symptom,defecographic,or manometric finding predicted the outcome of STARR.Post-operative defecography showed a statistically significant reduction(P < 0.05) of the rectal diameter and rectocele.The postoperative anorectal manometry showed that anal pressure and rectal sensitivity were not significantly modified,and that rectal compliance was reduced(P = 0.01).CONCLUSION:STARR is not better and is less safe than macrogol in the treatment of defecation disorders.It could be considered as an alternative therapy in patients unresponsive to macrogol. | Ivano Biviano Danilo Badiali Laura Candeloro Fortunée Irene Irene Habib Massimo Mongardini Angelo Caviglia Fiorella Anzini Enrico S Corazziari | 2011 | World Journal of Gastroenterology2011，17，37： | 3 |
| 2 | A method to find community structures based on information centrality显示文摘 | FORTUNATE S LATORA V MARICHIORI M | 2004 | Physical Review E2004，70，05： | 1 |
| 3 | Benchmark 'aphs for tes- ting community detection algorithms 显示文摘 | Lancichinetti A Fortunate S Radicchi F | 2008 | Physial Review E2008，78，4： | 1 |
| 4 | FSH and growth factors affeet the growth and endocrine function in vitro of granulose cells of bovine preantral follicles显示文摘 | Wandji S A Eppig J J Fortune J E | 1996 | Theriogenology1996，45，4： | 1 |
| 5 | Deliberate self harm in chil dren and adolescents: a research update显示文摘 | FORTUNE S A HAWTON K | 2005 | Curropin Psyc hiatry2005，18，40： | 1 |
| 6 | Comparing muhifocal VEP and standard automated perimetry in high-risk ocular hypertension and early glaucoma 显示文摘 | Fortune B Demirel S Zhang X | 2007 | Invest Ophthalmol Vis Sci2007，48，： | 1 |
| 7 | A sweepline algorithm for Voronoi Diagrams显示文摘 | FORTUNE S | 1987 | Algorithmica1987，2，2： | 1 |
| 8 | Comparing muhifocal VEP and standard automated perimetry in high-risk ocular hypertension and early glaucoma显示文摘 | Fortune B Demirel S Zhang X | 2007 | Invest Ophthalmol Vis Sci2007，48，3： | 1 |
| 9 | The relationship between path- ologicaI gambling and sensation seeking: the role of subscale scores显示文摘 | FORTUNE E E G(X)DIE A S | 2010 | J Gambling Stud2010，26，3： | 1 |
| 10 | Prediction of net energy value of feeds for growing pigs显示文摘 | Noblet J Fortune H Shi X S | 1994 | J Anim Sci1994，72，： | 1 |
| 11 | Prediction of net energy values for growing pigs 显示文摘 | NOBLET J FORTUNE H SHI X S | 1994 | Journal of Animal Science1994，72，2： | 1 |
| 12 | A Sweepline Algorithm for Voronoi Diagrams显示文摘 | FORTUNE S | 1987 | Algorithmica 21987，，： | 1 |
| 13 | The role of endothelial nitricoxide synthase (eNOS) genetic variants in European patients withintracranial aneurysms显示文摘 | Krex D Fortun S Kuhlisch E | 2006 | J Cereb Blood Flow Metab2006，26，10： | 1 |
| 14 | Effects of sulphur on yield and malting quality of barley显示文摘 | Zhao FJ Fortune S Barbosa VL | 2006 | Journal of Cereal Science2006，43，3： | 1 |
| 15 | A sweep-line algorithm for Voronoi diagrams显示文摘 | FORTUNE S | 1987 | Algorithmica1987，2，2： | 1 |
| 16 | Mutually dependent secretion of proteins required for mycobacterial virulence显示文摘 | Fortune S M Jaeger A Sarracino D A | 2005 | Proc Natl Acad Sci U S A2005，102，10： | 1 |
| 17 | Voronoi diagrams and delaunay triangulations 显示文摘 | Fortune S | 1992 | Computing in Euclidean Geometry1992，1，： | 1 |
| 18 | Benchmark graphs for testing community detection algorithms 显示文摘 | LANCICHINETTI A FORTUNATe S RADICCHI F | 2008 | Physical Review E: Statistical Nonlinear and Soft Matter Physics2008，78，04： | 1 |
| 19 | Risk factors for invasive aspergillosis in liver transplant recipients显示文摘 | Fortun J Martin-Davila P Moreno S | 2002 | Liver Transplant2002，8，11： | 1 |
| 20 | Comparing muhifo- cal VEP and standard automated perimetry in high-risk ocular hypertension and early glaucoma显示文摘 | Fortune B Dcmircl S Zhang X | 2007 | Invest Oph- thalmol Vis Sci2007，48，3： | 1 |
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