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| 1 | New development thoughts on the bio-inspired intelligence based control for unmanned combat aerial vehicle显示文摘Bio-inspired intelligence is in the spotlight in the field of international artificial intelligence,and unmanned combat aerial vehicle(UCAV),owing to its potential to perform dangerous,repetitive tasks in remote and hazardous,is very promising for the technological leadership of the nation and essential for improving the security of society.On the basis of introduction of bioinspired intelligence and UCAV,a series of new development thoughts on UCAV control are proposed,including artificial brain based high-level autonomous control for UCAV,swarm intelligence based cooperative control for multiple UCAVs,hy-brid swarm intelligence and Bayesian network based situation assessment under complicated combating environments, bio-inspired hardware based high-level autonomous control for UCAV,and meta-heuristic intelligence based heterogeneous cooperative control for multiple UCAVs and unmanned combat ground vehicles(UCGVs).The exact realization of the proposed new development thoughts can enhance the effectiveness of combat,while provide a series of novel breakthroughs for the intelligence,integration and advancement of future UCAV systems. | DUAN HaiBin 1 ,SHAO Shan 2 ,SU BingWei 3 &ZHANG Lei 41 State Key Laboratory of Science and Technology on Holistic Flight Control,School of Automation Science and Electrical Engineering, Beijing University of Aeronautics and Astronautics,Beijing 100191,China 2 Flight Control Department,Shenyang Aircraft Design and Research Institute,Shenyang 110035,China 3 Beijing Institute of Near Space Vehicle’s System Engineering,Beijing 100076,China 4Integration and Project Section,Air Force Equipment Academy,Beijing 100085,China | 2010 | Science China(Technological Sciences)2010，53，8： | 32 |
| 2 | 海洋工程技术强国战略显示文摘为了推进海洋强国建设,中国工程院于2011年启动了'中国海洋工程与科技发展战略研究'重大咨询项目研究。本文从海洋探测、海洋运载、海洋能源、海洋生物资源、海洋环境和海陆关联6个重要工程技术领域开展咨询调查研究,系统分析了海洋工程与科技发展的机遇与战略需求,提出了发展战略和任务。明确提出建设海洋强国,科技必须先行,必须首先建设海洋工程技术强国,建议国家加大海洋工程技术的发展力度,加快实施海洋工程科技创新驱动和现代海洋产业发展推进两大计划。 | Task Force for the Study on Development Strategy of China’s Marine Engineering and Technology Comprehensive Research Group | 2016 | 中国工程科学2016，18，2： | 9 |
| 3 | 世界海洋工程与科技的发展趋势与启示显示文摘本文通过对世界海洋工程与科技发展所呈现的海洋开发技术和设备不断进步推动海洋资源全面开发利用,海洋能源开发利用已成为各海洋国家发展的重要支柱,海洋生物资源开发一直是世界各国竞争热点,海洋污染控制和防范受到国际社会的高度关注,海陆关联工程与技术在现代海洋开发中发挥越来越重要的作用等特点与趋势的梳理与分析,获得如下启示:强化全民海洋意识,推进海洋强国战略;加强科技创新,提升海洋工程与科技的竞争力;优化产业结构,大力扶持海洋新兴产业;健全管理体制,建立协调发展机制;加强海洋保护,保障资源可持续利用。 | Task Force for the Study on Development Strategy of China’s Marine Engineering and Technology Comprehensive Research Group | 2016 | 中国工程科学2016，18，2： | 6 |
| 4 | The ratio of MMP-2 to TIMP-2 in hilar cholangiocarcinoma:a semi-quantitative study显示文摘BACKGROUND: Hilar cholangiocarcinoma is associated with low resectability and poor survival. The aim of this study was to evaluate the roles of matrix metalloproteinases- 2 (MMP-2 ) and its tissue inhibitor of metalloproteinase-2 (TIMP-2) in tumor invasion or as a prognostic factor in patients with human hilar cholangiocarcinoma. METHODS: The expressions of MMP-2 and TIMP-2 were investigated in patients. Paraffinized tissue sections ob- tained from 50 patients with human hilar cholangiocarcino- ma were analysed. The expressions of MMP-2 and TIMP-2 were examined immunohistochemically. Image analysis with image-pro plus analysis software was used to semi- quantitatively determine the ratio of MMP-2 to TIMP-2. RESULTS: The expression levels of MMP-2 and TIMP-2 were strongly associated with tumor hepatic invasion in pa- tients with hilar cholangiocarcinoma. Significant diffe- rences in the ratio of MMP-2 to TIMP-2 between some pathologic factors were observed in patients with hilar cholangiocarcinoma. CONCLUSIONS: MMP-2 plays an essential role in tumor invasion and metastasis,while TIMP-2 is shown to strongly inhibit cancer invasion and metastasis. The ratio of MMP-2 to TIMP-2 may be a prognostic indicator for patients with hilar cholangiocarcinoma. | Mei Xiao, Nin-Xing Zhou,Zhi-Qiang Huang,Ya-Li Lu, Ling-Hong Chen, Dian-Jun Wang and Wei-Lin Chang Beijing, China Department of Hepatobiliary Surgery, General Air- force of Hospital, Beijing 100036, China and General Hospital of People’ s Liberation Army, Beijing 100853 , China | 2004 | Hepatobiliary & Pancreatic Diseases International2004，3，4： | 5 |
| 5 | Study of the effect of atorvastatin on the interaction between ICAM-1 and CD11b by live-cell single-molecule force spectroscopy显示文摘The interaction between the cell adhesion molecule CD11b and its ligand ICAM-1 plays an important role in inflammatory responses in the disease of atherosclerosis. Atorvastatin is a commonly prescribed statin drug which has been considered as one of the most potent therapeutic agents for atherosclerosis due to its lipid-lowering effect. Recently, there is a growing body of evidence that atorvastatin has anti-inflammatory effect. We have applied the advanced method of live-cell single-molecule force spectroscopy to investigate the effect of atorvastatin on adhesion force between ICAM-1 and CD11b. Our result showed that single-molecule binding force of ICAM-1 and CD11b detected by AFM in the living cells was about 40 pN, and atorvastatin did not affect this force by blocking ICAM-1 or CD11b. This was different from the ICAM-1 monoclonal antibody, which could directly reduce the binding force of ICAM-1 and CD11b. Flow cytometry results revealed that atorvastatin pretreatment decreased the ICAM-1 expression in TNF-α activated HUVECs, which may contribute to its anti-inflammatory effect. The study provides a new approach to study anti-inflammatory mechanism for clinic drugs. | LI Yi1, SHI XiaoLi2, LIU HuiLiang1, YI ShaoQiong3, ZHANG XueJie2 & FANG XiaoHong2 1Department of Cardiology, the General Hospital of Chinese People’s Armed Police Forces, Beijing 100039, China 2Beijing National Laboratory for Molecular Sciences Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China 3State Key Laboratory of Pathogen and Biosecurity Beijing Institute of Microbiology and Epidemiology, Beijing 100071, China | 2010 | Science China Chemistry2010，53，4： | 2 |
| 6 | Studies on Human Fetal Lens Crystallins Under Oxidative Stress and Protective Effects of Tea Polyphenols显示文摘Purpose: To investigate the oxidative modification of water-soluble crystallins of human fetal lens with H2O2 and fourteen metal ions with or without EDTA. Tea-polyphenols (TP) was added to above solutions in order to testing their antioxidative abilities. Methods: The experiments were performed at 37℃ with final concentration of 2.5mg/ml protein, 0.1 mM metal ions, 0.3 mM EDTA and 1.0 mM H2O2. Then the TP was added to the solution with CuSO4 and H2O2, after 5 or 24 hours, the crystallins were analysed with SDS-PAGE and IEF.Results : There were marked oxidative modifications of lens protein in H2O2 and copper without EDTA. In SDS-PAGE patterns, we found an increase in those species above of bands higher than 30 kD and some diffuse bands from 30 to 17 kD after 5 hours. In IEF patterns, there were a general increase on acidity with loss of the more basic species. When the TP was added, there was not any difference with control group.Conclusion: The results indicate that exposure of water-soluble | Hui Xiang, Suhua Pan, Shaozhen LiGuangdong Provincial Corps Hospital, Chinese People’ s Armed Police Forces, Guangzhou 510010, China Zhongshan Ophthalmic Center, Sun Yat-sen University of Medical Sciences, Guangzhou 510060, China | 1998 | 眼科学报1998，14，3： | 2 |
| 7 | CLinicalpathologic conference in general thoracic surgery:pulmonary blastoma显示文摘 | Force S Patterson GA | 2003 | J Thorac Cardiovasc Surg2003，126，5： | 1 |
| 8 | Vulvovaginal candidiasis:epidemiologic,diagnostic,and therapeutic considerations显示文摘 | Sobel JD Faro S Force RW | 1998 | Am J Obstet Gynecol1998，178，2： | 1 |
| 9 | Cationic Lipid:Bacterial DNA Complexes E1icit Adaptive Cellular Immunity in Murine Intraperitoneal Tumor Models显示文摘 | Rudginsky S Force S D | 2000 | Cancer Res2000，60，： | 1 |
| 10 | Study in non-pressure-treated versus pressure-treated hypertrophic scars显示文摘 | Costa AM Peyrol S Porto LC Mechanical forces induce scar remodeling | 1999 | Am J Pathol1999，155，5： | 1 |
| 11 | Clinical-pathologic conference in general thoracic surgery : pulmonary blastoma 显示文摘 | Force S Patterson GA | 2003 | J Thoracic Cardiovascular Surg2003，126，： | 1 |
| 12 | IEEE reliability test system显示文摘 | Force T S T | 1979 | IEEE Transactions on Power Apparatus and Systems1979，98，6： | 1 |
| 13 | New fluorescence parameters for monitoring photosynthesis in plants 显示文摘 | FORCE L CRITCHLEY C VAN RENSEN J J S | 2003 | Photosvnth Res2003，78，： | 1 |
| 14 | Vulvovaginal candidiasis: epidemiologic, diagnostic, and therapeutic considerations显示文摘 | SOBEL J D FARO S FORCE R W | 1998 | Am J Obstet Gynecol1998，178，2： | 1 |
| 15 | 2014 ESC/EACTS Guidelines on myocardial revascularization: The Task Force on Myocardial Revascularization of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoraeic Surgery (EACTS)Devel- oped with the special contribution of the European Asso- ciation of Percutaneous Cardiovascular Interventions(EAP- CI)显示文摘 | Task Force members Windecker S Kolh P | 2014 | Eur Heart J2014，35，37： | 1 |
| 16 | New fluorescence parameters for monitoring photosynthesis in plants显示文摘 | Force L Critchley C van Rensen J J S | 2003 | Photo- synthesis Research2003，78，1： | 1 |
| 17 | Temporal changes in soil partitioning and bioaccessibility of arsenic,chromium,and lead显示文摘 | Fendorf S La Force M J Li G | 2004 | Journal of Environmental Quality2004，33，： | 1 |
| 18 | 6 to 6umRange 显示文摘 | Lamoreaux S K Demonstration of the Casimir Force in the 0 | 1997 | Phys Rev Lett1997，78，： | 1 |
| 19 | Temporary thoracoscopic sympathetic block for hyperhidrosis显示文摘 | Miller D L Force S D | 2008 | Ann Thorac Surg2008，85，4： | 1 |
| 20 | New fluores cence parameters for monitoring photosynthesis in plants显示文摘 | Force L Critchley C van Rensen J J S | 2003 | Pbotosynth Res2003，78，： | 1 |
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