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47篇 您的检索式:作者名="Fonn"
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1氧气与角膜接触镜配戴(英文)显示文摘全球大约有八千万人 (约占总人口的 1.5 % )在配戴角膜接触镜 ,镜片的透氧性及配戴角膜接触镜后角膜的获氧状态是保证配戴安全性和有效性的关键。角膜需要多种营养物质以保证其正常的代谢功能 ,氧气是其中是重要的部分 ,只有在充分氧供的状态下 ,角膜才能保持稳定的 78%的水合状态 ,保证角膜透明性。为了进一步了解氧气与角膜接触镜配戴的关系 ,本文着重对角膜接触镜所致的角膜缺氧的主要表现及角膜接触镜的透氧性能及其表达指标作一综述。配戴角膜接触镜后 ,角膜的氧供明显减少 ,特别在闭眼状态下氧供减少尤其明显 ,角膜接触镜引起的角膜缺氧变化主要表现为 :①角膜上皮 :角膜上皮水肿 ,即因细胞间隙中水液充盈而发生的微囊样水肿 ,水肿明显时会影响视力并使角膜的敏感性下降 ;②角膜基质 :角膜基质水肿达 5 %以上即可从裂隙灯检查中发现 ,主要表现为条纹或皱褶 ,长期慢性水肿会诱发角膜新生血管的发生 ,逐步发生角膜疤痕、屈光改变等一系列问题 ;③角膜内皮 :慢性角膜缺氧最终会导致角膜内皮细胞形态的改变 ,而且无法代偿。保持角膜功能的最低需氧量称为“临界氧” ,理想的角膜接触镜应该是通过该镜片后到达角膜面的氧供超过临界氧。角膜接触镜的透氧性能表达指标主要有 :透氧性王建华 Desmond Fonn Renee Du Toit 1999眼视光学杂志1999,1,3:6
2Spring phytoplankton bloom in Norwegian coastal waters:microbial community dynamics,succession and diversity显示文摘Larsen A Fonnes GA Sandaa RA 0,,:1
3Contact lens induced comeal swelling and surface changes measured with the Orbscan Ⅱ corneal topographer显示文摘Moezzi AM Fonn D Simpson TL 2004Optom Vis Sci2004,81,3:1
4Comparison of an objective method of measuring bulbar redness to the use of traditional grading scales显示文摘Luigina Sorbara Trefford Simpson Stephanie Duench Marc Schulze Desmond Fonn 2007Contact Lens and Anterior Eye2007,,1:1
5A patient questionnaire approach to estimating the prevalence of dry eye symptoms in pa- tients presenting to optometric practices across Canada 显示文摘Doughty MJ Fonn D Richter D 1997Optom Vis Sci1997,74,8:1
6Benents and cnallenges of high-DK/t materials显示文摘Desmond Fonn 2005Contact lens Spectator2005,20,:1
7Sympathetic swelling response of the control eye to soft lenses in the other eye显示文摘 du Toit R Simpson TL 1999Invest Ophthalmol Vis Sci1999,40,13:1
8Objective measurements of corneal light- backscatter during corneal swelling, by optical coherence tomography 显示文摘Wang J Simpson TL Fonn D 2004Invest Ophthalmol Vis Sci2004,45,:1
9Benefits of silicone hydrogel lenses显示文摘Desmond Fonn 2006Contact Lens Spectrum2006,21,2:1
10Contact lens-induced corneal swelling and surface changes measured with the Orhscan Ⅱ corneal topographer显示文摘Moezzi AM Fonn D Simpson TL 2004Optom Vis Sci2004,81,3:1
11Outcomes of wavefront-guided laser in situ keratomileusis for hyperopia显示文摘Nancy J. Keir Trefford Simpson Natalie Hutchings Lyndon Jones Desmond Fonn 2011Journal of Cataract & Refractive Surgery2011,,5:1
12Hydroxylation ofprimisulfuron by an inducible cytochrome P450 dependentmonooxygenase system from maize显示文摘FONNE F R GAUDIN J KREUZ 2001Pestic Biochem Physiol2001,37,:1
13Hydroxylation ofprimisulfuron by an inducible cytochrome P450 dependentmonooxygenase system from maize显示文摘FONNE F R GAUDIN J KREUZ 2001Pestic Biochem Physiol2001,37,:1
14Wavefront-guided LASIK for myopia:effect on visual acuity,contrast sensitivity, and higher order aberrations 显示文摘KEIR N J SIMPSON T JONES LW FONN D 2009J Refract Surg2009,25,6:1
15Precorneal and pre-and post-lens tear film thickness measured indirectly with optical coherence tomography显示文摘Wang J Fonn D Simpson TL 2003Invest Ophthalmol Vis Sci2003,44,6:1
16Recombinant leucocyte A interferon: and active agent in advanced cutaneous T-cell lymphomas显示文摘 Fonn KA Ihde DC 1984Ann Intem Med1984,101,4:1
17Hydrogel lens dehydration and subjective comfort and dryness ratings in symptomatic and asymptomatic contact lens wearers显示文摘Fonn D Situ P Simpson T 1999Optometry and Vision Sci1999,76,10:1
18Topographical thickness of the epithelium and total cornea after overnight wear of reverse-geometry rigid contact lenses for myopia reduction显示文摘Wang J Fonn D Simpson TL 2003Invest Ophthalmol Vis Sei2003,44,11:1
19Hydroxylation of primisulfuron by an inducible cytochrome P450 dependent monooxygenase system from maize显示文摘Fonne F R Gaudin J Kreuz 1990Pestic Biochem Physiol1990,37,:1
20Patient preferences and comparative ocular responses to rigid and soft contact lenses显示文摘FONN D GAUTHIER CA PRITCHARD N 1995Optom Vis Sci1995,72,:1
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