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| 1 | Gender development and hepatitis B and C infections among pregnant women in Africa:a systematic review and metaanalysis显示文摘Background:Although Africa is a region of hyper endemicity to viral hepatitis B(HBV)and C(HCV)infections,there is limited data on their related burden among pregnant women.The present systematic review and meta-analysis aimed to determine the magnitude of these infections among pregnant women living in Africa and investigate its association with gender-related human development indicators.Main text:We searched PubMed,Embase,Web of Science,Africa Journal Online,and Global Index Medicus,with no language restriction,to identify observational studies on HBV and HCV infections in pregnant women residing in Africa published from January 1,2000 until December 31;2017.Eligible studies reported the prevalence of HBV and/or HCV infection(s)(HBs antigen and HCV antibodies)and/or infectivity(HBe antigen or detectable HCV viral load).Each study was independently reviewed for methodological quality.We used a random-effects model metaanalysis to pool studies.In total,145 studies(258251 participants,30 countries)were included,of which 120(82.8%)had a low,24(16.5%)a moderate,and one(0.7%)had a high risk of bias.The prevalence of HBV and HG/infections was 6.8%(95%confidence interval[CI]:6.1-7.6,113 studies)and 3.4%(95%CI:2.6-A.2,58 studies),respectively.The prevalence of HBe antigen and HCV detectable viral load was 18.9%(95%CI:14.4-23.9)and 62.3%(95%CI:51.6-72.5)in HBV positive and HCV positive pregnant women,respectively.The multivariable meta-regression analysis showed that the prevalence of HBV infection increased with decreasing gender development index,males,level of education and females'expected years of schooling.Furthermore,this prevalence was higher in rural areas and in western and central Africa.The prevalence of HCV infection increased with decreasing proportion of seats held by women in parliament.Conclusions:To address the burden of HBV and HCV infections,beyond well-known risk factors at the individual-level,macro-level factors including gender-related human development indicators and dwelling in rural areas should be considered.In Africa,HBV or HCV infeaed mothers seems to have high potential of transmission to their children. | Jean Joel Bigna Angeladine M.Kenne Aghiles Hamroun Marie S.Ndangang Audrey Joyce Foka Dahlia Noelle Tounouga Remi Lenain Marie A.Amougou Jobert Richie Nansseu | 2019 | Infectious Diseases of Poverty2019，8，2： | 2 |
| 2 | Assessment of Pb retention coefficient and nutrient utilization in growing pigs fed diets with added clinopalolite显示文摘 | Fokas P Zervas G Fegeros K | 2004 | Animal Feed Science and Technology2004，117，： | 1 |
| 3 | Transforming growth factor-beta-regulated expression of genes in macrophages implicated in the control of cholesterol homoeostasis 显示文摘 | Ramji D P Singh N N Foka P | 2006 | Bioehem Soc Trans2006，34，6： | 1 |
| 4 | Assessment of Pb retention coefficientand nutrient utilizationin growing pigsfed dietswith addedclinoptilolite显示文摘 | Fokas P Zervas G Fegeros K | 2004 | Animal Feed Science and Technology2004，117，： | 1 |
| 5 | Sympleetic structures, their Backlund transformations and hereditary symmetries显示文摘 | FUCHSSTEINER B FOKAS A | 1981 | Physica D1981，4，： | 1 |
| 6 | Cyanobacterial cyclopeptides as lead compounds to novel targeted cancer drugs 显示文摘 | Sainis I Fokas D Varell K | 2010 | Mar Drugs2010，8，3： | 1 |
| 7 | The role of radiotherapy in the multimodal management of esophageal cancer 显示文摘 | FOKAS E WEISS C RODEL C | 2013 | Dig Dis2013，31，1： | 1 |
| 8 | Ion beam radio-biology and cancer:time to update ourselves显示文摘 | Fokas E Kraft G An H Engenhart-Cabillic R | | 0，，： | 1 |
| 9 | CCAAT/enhancer-binding proteins: structure, function and regulation显示文摘 | Ramji DP Foka P | 2002 | Biochem J2002，365，3： | 1 |
| 10 | Novel tumour-specific promoters for transcriptional targeting of hep- atocellular carcinoma by herpes simplex virus vectors显示文摘 | FOKA P POURCHET A HERNANDEZ-ALCOCEBA R | 2010 | J C ene Med2010，12，12： | 1 |
| 11 | Symmetries and Integrability显示文摘 | Fokas A S | 1987 | Studies in applied mathematics1987，77，： | 1 |
| 12 | NVP-BEZ235 and NVP-BGT226, dual phosphatidylinositol 3 -kinase/mammalian target ofrapamycin inhibitors, enhance tumor and endothelial cellradiosensitivity显示文摘 | Fokas E Yoshimura M Prevo R | 2012 | Radiat Oncol2012，7，： | 1 |
| 13 | Symplectic structures,their Backlund transformations and hereditary symmetries 显示文摘 | Fuchssteiner B Fokas A S | 1981 | Physica D: Nonlinear Phenom- ena1981，4，1： | 1 |
| 14 | Tumor regression grading after preoperative chemoradiotherapy for locally advanced rectal carcinoma revisited: updated results of the CAO/ARO/AIO-94 trial显示文摘 | Fokas E Liersch T Fietkau R | 2014 | J Clin Oncol2014，32，15： | 1 |
| 15 | NVP-BEZ235 and NVP-BGT226,dual phosphatidylinositol 3-kinase/mam- malian target of rapamyein inhibitors,enhance tumor and endothelial cell radiosensitivity 显示文摘 | Fokas E Yoshimura M Prevo R | 2012 | Radiat Oncol2012，7，： | 1 |
| 16 | Sympletic structures,their backlund transformations and hereditary symmetries显示文摘 | Fuchssteiner B Fokas A | 1981 | Phys D1981，4，1： | 1 |
| 17 | High-quality near-field optical probes by tube etching 显示文摘 | Stockle R Fokas L Deckert V | 1999 | Appl Phys Lett1999，75，： | 1 |
| 18 | Dual inhibition of the PI3K/mTOR pathway increases tumor radiosensitivity by normalizing tumor vas- culature显示文摘 | Fokas E Im JH Hill S | 2012 | Cancer Res2012，72，1： | 1 |
| 19 | Ion beam radiobiology and cancer: time to update ourselves显示文摘 | Fokas E Kraft G An H Engenhart-Cabillic R | 2009 | Biochim Biophys Acta2009，1796，： | 1 |
| 20 | Metastasis: the seed and soil theory gains identity 显示文摘 | Fokas E Engenhart-Cabillic R Daniilidis K | 2007 | Cancer Metastasis Rev2007，26，34： | 1 |
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