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| 1 | Competition between human cells by entosis显示文摘人的癌由被知道为营养素和生长因素间接地竞争的肿瘤房间的复杂混合物组成。肿瘤房间是否能也直接竞争,例如由对手的消除,不被知道。这里,我们证明人的房间能直接由称为 entosis 的吞没的机制竞争。由 entosis,当时,房间被吞没,或吃活,并且随后经历房间死亡。我们发现吞没的身份(“ winner”) 并且吞没(“ loser”) 房间被 RhoA 和肌动球朊控制的机械 deformability 支配,有高 deformability 的肿瘤房间在此优先地吞没并且 outcompete 有在异构的人口的低 deformability 的附近的房间。我们进一步发现那激活的 Kras 并且 Rac 发信号由 downregulating 给予获胜者地位到房间可收缩的肌浆球蛋白,允许最后经历房间死亡的附近的房间的成为主观。最后,我们计算 cell-in-cell 形成的精力风景,表明那一机械在获胜者和输家房间之间微分被要求让 entosis 继续。这些数据在发生在人的肿瘤的哺乳动物的房间定义竞争的机制。 | Qiang Sun Tianzhi Luo Yixin Ren Oliver Florey Senji Shirasawa Takehiko Sasazuki Douglas N Robinson Michael Overholtzer | 2014 | Cell Research2014，24，11： | 8 |
| 2 | Isolation of factorl 显示文摘 | Bazemore A Florey E Elliott K | 1957 | Neurochem1957，，1： | 1 |
| 3 | , Analytical profiles of Drug Substances 显示文摘 | Florey K | 1981 | Academic Press New York1981，4，： | 1 |
| 4 | Time,Teams,and Task Performance:Changing Effects of Surface and Deep Level Diversity on Group Functioning显示文摘 | Harrison D A K H Price J H Gavin A T Florey | 2002 | Academy of Management Journal2002，45，： | 1 |
| 5 | Isolation of factor I显示文摘 | Bazemore AW ElliottK AC Florey E | 1957 | Neurochem1957，，1： | 1 |
| 6 | Isolation of factor I显示文摘 | Bazemore AW Elliott KAC Florey E | 1957 | Journal of Neurochemistry1957，1，4： | 1 |
| 7 | Safe disposal of inflamma-tory monosodium urate monohydrate crystals by differentiated mac-rophages显示文摘 | Landis RC Yagnik DR Florey O | 2002 | Arthritis Rheum2002，46，11： | 1 |
| 8 | Safe disposal of inflammatory monosodium urate monohydrate crystals by differentiated macrophages显示文摘 | Landis RC Yagnik DR Florey O | | 0，，： | 1 |
| 9 | Exposure to environmental tobacco smoke in nonsmoking pregnancy women in relation to birth weight显示文摘 | Rebagliato M Florey CD Bolumar F | 1995 | Am J Epidemiol1995，142，： | 1 |
| 10 | Macrophage release of transforming growth factor beta1 during resolution of monosodium urate monohydrate crystal-induced inflammation显示文摘 | Yagnik DR Evans B J Florey O | | 0，，： | 1 |
| 11 | Relative contribution of PECAM-1 adhesion and signaling to the maintenance of vascular integrity显示文摘 | Privratsky JR Paddock CM Florey O | | 0，，9： | 1 |
| 12 | Autophagy machinery mediates macroendoeytic processing and entotic cell death by targeting single membranes显示文摘 | Florey O Kim SE Sandoval CP | 2011 | Nat cell biol2011，13，11： | 1 |
| 13 | Safe disposal of inflammatory monosodium urale monohydrate crystals by differentiated macrophages显示文摘 | Landis RC Yagnik DR Florey O | 2002 | Arthritis Rheum2002，46，： | 1 |
| 14 | Time, teams, and task performance: Changing effects of surface-and deep-level diversity on group functioning 显示文摘 | Harrison D A Price K H Gavin J H Florey A T | 2002 | Academy of Management Journal2002，45，5： | 1 |
| 15 | Is antennal care apportioned according to obstetric risk? The Scottish antennal care study 显示文摘 | Tucker J Florey CV Howie P | 1994 | Journal of Public Health Medicine1994，16，1： | 1 |
| 16 | Serial in vivo passage of HIV-1infection in Macaca nemestrina 显示文摘 | Ary MB Schmidt A Florey MY | 1997 | Virology1997，238，2： | 1 |
| 17 | nalytical rofiles of Drug显示文摘 | K | 1979 | Stances1979，8，： | 1 |
| 18 | Association between gas cooking and respiratory disease in children 显示文摘 | Melia R Florey CV Altman DG | 1977 | Br Med J1977，2，： | 1 |
| 19 | Relative contribution of PECAM-1 adhesion and signaling to the maintenance of vascular integrity显示文摘 | Privratsky JR Paddock CM Florey O | 2011 | J Cell Sci2011，124，9： | 1 |
| 20 | The endothelial cell显示文摘 | Florey L | 1966 | Br Med J1966，2，1： | 1 |
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