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| 1 | CABYR binds to AKAP3 and Ropporin in the human sperm fibrous sheath显示文摘钙绑定酷氨酸调整 phosphorylation 的蛋白质(CABYR ) 是高度多态的钙绑定 tyrosine-/threonine-phosphorylated 和 serine-/threonine-phosphorylated 涉及 capacitation 的含纤维的鞘(FS ) 蛋白质。一个通常认为的领域(氨基酸 12 鈥 ? 8 ) 对类型 II 营地依赖者蛋白质 kinase A (RII ) dimerisation 和抛锚 kinase 蛋白质(AKAP ) 的规章的子单元相应在 N 终点的蛋白质 kinase A 的有约束力的领域建议那 CABYR 可以自我装配并且绑在 AKAP。而且,有证据, CABYR 与 AKAP 限制了相互作用。然而,推进在 CABYR 之间的证据和新关系,包括 AKAP,另外的 FS 蛋白质将在理解 FS 的基本生理学是有用的。在这研究,为不可溶解的蛋白质的 co-immunoprecipitation 的新策略,以及在有集体 spectrometry 和西方的污点的联合的标准 co-immunoprecipitation 方法,被采用探索在 CABYR, AKAP3 和 Ropporin 之间的关系。结果证明 AKAP3 是有由 anti-CABYR-A polyclonal 抗体的 CABYR 的 co-immunoprecipitated,并且,相反地, CABYR 也是有由 anti-AKAP3 polyclonal 抗体的 AKAP3 的 co-immunoprecipitated。包含蛋白质的另一象 RII 一样域, Ropporin,也是有 CABYR 的 co-immunoprecipitated,显示 Ropporin 是 CABYR 的绑定之一合伙。在 CABYR, AKAP3 和 Ropporin 之间的相互作用被酵母证实二混血儿的试金。进一步的分析显示出那 CABYR 不仅由它的 RII 领域绑在 AKAP3 而且除象 RII 一样领域以外通过另外的区域绑在 Ropporin。这是 CABYR 变体形成的第一示范不仅有 scaffolding 蛋白质 AKAP3 而且与在人的精子 FS 的另一象 RII 一样包含域的蛋白质的建筑群。 | Yan-Feng Li Wei He Arabinda Mandal Young-Hwan Kim Laura Digilio Ken Klotz Charles J Flickinger John C Herr | 2011 | Asian Journal of Andrology2011，13，2： | 5 |
| 2 | Two-dimensionalgel electrophoretie analysis of vectorially labeled surface proteins of human spermatozoa 显示文摘 | Naaby Hansen S Flickinger C J Herr J C | 1997 | Biol Reprod1997，56，3： | 1 |
| 3 | Radiosurgery for hemangiomas of the cavernous sinus and orbit: technical case report 显示文摘 | THOMPSON T P LUNSFORD L D FLICKINGER J C | 2000 | Neurosurgery2000，47，3： | 1 |
| 4 | A comparison of shear bond strengths of orthodontic brackets using various light sources, light guides, and cure times 显示文摘 | Evans LJ Peters C Flickinger C | 2002 | Am J Orthod Dentofacial Orthop2002，121，5： | 1 |
| 5 | Stereotactic radio surgery for trigeminal neuralgia,amulti-institution study using the gamma unit显示文摘 | kondziolka D Lunsford LD Flickinger J C | 1996 | Neurosurgery1996，84，： | 1 |
| 6 | Stereotactic Radiosurgery in Children and Adolescents 显示文摘 | Kondziolka D Lunsford L D Flickinger J C | 1990 | Pediatr Neurosurg1990，16，： | 1 |
| 7 | Ste- reotactic radiosurgery for brain metastasis from renal cell carcinoma显示文摘 | MORI Y KONDZIOLKA D FLICKINGER J C | 1998 | Cancer1998，83，2： | 1 |
| 8 | A comparison of shearbond strengths of orthodontic brackets using various lightsources, light guides,and cure times 显示文摘 | EvansLJ Peters C Flickinger C | 2002 | Am J OrthoDentofacial 0rthop2002，121，5： | 1 |
| 9 | Clinical outcomes after stereotactic radiosurgery for idiopathic trigeminal neuralgia显示文摘 | Maesawa S Salame C Flickinger JC | 2001 | J Neurosurg2001，94，1： | 1 |
| 10 | Fructooligosaccharides and Lactobacillus acidophilus modify bowelfunction and protein catabolites excreted by healthy humans显示文摘 | SWANSON K S GRIESHOP C M FLICKINGER E A | 2002 | J Nutr2002，132，： | 1 |
| 11 | Clinical outcomes after stereotactic radio surgery for idiopathic trigeminal neuralgia显示文摘 | Salame C Flickinger JC | 2001 | J Neurosurg2001，94，： | 1 |
| 12 | A comparison of shear bond strengths f orthodontic brackets using various light sources, light guides and cune times 显示文摘 | Evans LJ Peters C Flickinger C | 2002 | Am J Orthod Dentofac Orthop2002，121，5： | 1 |
| 13 | Stereotacticradio surgery of arteriovvenous malformation of the brain显示文摘 | Lunsford L D kondziolka D Flickinger J C | 2005 | J Nerrosurg2005，75，： | 1 |
| 14 | A multi-institutional analysis of complication outcomes after arteriovenous malformation radiosurgery显示文摘 | FLICKINGER J C KONDZIOLKA D LUNSFORD L D | 1999 | Int J Radiat Oncol Boil Phys1999，44，1： | 1 |
| 15 | Stereotactic radiosurgery for trigeminal neuralgia: a multiinstitutional study using the gamma unit 显示文摘 | KONDZIOLKA D LUNSFORD L D FLICKINGER J C | 1996 | J Neurosurg1996，84，6： | 1 |
| 16 | Trigeminal neuralgia radiosurgery: the University of Pittsburgh experience 显示文摘 | KONDZIOLKA D FLICKINGER J C LUNSFORD L D | 1996 | Stereotact Funct Neurosurg1996，66，1： | 1 |
| 17 | Does increased nerve length within the treatment volume improve trigeminal neuralgia radiosurgery? a prospective double-blind, randomized study显示文摘 | John C Flickinger Bruce E Pollock Douglas Kondziolka Loi K Phuong Robert L Foote Scott L Stafford L.Dade Lunsford | 2001 | International Journal of Radiation Oncology Biology Physics2001，，2： | 1 |
| 18 | Gastrointestinal and immunological responses of senior dogs to chicory and mannan oligosaccharides 显示文摘 | Grieshop C M Flickinger E A Brucek J | 2004 | Archives of Animal Nutrition2004，58，6： | 1 |
| 19 | Current biological research in conversion of cellulosic carbohydrates into liquid fuels: How far have we come? 显示文摘 | Flickinger M C | 1980 | Biotechnology and Bioengineering1980，22，1： | 1 |
| 20 | What Factors Predict the Response of Larger Brain Metastases to Radiosurgery?显示文摘 | Huai-che Yang Hideyuki Kano L Dade Lunsford Ajay Niranjan John C Flickinger Douglas Kondziolka | 2011 | Neurosurgery2011，，3： | 1 |
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