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48篇 您的检索式:作者名="Fiskus W"
    题名 作者 年代 出处 被引量
1Heat shock protein 90 inhibition depletes TrkA levels and signaling in human a- cute leukemia cells 显示文摘Rao R Nalluri S Fiskus W 2010Mol Cancer Ther2010,9,:1
2Cotreat ment with panobinostatand JAK2 inhibitor TGI01209 attenuates JAK2V617F levels andsignaling and exerts synergistic cytotoxic effects against human my-eloproliferative neoplastic cells 显示文摘Wang Y Fiskus W Chong DG 2009Blood2009,114,24:1
3Histone deacetylase inhibitors deplete enhancer of zeste 2 and associated polycomb repressive complex 2 proteins in human acute leukemia cells显示文摘Fiskus W Pranpat M Balasis M 2006Mol Cancer Ther2006,5,12:1
4Pan histone deacety- lase inhibitor panobinostat depletes CXCR4 levels and signaling and exerts synergistic antimyeloid activity in combination with CXCR4 antagonists 显示文摘Mandawat A Fiskus W Buckley K M 2010Blood2010,116,24:1
5Cotreatment with vorinostat (suberoylanilide hydroxamic acid) enhances activity of dasatinib (BMS-354825) against imatinib mesylate-sensitive or imatinib mesylate-resistant chronic myelogenous leukemia cells 显示文摘FISKUS W PRANPAT M BALASIS M 2006Cancer Res2006,12,19:1
6HDAC6 inhibition enhances 17-AAG-mediated abrogation of hsp90 chaperone function in human leukemia cells 显示文摘Rao R Fiskus W Yang Y 2008Blood2008,112,5:1
7Coordinated silencing of MYC-mediated miR-29 by HDAC3 and EZH2 as a therapeutic target of histone modification in aggressive B-Cell lymphomas显示文摘Zhang X Zhao X Fiskus W 2012Cancer Cell2012,22,4:1
8HDAC6 inhibition enhances 17-AAG-mediated abrogation of hsp90 chaperone function in human leukemia cells显示文摘Rao R Fiskus W Yang Y 2008Blood2008,112,5:1
9Combination of the histone deacetylase inhibitor LBH589 and the HSP90 inhibitor 17-AAG is highly active against human CML-BC cells and AML cells with activating mutation of FLT-3显示文摘George P Bali P Annavarapu S Scuto A Fiskus W Guo F 2005Blood2005,105,4:1
10Phase I - II study of vorinostat plus paclitaxel and bevacizumab in metastatic breast cancer: evidence for vorinostat- induced tubulin acety- lation and Hsp90 inhibition in vivo显示文摘RAMASWAMY B FISKUS W COHEN B 2012Breast Cancer Res Treat2012,132,3:1
11Preclinical and phase i results of decitabine in combination with midostaurin (PKC412) for newly diagnosed elderly or relapsed/refractory adult patients with acute myeloid leukemia显示文摘Williams CB Kambharnpati S Fiskus W 2013Pharmacothera- py2013,33,12:1
12Combined epigenetic therapy with the histone methyltransferase EZH2 inhibitor 3-deazaneplanocin A and the historic deacetylase inhibitor panobinostat against human AML cells显示文摘Fiskus W Wang Y Sreekumar A 2009Blood2009,114,:1
13Panobinostat treatment depletes EZH2 and DNMT1 levels and enhances deeitabine mediated de- repression of Jun B and loss of survival of human acute leukemia cells 显示文摘Fiskus W Buckley K Rao R 2009Cancer Biol Ther2009,8,:1
14Phase Ⅰ-Ⅱ study of vorinostat plus paclitaxel and bevacizumab in metastasis breast cancer:evidence for vorinostat-induced tubulin acetylation and Hsp90 inhibition in vivo显示文摘Ramaswamy B Fiskus W Cohen B 2012Breast Cancer Res Treat2012,132,3:1
15Coordinated silencing of MYC-mediated miR-29 by HDAC3 and EZH2 as a therapeutic target of histone modification in aggressive B-Cell lymphomas 显示文摘Zhang X Zhao X Fiskus W 2012Cancer Cell2012,22,4:1
16Hsp90 inhibitor-me- diated disruption of chaperone association of ATR with hsp90 sensitizes cancer cells to DNA damage显示文摘Ha K Fiskus W Rao R 2011Mol Cancer Ther2011,10,7:1
17Co treatment with panobinostat and JAK2 inhibitor TG101209 atterative neoplastic cells 显示文摘Wang Y Fiskus W Chang D G 2009Blood2009,114,:1
18Highly active combination of BRD4 antagonist and histone deacetylase inhibitor against human acute mydoid leukemia cells 显示文摘Fiskus W Sharma S Qi J 2014Mol Cancer Ther2014,13,5:1
19Role of CAAT/enhancer binding protein homologous protein in panobinostat-mediated potentiation of bortezomib-induced lethal endoplasmic reticulum stress in mantle cell lymphoma cells显示文摘Rao R Nalluri S Fiskus W 2010Clin Cancer Res2010,16,:1
20Phase II trial of panobinostat, an oral pan-deacetylase inhibitor in patients with primary myelofibrosis, post-essential thrombocythaemia, and post-polyeythaemia vera myelofi- brosis 显示文摘DeAngelo DJ Mesa RA Fiskus W 2013Br J Haemato12013,162,3:1
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