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| 1 | Liver transplantation in patients with incidental hepatocellular carcinoma/cholangiocarcinoma and intrahepatic cholangiocarcinoma: a single-center experience显示文摘BACKGROUND: Reports of liver transplantation(LT) in patients with mixed hepatocellular carcinoma/cholangiocarcinoma(HCC/CC) and intrahepatic cholangiocarcinoma(ICC) are modest and have been mostly retrospective after pathological categorization in the setting of presumed HCC. Some studies suggest that patients undergoing LT with small and unifocal ICC or mixed HCC/CC can achieve about 40%-60% 5-year post-transplant survival. The study aimed to report our experience in patients undergoing LT with explant pathology revealing HCC/CC and ICC.METHODS: From a prospectively maintained database, we performed cohort analysis. We identified 13 patients who underwent LT with explant pathology revealing HCC/CC or ICC. RESULTS: The observed recurrence rate post-LT was 31%(4/13) and overall survival was 85%, 51%, and 51% at 1, 3 and 5 years, respectively. Disease-free survival was 68%, 51%, and 41% at 1, 3 and 5 years, respectively. In our cohort, four patients would have qualified for exception points based on updated HCC Organ Procurement and Transplantation Network imaging guidelines. CONCLUSIONS: Lesions which lack complete imaging characteristics of HCC may warrant pre-LT biopsy to fully elucidate their pathology. Identified patients with early HCC/CC or ICC may benefit from LT if unresectable. Additionally, incorporating adjunctive perioperative therapies such as in the case of patients undergoing LT with hilar cholangiocarcinoma may improve outcomes but this warrants further investigation. | Mohammed Elshamy Naftali Presser Abdulrahman Y Hammad Daniel J Firl Christopher Coppa John Fung Federico N Aucejo | 2017 | Hepatobiliary & Pancreatic Diseases International2017，16，3： | 6 |
| 2 | Fast CT/PET registration based on partial volume matching显示文摘 | E.A Firle S Wesarg C Dold | 2004 | International Congress Series2004，，： | 1 |
| 3 | Cellular Telephone Interference With Medical Equipment显示文摘 | Tri JL Severson RP Firl AR | 2005 | Mayo Clin Proc2005，80，10： | 1 |
| 4 | Fast CT/PET registration based on partial volume matching显示文摘 | Firle EA Wesarg S Dold C | 2004 | International Congress Series2004，1268，： | 1 |
| 5 | F etal brain transplantsireduction of congnitive deficits in rats with frontal cortex lesions显示文摘 | Labber R Firl A Mufson EJ | 1983 | Science1983，221，： | 1 |
| 6 | Measurement of bowing of the radius显示文摘 | Firl M Wunsch L | 2004 | J Bone Joint Surg Br2004，86，7： | 1 |
| 7 | Determination of the fatty acid profile of neutral lipids,free fatty acids and phospholipids in human plasma显示文摘 | Firl N Kienberger H Hauser T | 2013 | Clinical Chemistry and Laboratory Medicine2013，51，4： | 1 |
| 8 | Extrasynaptic glutamate and inhibitory neurotransmission modulate ganglion cell par- ticipation during glutamatergic retinal waves显示文摘 | Firl A Sack G S Newman Z L | 2013 | Neurophysi- ol2013，109，7： | 1 |
| 9 | Fast CT/PET registration based on partial volume matching显示文摘 | Firle EA Wesarg S Dold C | | 0，，： | 1 |
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