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| 1 | Helicobacter pylori:Future perspectives in therapy reflecting three decades of experience显示文摘The rising prevalence of antibiotic resistance has created a need to reassess the established Helicobacter pylori(H.pylori)eradication protocols,and to develop new ones.Various bacterial and host factors are evaluated,and their contribution to eradication failure is estimated.For a long time being considered the cornerstone eradication scheme,the standard triple therapy has been replaced with novel,more efficient regimens,namely sequential and concomitant,along with the emergence of a new design of bismuth quadruple therapy.A rescue levofloxacin based regimen has overcome the fear of therapy failure due to higher prevalence of dual resistant(clarithromycin and metronidazole)H.pylori.Culture-free and efficient susceptibility test are reestablishing the concept of tailored therapy,making eradication success close to originally desirable rates.Alleviating therapy side effects and improving patient compliance are as important as choosing appropriate eradication schemes,so various probiotic compound supplements are taken into consideration.Finally,we summarize the emerging efforts and obstacles in creating efficientH.pylori vaccine. | Tajana Filipec Kanizaj Nino Kunac | 2014 | World Journal of Gastroenterology2014，20，3： | 10 |
| 2 | Hepatitis C:New challenges in liver transplantation显示文摘In an era of great achievements in liver transplantation, hepatitis C viral infection(HCV) remains an unsolved problem. As a leading indication for liver transplantation in Western countries, HCV poses a significant burden both before and after transplantation. Post-transplant disease recurrence occurs in nearly all patients with detectable pretransplant viremia, compromising the lifesaving significance of transplantation. Many factors involving the donor, recipient and virus have beenevaluated throughout the literature, although few have been fully elucidated and implemented in actual clinical practice. Antiviral therapy has been recognized as a cornerstone of HCV infection control; however, experience and success are diminished following transplantation in a challenging cohort of patients with liver cirrhosis. Current therapeutic protocols surpass those used previously, both in sustained viral response and side-effect profile. In this article we review the most relevant and contemporary scientific evidence regarding hepatitis C infection and liver transplantation, with special attention dedicated to novel, more efficient and safer antiviral regimens. | Tajana Filipec Kanizaj Nino Kunac | 2015 | World Journal of Gastroenterology2015，21，19： | 2 |
| 3 | Evaluation of corneal graft rejection in a mouse model显示文摘 | Plková J Kuffová L Holá V Filipec M Forrester JV | 2002 | Br J Ophthalmol2002，86，1： | 1 |
| 4 | FTY720 in corneal concordant xenotransplantation 显示文摘 | Sedlakova K Muckersie E Robertson M Filipec M Forrester JV | 2005 | Transplantation2005，79，3： | 1 |
| 5 | Effect of suturing technique on corneal xenograft survival显示文摘 | Sedlakova K Filipec M | 2007 | Cornea2007，26，9： | 1 |
| 6 | Inflammatory bowel disease in liver transplanted patients显示文摘Most common hepatobiliary manifestation of inflammatory bowel disease(IBD) are primary sclerosing cholangitis(PSC) and autoimmune hepatitis, ranking them as the main cause of liver transplantation(LT) in IBD setting. Course of pre-existing IBD after LT differs depending on many transplant related factors. Potential risk factors related to IBD deterioration after LT are tacrolimus-based immunosuppressive regimens, active IBD and cessation of 5-aminosalicylates at the time of LT. About 30% patients experience improvement of IBD after LT, while approximately the same percentage of patients worsens. Occurrence of de novo IBD may develop in 14%-30% of patients with PSC. Recommended IBD therapy after LT is equivalent to recommendations to overall IBD patients. Antitumor necrosis factor alpha appears to be efficient for refractory IBD. Due to potential side effects it needs to be applied with caution. In average 9% of patients require proctocolectomy due to medically refractory IBD or colorectal carcinoma. The most frequent complication in patients who undergo proctocolectomy with ileal-pouch anal anastomosis is pouchitis. It is still undeterminable if LT adds to risk of developing pouchitis in PSC patients. Annual colonoscopies are recommended as surveillance and precaution of colonic malignancies. | Tajana Filipec Kanizaj Maja Mijic | 2017 | World Journal of Gastroenterology2017，23，18： | 1 |
| 7 | Quantitative evaluation of the corneal endothelium in the mouse after grafting显示文摘 | Plskova J Kuffova L Filipec M | 2004 | Br J Ophthalmol2004，88，： | 1 |
| 8 | Genetic algorithm approach for multiple depot capacitated vehicle routing problem solving with heuristic improvements built-in 显示文摘 | Filipec M Skrlec D Krajcar S | 2000 | International Journal of Modeling and Simulation2000，20，4： | 1 |
| 9 | Genetic algorithm approach for multiple depot capacitated vehicle routing problem solving with heuristic improvements built-in显示文摘 | Skrlec D Krajcar S | 2000 | International Journal of Modeling and Simulation2000，20，4： | 1 |
| 10 | Genetic algorithm approach for multiple depot capacitated vehicle routing problem solving with heuristic improvements built-in显示文摘 | Filipec M Skrlec D Krajcar S | 2000 | International Journal of Modeling and Simulation2000，20，4： | 1 |
| 11 | Genetic algorithm approach for multiple depot capacitated vehicle routing problem solving with heuristic improvements显示文摘 | FILIPEC M KRLEC D KRAJCAR S | 2000 | International Journal of Modelling and Simulation2000，20，4： | 1 |
| 12 | Genetic algorithm approach for multiple depot capacitated vehicle routing problem solving with heuristic improvements显示文摘 | Filipec M Skrlec D | 2000 | International Journal of Modeling and Simulation2000，20，4： | 1 |
| 13 | Helicobacter pylori and nonmalignant diseases显示文摘 | Shmuely H Katicic M Filipec Kanizaj T | 2012 | Helicobacter2012，，： | 1 |
| 14 | Prevention of corneal allograft rejection in a mouse model of high risk recipients显示文摘 | Vitova A Filipec M Zajicova A | | 0，，： | 1 |
| 15 | A rapid separation of tw o distinct populations of mouse corneal epithelial cells w ith limbal stem cell characteristics by centrifugation on percoll gradient显示文摘 | Krulova M Pokorna K Lencova A Fric J Zajicova A Filipec M | 2008 | Invest Ophthalmol Vis Sci2008，49，9： | 1 |
| 16 | Noninvasive markers of liver steatosis and fibrosis after liver transplantation-Where do we stand?显示文摘In the last two decades,advances in immunosuppressive regimens have led to fewer complications of acute rejection crisis and consequently improved shortterm graft and patient survival.In parallel with this great success,long-term posttransplantation complications have become a focus of interest of doctors engaged in transplant medicine.Metabolic syndrome(MetS)and its individual components,namely,obesity,dyslipidemia,diabetes,and hypertension,often develop in the post-transplant setting and are associated with immunosuppressive therapy.Nonalcoholic fatty liver disease(NAFLD)is closely related to MetS and its individual components and is the liver manifestation of MetS.Therefore,it is not surprising that MetS and its individual components are associated with recurrent or“de novo”NAFLD after liver transplantation(LT).Fibrosis of the graft is one of the main determinants of overall morbidity and mortality in the post-LT period.In the assessment of post-LT steatosis and fibrosis,we have biochemical markers,imaging methods and liver biopsy.Because of the significant economic burden of post-LT steatosis and fibrosis and its potential consequences,there is an unmet need for noninvasive methods that are efficient and cost-effective.Biochemical scores can overestimate fibrosis and are not a good method for fibrosis evaluation in liver transplant recipients due to frequent post-LT thrombocytopenia.Transient elastography with controlled attenuation parameter is a promising noninvasive method for steatosis and fibrosis.In this review,we will specifically focus on the evaluation of steatosis and fibrosis in the post-LT setting in the context of de novo or recurrent NAFLD. | Ivana Mikolasevic Sanja Stojsavljevic Filip Blazic Maja Mijic Delfa Radic-Kristo Toni Juric Nadija Skenderevic Mia Klapan Andjela Lukic Tajana Filipec Kanizaj | 2021 | World Journal of Transplantation2021，11，3： | 1 |
| 17 | Prevention of corneal allograft rejection in a mouse model of high risk recipients显示文摘 | Vítová A Filipec M Zajícová A | 2004 | Br J Ophthalmol2004，88，10： | 1 |
| 18 | Serum Antibodies Positivity to 12 Helicobacter pylori Virulence Antigens in Patients with Benign or Malignant Gastroduodenal Diseases – Cross-sectional Study显示文摘 | Tajana Filipec Kani?aj Miroslava Kati?i? Vladimir Prese?ki Slavko Ga?parov Vesna Coli? Cvrlje Branko Kolari? Anna Mrzljak | 2009 | Croatian Medical Journal2009，，2： | 1 |
| 19 | Lymph node removal enhances corneal graft survival in mice at high risk of rejection显示文摘 | Plskova J Holan V Filipec M | 2004 | BMC Ophthalmol2004，4，： | 1 |
| 20 | Thygeson' s keratitis-clinical characteristics and therapy显示文摘 | Oudova P Filipec M | 2004 | Cesk Slov Oftalmol2004，60，1： | 1 |
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