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| 1 | 北京和巴黎社区获得性肺炎急诊治疗的比较显示文摘目的比较北京和巴黎社区获得性肺炎的急诊治疗情况。方法收集2003年10月1日至2004年9月30日北京大学人民医院急诊科和巴黎市中心H(?)tel-Dieu 医院急诊科的社区获得性肺炎患者病情和治疗方面的信息,通过Fine危险分层评估两组患者,并对治疗进行比较。结果(1)两组患者在五个 Fine分级中的分布差异没有统计学意义(P>0.05),因此两组患者病情有可比性。(2)北京组患者和巴黎组相比,三代头孢类、碳青霉烯类等高级抗生素的用药比例高(P<0.01),而青霉素和大环内酯类用药等基础药物的比例低(P<0.01);静脉用药比例高,而口服药比例低(P<0.01)。北京组病人抗生素治疗和指南的一致性(59.6%)显著低于巴黎组患者(88.6%,P<0.01)。(3)北京组患者全部在4 h 内得到抗生素治疗,而巴黎组患者92例(52.2%)在4 h 内得到抗生素治疗。(4)急诊观察室停留时间北京组患者显著长于巴黎组患者。结论北京和巴黎社区获得性肺炎的急诊处理有很大的不同,我们应借鉴巴黎,以完善自己。 | 薛晓艳 朱继红 Emanuel FIERE Jean-Louis POURRIAT | 2006 | 中华急诊医学杂志2006，15，12： | 5 |
| 2 | Pancreatic elastase induces liver injury by activating cytokine production within Kupffer cells via nuclear factor-kappa B显示文摘 | Michel M. Murr M.D. Jun Yang M.D. Adam Fier B.A. Pam Kaylor M.S. Stephen Mastorides M.D. James G. Norman M.D | 2002 | Journal of Gastrointestinal Surgery2002，，3： | 2 |
| 3 | Regulation of Kupffer cell TNF gene expression during experimental acute pancreatitis: The role of p38-MAPK, ERK1/2, SAPK/JNK, and NF-κB显示文摘 | Michel M. Murr M.D. Jun Yang M.D. Adam Fier B.A. Scott F. Gallagher M.D. Gay Carter B.A. William R. Gower Ph.D. James G. Norman M.D | 2003 | Journal of Gastrointestinal Surgery2003，，1： | 2 |
| 4 | Computer notes Precise:Software for prediction of cis-acting regulatory elements显示文摘 | BERLOO R V FIERS M | 2005 | J Heredity2005，，： | 1 |
| 5 | Liver injury durying acute Pancreatitis:the role of pancreatitis associated as citiefluid(PAAF),p-38 M APK,and caspase 3 in inducing ghepatocy teapoptosis显示文摘 | Adam Fier Yvette Carte | 2003 | The Society for Surgery of the Alimentary Tract2003，7，2： | 1 |
| 6 | Cloning and expression of the canine interferon-gamma gene显示文摘 | Devos K Duerinck F Van Audenhove K Fiers W | 1992 | J Interferon Res1992，12，2： | 1 |
| 7 | Improveddesign and intranasal delivery of an M2e-based humaninfluenza A vaccine 显示文摘 | De Filette M Fiers W Martens W | 2006 | Vaccine2006，24，4446： | 1 |
| 8 | Zonation and structuring factors of meiofauna communities in a tropical seagrass bed(Gazi Bay,Kenya)显示文摘 | DE TROCH M GURDEBEKE S FIERS F | 2001 | Journal of Sea Research2001，45，1： | 1 |
| 9 | Disruption of overlapping transcripts in the ROSA beta geo 26 gene trap strain leads to widespread expression of beta-galactosidase in mouse embryos and hematopoietic cells 显示文摘 | Zambrowicz BP Imamoto A Fiering S | 1997 | Proc Natl Acad Sci USA1997，94，8： | 1 |
| 10 | Recombinant neuraminidase vaccine protects against lethal influenza 显示文摘 | Deroo T Jou WM Fiers W | 1996 | Vaccine1996，14，6： | 1 |
| 11 | Comparison of chemotherapy and autologous and allogeneic transplantation as postinduction regimen in adult acute lymphoblastlc leukemia: A preliminary multicentric study显示文摘 | Fiere D Broustet A Leblond V | 1990 | Hematol Blood Transf1990，33，： | 1 |
| 12 | UniversalM 2 ectodomain-based influenza A vaccines; preclinicaland clinical developments 显示文摘 | Schotsaert M De Filette M Fiers W | 2009 | Expert Rev Vaccines2009，8，4： | 1 |
| 13 | Structure-activity studies of human tumor necrosis factor显示文摘 | Ostade X Tavernier J Fiers W | 1994 | Protein Engineering1994，7，： | 1 |
| 14 | A haplotyp of human angiot- cnsinogcn gone containing -217A increases blood pressure in transgc- nic mice compared with-217G 显示文摘 | Jain S Vinukonda G Fiering SN ct al | 2003 | Am J Physiol Regulatory Intcgrati- vs Comp Physiol2003，295，6： | 1 |
| 15 | Targeted disruption of the type I selenodeiodinase gene(Diol)results in marked changes in thyroid hormone economy in mice显示文摘 | Schneider MJ Fiering SN Thai B | 2006 | Endocrinology2006，147，1： | 1 |
| 16 | Recombinant neuraminidase vaccine protects against lethal in fluenza显示文摘 | Min Jou W and Fiers W | 1996 | Vaccine1996，14，6： | 1 |
| 17 | Improved design and intranasal delivery of an M2e-based human influenza A vaccine 显示文摘 | De Filette M Fiers W Martens W | 2006 | Vaccine2006，24，4446： | 1 |
| 18 | M2 ectodomain-based influenza A vaccines: and clinical developments 显示文摘 | Schotsaert M De Filette M Fiers W | 2009 | Expert Rev2009，8，4： | 1 |
| 19 | Improved design and intranasal delivery of an M2e-based human influenza A vaccine显示文摘 | De Filette M Fiers W Martens W | 2006 | Vaccine2006，24，46： | 1 |
| 20 | Type 3 deiodinase is critical for the maturation and function of the thyroid axis 显示文摘 | Hemandez A Martinez M E Fiering S | 2006 | Journal of Clinical Investigation2006，116，2： | 1 |
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