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| 1 | Clinical classification of symptomatic heterotopic pancreas of the stomach and duodenum:A case series and systematic literature review显示文摘BACKGROUND Heterotopic pancreas(HP)is an aberrant anatomic malformation that occurs most commonly in the upper gastrointestinal tract.While the majority of heterotopic pancreatic lesions are asymptomatic,many manifest severe clinical symptoms which require surgical or endoscopic intervention.Understanding of the clinical manifestations and symptoms of HP is limited due to the lack of large volume studies in the literature.The purpose of this study is to review symptomatic cases at a single center and compare these to a systematic review of the literature in order to characterize common clinical manifestations and treatment of this disease.AIM To classify the common clinical manifestations of heterotopic pancreas.METHODS A retrospective review was conducted of pathologic samples containing heterotopic pancreas from 2000-2018.Review was limited to HP of the upper gastrointestinal tract due to the frequency of presentation in this location.Symptomatic patients were identified from review of the medical records and clinical symptoms were tabulated.These were compared to a systematic review of the literature utilizing Pub Med and Embase searches for papers pertaining to heterotopic pancreas.Publications describing symptomatic presentation of HP were selected for review.Information including demographics,symptoms,presentation and treatment were compiled and analyzed.RESULTS Twenty-nine patient were identified with HP at a single center,with six of these identified has having clinical symptoms.Clinical manifestations included,gastrointestinal bleeding,gastric ulceration with/without perforation,pancreatitis,and gastric outlet obstruction.Systemic review of the literature yielded 232 publications detailing symptomatic cases with only 20 studies describing ten or more patients.Single and multi-patient studies were combined to form a cohort of 934 symptomatic patients.The majority of patients presented with abdominal pain(67%)combined with one of the following clinical categories:(1)Dyspepsia,(n=445,48%);(2)Pancreatitis(n=260,28%);(3)Gastrointestinal bleeding(n=80,9%);and(4)Gastric outlet obstruction(n=80,9%).The majority of cases(n=832,90%)underwent surgical or endoscopic resection with 85%reporting resolution or improvement in their symptoms.CONCLUSION Heterotopic pancreas can cause significant clinical symptoms in the upper gastrointestinal tract.Better understanding and classification of this disease may result in more accurate identification and treatment of this malformation. | Michael T Le Compte Brandon Mason Keenan J Robbins Motoyo Yano Deyali Chatterjee Ryan C Fields Steven M Strasberg William G Hawkins | 2022 | World Journal of Gastroenterology2022，28，14： | 3 |
| 2 | 广谱抗生素在成人肺结核诊断中的应用显示文摘抗生素试验广泛用于菌阴肺结核的诊断已有30多年,尤其是在低资源国家。估计每年至少有2650万疗程的抗生素处方是出于这种做法,这可能增加抗生素的暴露及耐药的发生。为评估抗生素试验的诊断效能,研究人员对相关文献进行了系统综述和荟萃分析。通过检索Medline、Embase和Global Health数据库截至2019年3月15日关于成人疑似结核患者抗生素试验诊断效能的文献,使用QUADAS-2工具评估偏倚风险,使用双变量随机效应模型估算抗生素试验的合并敏感性和特异性,使用I2统计量进行异质性分析。 | Divala TH Fielding KL Kandulu C 刘盛盛(编译) | 2020 | 中华医学杂志2020，100，26： | 2 |
| 3 | Imaging Fourier Transform Spectrometer显示文摘 | Bennett C L Carter M Fields D | 1993 | SPIE1993，1937，： | 1 |
| 4 | Does Insider Trading Impair Market Liquidity?Evidence from IPO Lockup Expirations显示文摘 | Cao C Field L C Hanka G R | 2002 | Journal of Financial and Quantitative Analysis2002，，5： | 1 |
| 5 | Evaluation of electrostatically endothelial cell seeded expanded polytetrafluoroethylene grafts in a canine fem oral artery model显示文摘 | Fields C Cassano A Makhoul RG | 2002 | J Biomater Appl2002，17，2： | 1 |
| 6 | Interleukin -6 in the synovial membrane in rheumatoid arthritis 显示文摘 | FIELD M CHU C Q FELDMANN M | 1991 | Rheumatol Int1991，11，： | 1 |
| 7 | Infection of the Norway lobster Nephrops norvegicus by a Hematodinium-like species of dinoflagellate on the west coast of Scotland 显示文摘 | Field R H Chapman C J Taylor AC | 1992 | Dis Aquat Org1992，13，： | 1 |
| 8 | Synthetic estrogen derivatives demonstrate the functionality of intracellular GPR30 显示文摘 | Revankar C M Mitchell H D Field A S | 2007 | ACS Chem Biol2007，2，8： | 1 |
| 9 | Quantitative determi-nation of 1,4-dioxane and tetrahydrofuran in groundwater bysolid phase extraction GC/MS/MS显示文摘 | ISAACSON C MOHR T K FIELD J A | 2006 | Environmental Scienceand Technology2006，40，23： | 1 |
| 10 | The bainite controversy 显示文摘 | Fielding L C D | 2013 | Materials Science and Technology2013，29，4： | 1 |
| 11 | Individual differences in servant leadership: The roles of values and personality 显示文摘 | Washington R R Sutton C D Field H S | 2006 | Leadership &Organization Development Journal2006，27，8： | 1 |
| 12 | An ap- proach to automatic three-dimensional finite element mesh generation显示文摘 | CAVENDISH J C FIELD D A FREY W H | 1985 | International Journal for Numerical Methods in Engineering1985，21，2： | 1 |
| 13 | Evaluation of clinical management of gonorrhoea using enhanced surveillance in South East Queensland 显示文摘 | Field E Heel K Palmer C | 2010 | Sex Health2010，7，4： | 1 |
| 14 | Surgical resection of the primary tumor is associated with increased long-term survival in pa- tients with Stage IV breast cancer after controlling for site of metas- tasis显示文摘 | Fields R C Jeffe D B Trinkaus K | 2007 | Ann SurgOncol2007，14，12： | 1 |
| 15 | What is 'emerging'? 显示文摘 | Field J A Johnson C A Rose J B | 2006 | Environmental Science & Technology2006，40，23： | 1 |
| 16 | Estimation of the carbon dioxide (CO2 ) ferti- lization effect using growth rate anomalies of CO2 and crop yields since 1961 显示文摘 | Lobell D B Field C B | 2008 | Global Change Biology2008，14，1： | 1 |
| 17 | A narrow-waveband spectral index that tracks diurnal changes in photosynthetic efficient显示文摘 | Gamon J A Penuelas J Field C B | 1992 | Remote Sensing of Environment1992，41，1： | 1 |
| 18 | Melt strength ofpolypropylene : its relevance to thermoforming 显示文摘 | LAU H C BHATACHARYA S N FIELD G J | 1998 | PolymerEngineering Science1998，38，11： | 1 |
| 19 | Bolus oral glutamine protects rats against CPT-1 I-induced diarrhea and differentially activates cytopro- tective mechanisms in host intestine but not tumor显示文摘 | Xue H Sawyer MB Field C J | 2008 | Nut~2008，38，4： | 1 |
| 20 | The design, fabrication and characterization of a silicon microheater for an integrated MEMS gas preconcentrator显示文摘 | YEOM J FIELD C R BAE B | 2008 | J Micromech Microeng2008，18，12： | 1 |
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