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3篇 您的检索式：作者名="Fengling Wan"

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		题名	作者	年代	出处	被引量
	1	Combined peripheral natural killer cell and circulating tumor cell enumeration enhance prognostic efficiency in patients with metastatic triple-negative breast cancer显示文摘Objective:Triple-negative breast cancer(TNBC)is a heterogeneous disease with poor prognosis.Circulating tumor cells(CTCs)are a promising predictor for breast cancer prognoses but their reliability regarding progression-free survival(PFS)is controversial.We aim to verify their predictive value in TNBC.Methods:In present prospective cohort study,we used the Pep@MNPs method to enumerate CTCs in baseline blood samples from 75 patients with TNBC(taken at inclusion in this study)and analyzed correlations between CTC numbers and outcomes and other clinical parameters.Results:Median PFS was 6.0(range:1.0–25.0)months for the entire cohort,in whom we found no correlations between baseline CTC status and initial tumor stage(P=0.167),tumor grade(P=0.783)or histological type(P=0.084).However,among those getting first-line treatment,baseline CTC status was positively correlated with ratio of peripheral natural killer(NK)cells(P=0.032),presence of lung metastasis(P=0.034)and number of visceral metastatic site(P=0.037).Baseline CTC status was predictive for PFS in first-line TNBC(P=0.033),but not for the cohort as a whole(P=0.118).This prognostic limitation of CTC could be ameliorated by combining CTC and NK cell enumeration(P=0.049).Conclusions:Baseline CTC status was predictive of lung metastasis,peripheral NK cell ratio and PFS in TNBC patients undergoing first-line treatment.We have developed a combined CTC-NK enumeration strategy that allows us to predict PFS in TNBC without any preconditions.	Xiaoran Liu Ran Ran Bin Shao Hope S.Rugo Yanlian Yang Zhiyuan Hu Zewen Wei Fengling Wan Weiyao Kong Guohong Song Hanfang Jiang Xu Liang Ruyan Zhang Ying Yan Guobing Xu Huiping Li	2018	Chinese Journal of Cancer Research2018，30，3：	4
	2	Enhanced adsorption of humie acids on ordered mesoporous carbon eompared with mieroporous activated carbon 显示文摘	LIU Fengling XU Zhaoyi WAN Haiqing	2011	Environmental Toxieology and Chemistry2011，30，4：	1
	3	Elevated level of peripheral CD8 + CD28 ? T lymphocytes are an independent predictor of progression-free survival in patients with metastatic breast cancer during the course of chemotherapy显示文摘	Guohong Song Xiaoli Wang Jun Jia Yanhua Yuan Fengling Wan Xinna Zhou Huabing Yang Jun Ren Jiezhun Gu Herbert Kim Lyerly	2013	Cancer Immunology Immunotherapy2013，，6：	1

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