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| 1 | The RppC-AvrRppC NLR-effector interaction mediates the resistance to southern corn rust in maize显示文摘Southern corn rust(SCR),caused by the fungal pathogen Puccinia polysora,is a major threat to maize pro-duction worldwide.Efficient breeding and deployment of resistant hybrids are key to achieving durable control of SCR.Here,we report the molecular cloning and characterization of RppC,which encodes an NLR-type immune receptor and is responsible for a major SCR resistance quantitative trait locus.Further-more,we identified the corresponding avirulence effector,AvrRppC,which is secreted by P.polysora and triggers RppC-mediated resistance.Allelic variation of AvrRppC directly determines the effectiveness of RppC-mediated resistance,indicating that monitoring of AvrRppC variants in the field can guide the rational deployment of RppC-containing hybrids in maize production.Currently,RppC is the most frequently deployed SCR resistance gene in China,and a better understanding of its mode of action is crit-ical for extending its durability. | Ce Deng April Leonard James Cahill Meng Lv Yurong Li Shawn Thatcher Xueying Li Xiaodi Zhao Wenjie Du Zheng Li Huimin Li Victor Llaca Kevin Fengler Lisa Marshall Charlotte Harris Girma Tabor Zhimin Li Zhiqiang Tian Qinghua Yang Yanhui Chen Jihua Tang Xintao Wang Junjie Hao Jianbing Yan Zhibing Lai Xiaohong Fei Weibin Song Jinsheng Lai Xuecai Zhang Guoping Shu Yibo Wang Yuxiao Chang Weiling Zhu Wei Xiong Juan Sun Bailin Li Junqiang Ding | 2022 | Molecular Plant2022，15，5： | 6 |
| 2 | Renal sympathetic denervation in therapy resistant hypertension-pathophysiological aspects and predictors for treatment success显示文摘Many forms of human hypertension are associated with an increased systemic sympathetic activity. Especially the renal sympathetic nervous system has been found to play a prominent role in this context. Therefore, catheterinterventional renal sympathetic denervation(RDN) has been established as a treatment for patients suffering from therapy resistant hypertension in the past decade. The initial enthusiasm for this treatment was markedly dampened by the results of the Symplicity-HTN-3 trial, although the transferability of the results into clinical practice to date appears to be questionable. In contrast to the extensive use of RDN in treating hypertensive patients within or without clinical trial settings over the past years, its effects on the complex pathophysiological mechanisms underlying therapy resistant hypertension are only partly understood and are part of ongoing research. Effects of RDN have been described on many levels in human trials: From altered systemic sympathetic activity across cardiac and metabolic alterations down to changes in renal function. Most of these changes could sustainably change long-term morbidity and mortality of the treated patients, even if blood pressure remains unchanged. Furthermore, a number of promising predictors for a successful treatment with RDN have been identified recently and further trials are ongoing. This will certainly help to improve the preselection of potential candidates for RDN and thereby optimize treatment outcomes. This review summarizes important pathophysiologic effects of renal denervation and illustrates the currently known predictors for therapy success. | Karl Fengler Karl Philipp Rommel Thomas Okon Gerhard Schuler Philipp Lurz | 2016 | World Journal of Cardiology2016，8，8： | 5 |
| 3 | 采用不同导管和技术的去肾交感神经术治疗单纯收缩期高血压:一项随机试验结果显示文摘目前认为单纯收缩期高血压(isolated systolic hypertension,ISH)患者经去肾交感神经术(renal sympathetic denervation,RDN)后血压降低。此结论绝大多数来自单极射频导管消融的研究。但采用新的RDN的数据有限。研究者采用比较3种不同RDN方法的RADIOSOUND-HTN(采用不同RDN导管与技术治疗顽固性高血压患者的三臂随机试验)数据,探讨ISH与RDN反应的可能交互作用。 | Fengler K Rommel KP Lapusca R Blazek S Besler C Hartung P von Roeder M Kresoja KP Desch S Thiele H Lurz P 赵狄 练桂丽 | 2019 | 中华高血压杂志2019，27，7： | 2 |
| 4 | Should etomidate be used for rapid-sequence intubation induction in critically ill septic patients?显示文摘 | FENGLER B T | 2008 | Am J Emerg Med2008，26，2： | 1 |
| 5 | Are processed surgical instruments protein free? 显示文摘 | Fengler TW Pahike H Bissen S | 2001 | Zentr Steril2001，9，1： | 1 |
| 6 | Randomized comparison of 36-hour intermediate-dose versus 4-hour high- dose methotrexate infusions for remission induction in relapsed childhood acute lymphoblastic leukemia显示文摘 | Wolfrom C Hartmann R Fengler R | 1993 | J Clin Oncol1993，11，5： | 1 |
| 7 | Should etomidate be used for rapid sequence intubation induction in critically ill septic patients? 显示文摘 | Fengler BT | 2008 | Am J Emerg Med2008，26，2： | 1 |
| 8 | Romantic Love in Courtship: Divergent Paths of Male and Female Students显示文摘 | Fengler A P | 1974 | Journal of Comparative Family Studies1974，5，： | 1 |
| 9 | Evaluation of the mineral content of peripheral bones (radius) by photon-absorption technique in normals as well as in patients with various types of bone diseases(author′s transl)显示文摘 | Fengler F Franke J | 1980 | Radiologe1980，20，10： | 1 |
| 10 | The Arabidopsis dnd1 'defense,no death' gene encodes a mutated cyclic nucleotide-gated ion channel显示文摘 | Clough S J Fengler K A Yu I C | 2000 | Proc Natl Acad Sci USA2000，97，16： | 1 |
| 11 | Maggot therapy in the treatment of wounds of exposed knee prostheses显示文摘 | Wollina U Kinscher M Fengler H | 2005 | Int J Dermatol2005，44，10： | 1 |
| 12 | Randomized comparison of 36 hour intermediate - dose versus 4 hour -hish - dose methotrexate infusions for remission in- duction in relapsed childhood acute lymphoblastic leu- kemia 显示文摘 | Wolform C Hartmann R Fengler R | 1993 | J Olin Oncol1993，11，5： | 1 |
| 13 | Should etomidate be used for rapid sequence intuba- tion induction in critically ill septic patients 显示文摘 | Fengler BT | 2008 | Am J Emerg Med2008，26，2： | 1 |
| 14 | Wavelet Modeling of Regional and Temporal Varia- tions of the Earth's Gravitational Potential Ob- served by GRACE显示文摘 | Fengler M J Freeden W Kohlhaas A | 2007 | Journal of Geodesy2007，81，1： | 1 |
| 15 | Regional Gravity Modeling in Terms of Spherical Base Functions显示文摘 | Schmidt M Fengler M | 2007 | Journal of Geodesy2007，81，： | 1 |
| 16 | Allelic genome structural variations in maize detected by array comparative genome hybridization显示文摘 | André Beló Mary K. Beatty David Hondred Kevin A. Fengler Bailin Li Antoni Rafalski | 2010 | Theoretical and Applied Genetics2010，，2： | 1 |
| 17 | Antineovascular agents in the treatment of eye diseases 显示文摘 | Eichler W Yafai Y Wiedemann P Fengler D | 2006 | Curt Pharm Des2006，12，21： | 1 |
| 18 | Randomized comparison of 36-hour intermediate-dose versus 4-hour- high-dose methotrexate infusions for remission induction in relapsed childhood acute lymphoblastic leukemia 显示文摘 | Wolform C Hartmann R Fengler R | 1993 | J Clin Oneol1993，11，5： | 1 |
| 19 | Randomized comparison of 36- hourintermediate - dose versus 4 - hour high - dose methotrexate infusions for remission induction in relapsed childhood acute lymphoblastic leukemia显示文摘 | Wolfrom C Hartmann R Fengler R | 1993 | J Clin Oncol1993，11，15： | 1 |
| 20 | Maggot therapy in the treatment of wounds of exposed knee prostheses显示文摘 | Wollina U Kinscher M Fengler H | 2005 | Int JDermatol2005，44，： | 1 |
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